| GATES FOUNDATION | $8,084,056,958 | T22 | published | shelter: disaster | Seattle, WA | 2024 |
| PIVOTAL PHILANTHROPIES FOUNDATION | $7,604,936,235 | T22 | published | survivor: sexual | Redmond, WA | 2024 |
| FUND FOR SCIENCE AND TECHNOLOGY | $3,157,814,947 | T22 | published | | Seattle, WA | 2024 |
| THE SUSAN THOMPSON BUFFETT FOUNDATION | $2,731,854,610 | T22 | published | | Omaha, NE | 2025 |
| GOOD VENTURES FOUNDATION | $2,597,571,672 | T22 | published | science: research education | Palo Alto, CA | 2024 |
| MOODY FOUNDATION | $1,432,337,894 | T22 | published | survivor: suicide | Galveston, TX | 2024 |
| THE SAROFIM FOUNDATION | $1,389,259,579 | T22 | inferred 0.60 | science: research education | Houston, TX | 2023 |
| FIDELITY FOUNDATION | $1,327,179,367 | T22 | inferred 0.60 | science: research education | Boston, MA | 2024 |
| PATTERSON FAMILY FOUNDATION | $1,174,628,172 | T22 | inferred 0.60 | men: issues | Kansas City, MO | 2021 |
| SERGEY BRIN FAMILY FOUNDATION | $985,621,463 | T22 | published | shelter: disaster | San Francisco, CA | 2024 |
| PIVOTAL PHILANTHROPIES OPPORTUNITY FOUNDATION | $955,644,953 | T22 | published | | Redmond, WA | 2024 |
| PIVOTAL PHILANTHROPIES PATHWAYS FOU NDATION | $955,633,753 | T22 | published | | Redmond, WA | 2024 |
| PIVOTAL PHILANTHROPIES MOMENTUM FOUNDATION | $955,633,407 | T22 | published | | Redmond, WA | 2024 |
| FOUNDATION TO PROMOTE OPEN SOCIETY | $935,043,439 | T22 | published | domestic: workers | New York, NY | 2024 |
| PAUL M ANGELL FAMILY FOUNDATION | $866,996,211 | T22 | published | | Chicago, IL | 2024 |
| S & G FOUNDATION | $743,968,400 | T22 | published | | Albany, NY | 2024 |
| ALICE L WALTON FOUNDATION | $721,949,474 | T22 | published | shelter: homeless | Bentonville, AR | 2024 |
| THE MA-RAN FOUNDATION | $673,837,712 | T22 | inferred 0.60 | | Atlanta, GA | 2024 |
| CONRAD N HILTON FOUNDATION | $619,701,927 | T22 | published | domestic: workers | Westlake Vlg, CA | 2024 |
| MARCUS FOUNDATION INC | $547,934,030 | T22 | inferred 0.60 | | Atlanta, GA | 2024 |
| GEORGE AND BEVERLY RAWLINGS ENDOWMENT FOUNDATION INC | $543,702,980 | T22 | published | shelter: animal | Lagrange, KY | 2024 |
| ARIE AND IDA CROWN MEMORIAL | $496,729,479 | T22 | inferred 0.60 | | Chicago, IL | 2024 |
| XIE FOUNDATION | $438,452,054 | T22 | published | | Sunnyvale, CA | 2024 |
| ROCKEFELLER FOUNDATION | $415,515,666 | T22 | inferred 0.80 | domestic: workers | New York, NY | 2024 |
| OVERLAKE FUND | $381,589,652 | T22 | inferred 0.50 | science: research education | Burlington, VT | 2024 |
| GREAT HILL PHILANTHROPIC FUND INC | $380,947,148 | T22 | inferred 0.50 | | New York, NY | 2024 |
| JOSEPH B WHITEHEAD FOUNDATION | $352,630,813 | T22 | inferred 0.60 | men: issues | Atlanta, GA | 2025 |
| BEZOS FAMILY FOUNDATION | $352,032,521 | T22 | published | | Seattle, WA | 2024 |
| JAMES IRVINE FOUNDATION | $350,154,179 | T22 | published | domestic: workers | San Francisco, CA | 2024 |
| CRANKSTART FOUNDATION | $348,978,834 | T22 | published | violence: community | San Jose, CA | 2024 |
| THE ARTHUR M BLANK FAMILY FOUNDATION | $331,216,552 | T22 | published | launch: aviation | Atlanta, GA | 2024 |
| WELLSPRING PHILANTROPIC FUND INC | $329,254,342 | T22 | published | space: for men | New York, NY | 2023 |
| THE ESTHER A AND JOSEPH KLINGENSTEIN FUND INC | $329,192,065 | T22 | inferred 0.60 | | New York, NY | 2024 |
| THE BESSEMER GIVING FUND | $311,603,090 | T22 | published | survivor: disaster | Woodbridge, NJ | 2024 |
| FEIGIN FOUNDATION | $309,499,534 | T22 | published | | Wilmington, DE | 2025 |
| JACK JOSEPH AND MORTON MANDEL FOUNDATION | $305,406,910 | T22 | published | | Cleveland, OH | 2024 |
| PETER AND JERI DEJANA FAMILY FOUNDATION | $302,345,806 | T22 | published | shelter: animal | Prt Washingtn, NY | 2024 |
| GOTTESMAN FUND | $279,865,509 | T22 | inferred 0.60 | | New York, NY | 2024 |
| BEDFORD FALLS FOUNDATION | $275,285,562 | T22 | published | | Mclean, VA | 2025 |
| ELISABETH C DELUCA FOUNDATION INC | $264,216,475 | T22 | published | girls boys: boys girls clubs | Pompano Beach, FL | 2024 |
| COLUMBIA LUTHERAN CHARITIES | $257,144,254 | T22 | published | women: issues | Astoria, OR | 2024 |
| JESUS FUND | $251,812,353 | T22 | published | | Little Rock, AR | 2025 |
| BUILDERS INITIATIVE | $245,156,232 | T22 | published | violence: community | Chicago, IL | 2024 |
| STARR FOUNDATION | $233,262,198 | T22 | published | girls boys: girl scouts | New York, NY | 2024 |
| JAMES M COX FOUNDATION OF GA INC | $231,859,375 | T22 | inferred 0.60 | women: issues | Atlanta, GA | 2024 |
| THE@ARHANT SOCIAL FOUNDATION INC | $220,976,043 | T22 | published | shelter: homeless | Clifton, VA | 2024 |
| THE MELLEN CHARITABLE FOUNDATION INC | $220,762,397 | T22 | published | | Boston, MA | 2024 |
| W M KECK FOUNDATION | $220,502,754 | T22 | published | space: outer | Los Angeles, CA | 2024 |
| GERSON BAKAR FOUNDATION | $198,287,464 | T22 | inferred 0.60 | | San Francisco, CA | 2024 |
| BARR FOUNDATION | $191,760,040 | T22 | published | girls boys: boy scouts | Boston, MA | 2024 |
| WATKINS CHRISTIAN FOUNDATION INC | $185,330,052 | T22 | inferred 0.60 | launch: religious | Atlanta, GA | 2025 |
| M J MURDOCK CHARITABLE TRUST | $179,774,834 | T22 | published | girls boys: girl scouts | Vancouver, WA | 2024 |
| PRITZKER FAMILY FOUNDATION | $172,167,164 | T22 | published | science: research education | Chicago, IL | 2024 |
| HAROLD ALFOND FOUNDATION | $171,021,822 | T22 | published | science: research education | Portland, ME | 2024 |
| EDWARD M DOWD FOUNDATION | $167,883,684 | T22 | published | | Monterey, CA | 2025 |
| TUA DAVID & ELAINE MYERS CHAR TR | $162,645,093 | T22 | inferred 0.50 | | Dallas, TX | 2025 |
| ROXANNE AND HENRY BRANDT FOUNDATION | $160,618,755 | T22 | published | | New York, NY | 2023 |
| ROBERTS FOUNDATION | $156,209,074 | T22 | inferred 0.60 | men: issues | San Mateo, CA | 2024 |
| THE ALTA AND JOHN FRANKS FOUNDATION | $150,104,700 | T22 | inferred 0.60 | | Shreveport, LA | 2024 |
| BROWN FOUNDATION INC | $145,856,621 | T22 | published | survivor: disaster | Houston, TX | 2024 |
| THE CALIFORNIA ENDOWMENT | $145,223,990 | T22 | published | space: for men | Los Angeles, CA | 2024 |
| WALLIS ANNENBERG LEGACY FOUNDATION | $143,863,622 | T22 | published | domestic: animals | Playa Vista, CA | 2024 |
| THE AHMANSON FOUNDATION | $143,825,120 | T22 | published | launch: space | Beverly Hills, CA | 2024 |
| STEVEN & ALEXANDRA COHEN FOUNDATION INC | $142,192,267 | T22 | published | women: issues | Stamford, CT | 2024 |
| PRITZKER TRAUBERT FOUNDATION | $141,704,432 | T22 | published | | Chicago, IL | 2024 |
| VAN ANDEL INSTITUTE | $139,332,774 | T22 | published | science: research education | Grand Rapids, MI | 2023 |
| AMK CHARITABLE FOUNDATION | $138,291,389 | T22 | published | women: issues | Henderson, NV | 2024 |
| SUE & EDGAR WACHENHEIM FOUNDATION | $137,996,447 | T22 | inferred 0.85 | | Purchase, NY | 2024 |
| SANDS FAMILY FOUNDATION INC | $131,868,158 | T22 | inferred 0.60 | science: research education | Delray Beach, FL | 2024 |
| GILBERT FAM FOUNDATION | $131,783,494 | T22 | published | | Detroit, MI | 2024 |
| GARY AND MARY WEST CHARITABLE TRUST | $131,725,584 | T22 | published | | La Jolla, CA | 2024 |
| DUNE ROAD FOUNDATION INC | $124,335,186 | T22 | published | | New York, NY | 2024 |
| LAURIE AND REED MORIAN FOUNDATION | $120,958,036 | T22 | published | shelter: homeless | Houston, TX | 2024 |
| DAVIS FAMILY FOUNDATION | $120,684,696 | T22 | published | | Hanover, MD | 2024 |
| OVERDECK FAMILY FOUNDATION | $117,917,796 | T22 | published | | New York, NY | 2024 |
| PAUL E SINGER FOUNDATION | $115,928,576 | T22 | published | | New York, NY | 2023 |
| ENGELSTAD FAM FOUNDATION | $112,969,986 | T22 | published | | Las Vegas, NV | 2024 |
| THE JOHN AND KATHLEEN SCHREIBER FOUNDATION | $112,209,247 | T22 | published | abuse: substance | Lake Forest, IL | 2024 |
| JADER TRUST 4 | $111,692,764 | T22 | inferred 0.50 | science: research education | New York, NY | 2024 |
| THE THOMPSON FAMILY FOUNDATION INC | $109,217,326 | T22 | inferred 0.60 | | New York, NY | 2024 |
| EUGENE B CASEY FOUNDATION | $106,426,026 | T22 | published | women: issues | Gaithersburg, MD | 2024 |
| C D SPANGLER FOUNDATION INC | $106,080,281 | T22 | published | | Charlotte, NC | 2025 |
| FMH FOUNDATION | $104,597,316 | T22 | published | shelter: homeless | Midland, TX | 2024 |
| SAMUELI FOUNDATION | $104,281,760 | T22 | published | science: research education | Corona Dl Mar, CA | 2024 |
| BAUSTERT FAMILY FOUNDATION | $104,185,535 | T22 | published | | Minneapolis, MN | 2025 |
| LETTIE PATE EVANS FOUNDATION INC | $100,913,257 | T22 | inferred 0.60 | girls boys: boys | Atlanta, GA | 2025 |
| TC Family Foundation | $100,392,567 | T22 | inferred 0.50 | | Wilmington, DE | 2025 |
| GUEST HOUSE MINISTRIES FOUNDATION INC | $100,162,435 | T22 | published | | Carlsbad, CA | 2025 |
| ALDARRA FOUNDATION | $100,032,269 | T22 | published | survivor: cancer | Seattle, WA | 2024 |
| RYAN FOUNDATION | $98,564,304 | T22 | inferred 0.70 | | Greenwood Vlg, CO | 2025 |
| JOHN BULOW CAMPBELL FOUNDATION | $98,073,608 | T22 | published | | Atlanta, GA | 2024 |
| THOMAS D KLINGENSTEIN FUND | $95,726,685 | T22 | published | | Cranbury, NJ | 2024 |
| DAVID C BUTTERFIELD AND ALFONSO D RUBIO | $95,550,153 | T22 | inferred 0.60 | | New York, NY | 2023 |
| MUSK FOUNDATION | $94,680,190 | T22 | published | girls boys: girls | Austin, TX | 2024 |
| BROAD FOUNDATION | $89,134,172 | T22 | published | science: research education | Los Angeles, CA | 2024 |
| KARABOTS FOUNDATION | $88,357,942 | T22 | published | | Ft Washington, PA | 2024 |
| THE GRATEFUL LIVES FOUNDATION | $84,765,909 | T22 | published | | Wilmington, DE | 2024 |
| BRISTOL-MYERS SQUIBB FOUNDATION INC | $82,957,469 | T22 | inferred 0.60 | | Princeton, NJ | 2024 |
| GRAY FOUNDATION | $82,515,466 | T22 | published | shelter: homeless | Albany, NY | 2025 |
| SURDNA FOUNDATION INC | $82,509,894 | T22 | published | | New York, NY | 2024 |