| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $3,438,681,237 | E22 | published | launch: space | Charlestown, MA | 2024 |
| GORDON E AND BETTY I MOORE FOUNDATION | $2,663,649,577 | T20 | published | launch: space | Palo Alto, CA | 2024 |
| AEROSPACE CORPORATION | $1,623,067,000 | U30 | published | launch: space | Chantilly, VA | 2024 |
| EISENHOWER MEDICAL CENTER | $1,470,145,483 | E22 | published | launch: space | Rancho Mirage, CA | 2024 |
| PRESBYTERIAN MEDICAL CENTER OF THE UNIVERSITY OF PENNSYLVANIA HEALTH | $1,418,193,001 | E22 | published | launch: space | Philadelphia, PA | 2024 |
| CHARLES STARK DRAPER LABORATORY INC | $949,348,102 | U40 | published | launch: space | Cambridge, MA | 2024 |
| BRIDGEPORT HOSPITAL | $925,337,466 | E22 | published | launch: space | Bridgeport, CT | 2024 |
| PIKEVILLE MEDICAL CENTER INC | $789,640,637 | E22 | published | launch: space | Pikeville, KY | 2024 |
| METROPOLITAN HOSPITAL | $669,759,062 | E22 | published | launch: space | Wyoming, MI | 2024 |
| THE ERIC AND WENDY SCHMIDT FUND FOR STRATEGIC INNOVATION | $406,766,399 | T20 | published | launch: space | Palo Alto, CA | 2024 |
| NATIONAL GALLERY OF ART | $382,850,886 | A51 | published | launch: space | Landover, MD | 2024 |
| NATIONAL GEOGRAPHIC SOCIETY | $340,516,012 | B03 | published | domestic: workers | Washington, DC | 2025 |
| MASS GENERAL BRIGHAM INCORPORATED | $299,721,576 | E21 | published | launch: space | Somerville, MA | 2017 |
| SOUTHEASTERN UNIVERSITIES RESEARCH ASSOCIATION INC | $251,855,977 | U05 | published | launch: space | Washington, DC | 2024 |
| AMERICAN MUSEUM OF NATURAL HISTORY | $246,764,235 | A56 | published | launch: space | New York, NY | 2024 |
| DEBORAH HEART & LUNG CENTER | $239,098,859 | E24 | published | launch: space | Browns Mills, NJ | 2024 |
| WGBH EDUCATIONAL FOUNDATION | $215,642,285 | A30 | published | launch: space | Brighton, MA | 2024 |
| RICHARD KING MELLON FOUNDATION DTD 01-01-47 | $210,921,643 | T20 | published | launch: space | Ligonier, PA | 2024 |
| ARKANSAS COMMUNITY FOUNDATION INC | $159,419,685 | T31 | published | launch: space | Little Rock, AR | 2024 |
| THE AHMANSON FOUNDATION | $143,825,120 | T22 | published | launch: space | Beverly Hills, CA | 2024 |
| AMERICAN SOCIETY FOR TESTING AND MATERIALS | $134,694,228 | U40 | published | launch: space | Conshohocken, PA | 2024 |
| MASS GENERAL BRIGHAM INCORPORATED | $129,616,534 | E21 | published | launch: space | Somerville, MA | 2017 |
| OAKS CHRISTIAN SCHOOL | $90,975,336 | B25 | published | launch: space | Westlake Vlg, CA | 2024 |
| FOR INSPIRATION AND RECOGNITION OF SCIENCE AND TECHNOLOGY FIRST | $84,935,359 | U40 | published | launch: space | Manchester, NH | 2024 |
| UAB MEDICINE ENTERPRISE | $80,343,973 | E99 | published | launch: space | Birmingham, AL | 2024 |
| UNIVERSITY OF IOWA STRATEGIC INITIATIVES FUND | $66,071,839 | B11 | published | launch: space | Iowa City, IA | 2024 |
| MANNED SPACE FLIGHT EDUCATION FOUNDATION INCORPORATED | $61,190,428 | S30 | published | launch: space | Houston, TX | 2024 |
| THE HEISING-SIMONS FOUNDATION | $60,044,121 | T20 | published | launch: space | Los Altos, CA | 2024 |
| FRANKLIN INSTITUTE | $51,159,403 | A25 | published | launch: space | Philadelphia, PA | 2024 |
| UNIVERSITIES SPACE RESEARCH ASSOCIATION | $50,543,825 | U30 | published | launch: space | Washington, DC | 2024 |
| X PRIZE FOUNDATION INC | $47,528,889 | W70 | published | launch: space | Culver City, CA | 2024 |
| HOUSTON SYMPHONY SOCIETY | $45,248,050 | A69 | published | launch: space | Houston, TX | 2024 |
| CAMERON WORKS INC | $43,435,260 | J20 | published | launch: space | Brownsville, TX | 2024 |
| LIBERTY SCIENCE CENTER INC | $39,690,001 | A57 | published | launch: space | Jersey City, NJ | 2024 |
| INTREPID MUSEUM FOUNDATION INC | $39,353,836 | A50 | published | launch: space | New York, NY | 2024 |
| WESTRIDGE SCHOOL FOR GIRLS | $31,504,950 | B25 | inferred 0.90 | launch: space | Pasadena, CA | 2024 |
| MAINE TECHNOLOGY INSTITUTE | $30,490,647 | B29 | published | launch: space | Portland, ME | 2024 |
| AMERICAN HONDA FOUNDATION | $29,551,362 | T21 | inferred 0.70 | launch: space | Torrance, CA | 2025 |
| AEROSPACE INDUSTRIES ASSOCIATION OF AMERICA INC | $28,886,424 | S41 | inferred 0.70 | launch: space | Arlington, VA | 2024 |
| SETI INSTITUTE | $27,357,400 | U31 | published | launch: space | Mountain View, CA | 2024 |
| LEMELSON FOUNDATION | $27,191,988 | T20 | published | launch: space | Portland, OR | 2024 |
| NEWARK MUSEUM ASSOCIATION | $23,750,238 | A50 | published | launch: space | Newark, NJ | 2024 |
| GIRL SCOUTS OF GREATER LOS ANGELES | $23,669,444 | O42 | published | launch: space | Inglewood, CA | 2024 |
| FAIRFIELD COUNTYS COMMUNITY FOUNDATION INC | $21,278,159 | T31 | published | launch: space | Norwalk, CT | 2024 |
| EASTERN CHRISTIAN SCHOOL ASSOCIATION | $21,064,097 | B20 | published | launch: space | North Haledon, NJ | 2024 |
| AKRON COMMUNITY FOUNDATION | $20,297,406 | T31 | published | launch: space | Akron, OH | 2024 |
| GRAND CANYON CONSERVANCY | $17,918,741 | C60 | published | launch: space | Grand Canyon, AZ | 2025 |
| COMPUTER HISTORY MUSEUM | $17,860,375 | A54 | published | launch: space | Mountain View, CA | 2024 |
| CENTER FOR THE ADVANCEMENT OF SCIENCE IN SPACE INC | $17,343,230 | U05 | published | launch: space | Merritt Is, FL | 2024 |
| TIGER WOODS FOUNDATION INC | $16,716,797 | B20 | published | launch: space | Anaheim, CA | 2024 |
| GIRL SCOUTS OF EASTERN MISSOURI INC | $16,484,290 | Z99 | published | launch: space | Saint Louis, MO | 2024 |
| WASHINGTON PAVILION MANAGEMENT INC | $15,361,452 | A20 | published | launch: space | Sioux Falls, SD | 2024 |
| GIRL SCOUTS SAN DIEGO-IMPERIAL COUNCIL INC | $13,226,215 | O42 | published | launch: space | San Diego, CA | 2024 |
| ERIC SCHWARTZ FAM FOUNDATION | $13,206,644 | T22 | published | launch: space | Fairfield, IA | 2024 |
| MADISON ALEXANDER COOPER AND MARTHA ROANE COOPER FOUNDATION | $12,992,344 | T31 | inferred 0.60 | launch: space | Waco, TX | 2024 |
| HOWMET AEROSPACE FOUNDATION | $12,176,983 | T22 | published | launch: space | Pittsburgh, PA | 2024 |
| AMATEUR RADIO DIGITAL COMMUNICATIONS | $10,545,900 | A34 | published | launch: space | San Diego, CA | 2025 |
| CANADA FRANCE HAWAII TELESCOPE CORPORATION | $9,111,323 | B43 | inferred 0.60 | launch: space | Kamuela, HI | 2025 |
| Tiger Woods Foundation Inc | $8,080,163 | B82 | inferred 0.72 | launch: space | Irvine, CA | 2009 |
| BRUCE MUSEUM INC | $7,770,928 | A50 | published | launch: space | Greenwich, CT | 2024 |
| NATIONAL INSTITUTE OF AEROSPACE ASSOCIATES | $7,550,232 | U30 | published | launch: space | Hampton, VA | 2024 |
| SPACE SCIENCE INSTITUTE | $7,238,431 | U32 | published | launch: space | Boulder, CO | 2025 |
| ACADEMY FOR SCIENCE AND DESIGN CHARTER SCHOOL | $6,929,539 | B29 | published | launch: space | Nashua, NH | 2024 |
| YOUNG MENS CHRISTIAN ASSOCIATION OF SAN JOAQUIN COUNTY | $6,892,608 | P27 | published | launch: space | Stockton, CA | 2024 |
| LITTLE KESWICK EDUCATION CORPORATION | $6,638,892 | B20 | published | launch: space | Keswick, VA | 2024 |
| SAN DIEGO AIR & SPACE MUSEUM | $6,632,976 | A57 | published | launch: space | San Diego, CA | 2024 |
| UNITED WAY OF MERCED COUNTY INC | $6,496,223 | T70 | published | launch: space | Merced, CA | 2024 |
| YOUNG MARINES OF THE MARINE CORPS LEAGUE | $6,329,678 | O41 | inferred 0.90 | launch: space | Dumfries, VA | 2024 |
| POWERHOUSE SCIENCE CENTER | $5,962,762 | A50 | published | launch: space | Sacramento, CA | 2024 |
| MARTHA HOLDEN JENNINGS FOUNDATION | $5,870,048 | B99 | inferred 0.60 | launch: space | Cleveland, OH | 2024 |
| MUSEUM OF SCIENCE AND INDUSTRY INC | $5,613,855 | A50 | published | launch: space | Tampa, FL | 2024 |
| COMMUNITY COMMUNICATIONS INC | $5,548,083 | A30 | published | launch: space | Orlando, FL | 2024 |
| YOUNG JUDAEA CAMP SPROUT LAKE | $5,403,834 | O20 | inferred 0.75 | launch: space | Verbank, NY | 2024 |
| AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE AALAS | $5,273,205 | D03 | published | launch: space | Memphis, TN | 2024 |
| BLUE MARBLE SPACE | $5,115,175 | U31 | published | launch: space | Seattle, WA | 2024 |
| GIRL SCOUT COUNCIL OF THE SOUTHERN APPALACHIANS INC | $5,084,614 | O42 | published | launch: space | Knoxville, TN | 2024 |
| CAROL ANN AND RALPH V HAILE JR FOUNDATION | $4,760,971 | T22 | published | launch: space | Covington, KY | 2024 |
| NATIONAL PARK TRUST INC | $4,747,069 | C34 | published | launch: space | Rockville, MD | 2024 |
| OTTUMWA REGIONAL LEGACY FOUNDATION INC | $4,340,730 | E22 | published | launch: space | Ottumwa, IA | 2024 |
| THE ACADEMY RESEARCH AND DEVELOPMENT INSTITUTE | $4,198,912 | B82 | inferred 0.60 | launch: space | Colorado Spgs, CO | 2024 |
| DENVER RESEARCH INSTITUTE | $4,173,308 | E20 | published | launch: space | Denver, CO | 2025 |
| THE TUSKEGEE AIRMEN NATIONAL HISTORICAL MUSEUM | $4,144,625 | A54 | published | launch: space | Detroit, MI | 2025 |
| NORTHERN VIRGINIA TECHNOLOGY COUNCIL INC | $3,495,301 | S41 | inferred 0.70 | launch: space | Falls Church, VA | 2024 |
| TULSA AIR AND SPACE MUSEUM INC | $3,452,594 | A57 | published | launch: space | Tulsa, OK | 2024 |
| LUMEN CLARKE M WILLIAMS FOUNDATION | $3,204,477 | T21 | inferred 0.60 | launch: space | Wilmington, DE | 2024 |
| THE CHALLENGER LEARNNG CENTER OF MAINE | $2,999,137 | B28 | published | launch: space | Bangor, ME | 2024 |
| FRONTIERS OF FLIGHT MUSEUM INC | $2,992,578 | A54 | published | launch: space | Dallas, TX | 2024 |
| NANCY BUCK RANSOM FOUNDATION | $2,983,556 | T22 | inferred 0.60 | launch: space | Monterey, CA | 2024 |
| ST CROIX FOUNDATION FOR COMMUNITY DEVELOPMENT INC | $2,957,162 | T31 | published | launch: space | Christiansted, VI | 2024 |
| AEROSPACE MEDICAL ASSOCIATION | $2,863,645 | G90 | published | launch: space | Alexandria, VA | 2025 |
| DELAWARE AEROSPACE EDUCATION FOUNDATION | $2,637,712 | B90 | published | launch: space | Bear, DE | 2024 |
| ARKANSAS 4-H FOUNDATION INC | $2,611,242 | O52 | published | launch: space | Little Rock, AR | 2024 |
| SCIENCE CLUB FOR GIRLS INC | $2,607,574 | O30 | published | launch: space | Cambridge, MA | 2024 |
| VENTURE FOR AMERICA INC | $2,498,672 | S30 | published | launch: space | Detroit, MI | 2024 |
| CENTER FOR COMPUTATIONAL SCIENCE RESEARCH INC | $2,481,659 | B05 | published | launch: space | River Forest, IL | 2024 |
| NATIONAL SECURITY SPACE ASSOCIATION INC | $2,475,426 | U30 | published | launch: space | Arlington, VA | 2024 |
| WOMEN IN OPHTHALMOLOGY INC | $2,250,432 | E03 | inferred 0.60 | launch: space | San Francisco, CA | 2024 |
| IT TAKES A VILLAGE TO HELP OUR CHILDREN INC | $2,164,509 | I21 | published | launch: space | Crisfield, MD | 2024 |
| FULK FAMILY FOUNDATION INC | $2,144,648 | T22 | inferred 0.75 | launch: space | Chicago, IL | 2024 |
| AEROSPACE AND FLIGHT TEST RADIO COORDINATING COUNCIL INC | $1,975,155 | S40 | published | launch: space | Wichita, KS | 2025 |