| UNIVERSITY OF PITTSBURGH | $3,574,990,567 | B99 | published | | Pittsburgh, PA | 2024 |
| BOEHRINGER INGELHEIM CARES FOUNDATION INC | $2,057,266,961 | B99 | published | | Ridgefield, CT | 2025 |
| CFA INSTITUTE | $534,038,687 | B99 | inferred 0.50 | science: research education | Charlottesvle, VA | 2024 |
| UNIVERSITY MEDICAL SERVICE ASSOCIATION INC | $493,985,662 | B99 | published | | Tampa, FL | 2024 |
| INTERNATIONAL AMERICAN EDUCATION FEDERATION INC | $342,488,403 | B99 | published | | Richardson, TX | 2024 |
| CHARTER INSTITUTE AT ERSKINE | $299,875,169 | B99 | published | | Columbia, SC | 2024 |
| UNIVERSITY OF THE SOUTH | $246,056,453 | B99 | published | science: research education | Sewanee, TN | 2024 |
| SPENCER FOUNDATION | $235,611,615 | B99 | published | space: for women | Chicago, IL | 2024 |
| SUCCESS ACADEMY CHARTER SCHOOLS INC | $187,954,919 | B99 | published | | New York, NY | 2024 |
| STAND TOGETHER TRUST | $172,644,390 | B99 | published | | Arlington, VA | 2024 |
| BASIS CHARTER SCHOOLS INC | $169,474,511 | B99 | published | | Scottsdale, AZ | 2024 |
| WARSZAWSKI UNIWRSYTET MEDYCZNY | $163,852,752 | B99 | published | science: research education | Poland | 2024 |
| BRAVERHOOD LTD | $163,059,998 | B99 | published | | Brooklyn, NY | 2024 |
| KIPP FOUNDATION | $145,514,165 | B99 | published | violence: gun | San Francisco, CA | 2024 |
| FAMILY INC | $132,813,037 | B99 | published | | Louisville, KY | 2025 |
| COORDINATED BEHAVIORAL CARE INC | $128,405,812 | B99 | published | abuse: substance | New York, NY | 2024 |
| KHAN ACADEMY INC | $117,488,956 | B99 | published | science: research education | Mountain View, CA | 2024 |
| UW PHYSICIANS NETWORK | $109,772,223 | B99 | published | | Seattle, WA | 2024 |
| INTERNATIONAL ACADEMY OF SCIENCE | $106,589,066 | B99 | inferred 0.60 | science: research education | Kansas City, MO | 2024 |
| ELECTRONIC CLASSROOM OF TOMORROW | $96,341,668 | B99 | inferred 0.60 | | Columbus, OH | 2016 |
| CHEVRON PHILLIPS CHEMICAL CO LP HEALTH & BENEFIT TR VEBA | $95,107,299 | B99 | published | | Pittsburgh, PA | 2024 |
| EDUCATION SERVICE CENTER REGION XIII | $90,492,548 | B99 | published | | Austin, TX | 2024 |
| MINNESOTA TRANSITIONS CHARTERED SCHOOL | $88,333,286 | B99 | published | | Minneapolis, MN | 2024 |
| CALIFORNIA TEACHING FELLOWS FOUNDATION | $86,970,206 | B99 | inferred 0.70 | | Fresno, CA | 2024 |
| AVID CENTER | $86,402,327 | B99 | published | | San Diego, CA | 2024 |
| INSPIRITEC INC | $83,423,745 | B99 | published | | Philadelphia, PA | 2024 |
| LIFE SCHOOL OF DALLAS | $82,232,699 | B99 | published | | Red Oak, TX | 2024 |
| INSTITUTE OF INTERNAL AUDITORS | $81,792,115 | B99 | inferred 0.50 | | Lake Mary, FL | 2024 |
| LIMESTONE CHARTER ASSOCIATION | $80,123,478 | B99 | inferred 0.60 | | Columbia, SC | 2025 |
| PRAGER UNIVERSITY FOUNDATION | $76,572,101 | B99 | published | | Sherman Oaks, CA | 2025 |
| STRADA COLLABORATIVE INC | $74,422,160 | B99 | inferred 0.60 | | Indianapolis, IN | 2023 |
| JOACHIM HERZ STIFTUNG | $71,812,706 | B99 | inferred 0.60 | science: research education | Greece | 2025 |
| BAKER HALL | $69,906,261 | B99 | published | abuse: sexual | Lackawanna, NY | 2024 |
| UNITED STATES CATHOLIC CONFERENCE | $66,759,960 | B99 | inferred 0.50 | | Burr Ridge, IL | 2024 |
| UNICARE COMMUNITY HEALTH CENTER INC | $65,524,663 | B99 | published | women: issues | Ontario, CA | 2024 |
| SOUTH FLORIDA PREVENTATIVE CARE INITIATIVE INC | $65,183,686 | B99 | published | | Miami, FL | 2024 |
| SOCIAL GOOD FUND INC | $62,018,526 | B99 | published | | Richmond, CA | 2024 |
| SOUTH CAROLINA CONNECTIONS ACADEMY INC | $61,783,234 | B99 | published | | Columbia, SC | 2024 |
| PENNSYLVANIA VIRTUAL CHARTER SCHOOL | $59,530,781 | B99 | published | violence: community | Kng Of Prussa, PA | 2024 |
| FAMILY GUIDANCE CENTERS INC | $56,773,309 | B99 | inferred 0.60 | abuse: substance | Glenview, IL | 2024 |
| GAMECOCK CLUB | $56,433,366 | B99 | published | | Columbia, SC | 2024 |
| GEORGIA ADVANCED TECHNOLOGY VENTURES INC | $56,010,998 | B99 | published | science: research education | Atlanta, GA | 2024 |
| Project Lead the Way Inc | $55,357,801 | B99 | inferred 0.60 | science: research education | Indianapolis, IN | 2018 |
| H E BUTT FOUNDATION | $53,289,623 | B99 | inferred 0.50 | science: research education | Kerrville, TX | 2024 |
| UNDERSTOOD FOR ALL INC | $50,748,062 | B99 | inferred 0.40 | | New York, NY | 2025 |
| NATIONAL ELEVATOR INDUSTRY EDUCATIONAL PROGRAM | $50,223,538 | B99 | inferred 0.60 | | Attleboro Fls, MA | 2024 |
| THE HERON INSTITUTE | $49,941,483 | B99 | published | | Greenville, SC | 2024 |
| TEACH FOR ALL INC | $48,952,741 | B99 | published | | New York, NY | 2024 |
| EASTCONN REGIONAL EDUCATIONAL SERVICE CENTER INCORPORATED | $47,811,046 | B99 | inferred 0.75 | | Hampton, CT | 2023 |
| FOUR LAKES EDUCATION INC | $47,586,293 | B99 | published | | Mcfarland, WI | 2024 |
| CLASSICAL ACADEMY | $47,530,259 | B99 | published | | Colorado Spgs, CO | 2024 |
| EDADVANCE | $46,801,439 | B99 | inferred 0.60 | | Litchfield, CT | 2024 |
| RIVERS SCHOOL CORPORATION | $45,867,933 | B99 | inferred 0.70 | | Weston, MA | 2024 |
| NATIONAL ASSOCIATION OF STATE PROCUREMENT OFFICIALS | $44,029,833 | B99 | published | | Lexington, KY | 2024 |
| PROTEUS FUND INC | $43,200,431 | B99 | published | science: research education | Waltham, MA | 2024 |
| PLATO ACADEMY SCHOOLS CORPORATION | $43,120,577 | B99 | published | | Clearwater, FL | 2024 |
| REACH UNIVERSITY | $42,968,630 | B99 | published | | Oakland, CA | 2024 |
| WEST VIRGINIA UNIVERSITY MEDICAL CORPORATION | $42,008,843 | B99 | published | science: research education | Charleston, WV | 2023 |
| HALO NETWORK INC | $41,008,566 | B99 | published | | Amityville, NY | 2025 |
| ARKANSAS CONNECTIONS ACADEMY INC | $40,332,117 | B99 | published | | Bentonville, AR | 2024 |
| AUSTIN ACHIEVE PUBLIC SCHOOLS INC | $39,544,345 | B99 | published | | Austin, TX | 2024 |
| NATIONAL CENTER FOR RESEARCH IN ADVANCED | $38,475,850 | B99 | inferred 0.55 | launch: launch | Washington, DC | 2019 |
| AFTER-SCHOOL ALL-STARS LOS ANGELES | $38,250,910 | B99 | published | violence: community | Los Angeles, CA | 2024 |
| RITE OF PASSAGE ADOLESCENT TREATMENT CENTERS AND SCHOOLS INC | $37,038,313 | B99 | inferred 0.50 | survivor: sexual | Minden, NV | 2024 |
| LIFESTEPS INC | $36,390,415 | B99 | published | abuse: child | Butler, PA | 2024 |
| ALL FOR HEALTH HEALTH FOR ALL INC | $36,248,123 | B99 | published | women: issues | Glendale, CA | 2024 |
| OLD DOMINION LAND CONSERVANCY INC | $35,994,162 | B99 | published | science: research education | Purcellville, VA | 2025 |
| LATINOS SALUD INC | $34,747,878 | B99 | published | men: issues | Wilton Manors, FL | 2025 |
| COLLEGE POSSIBLE | $34,574,024 | B99 | published | | Saint Paul, MN | 2024 |
| FACULTY ASSOCIATES INCORPORATED | $33,582,405 | B99 | published | science: research education | Gainesville, FL | 2024 |
| EARLY LEARNING COALITION OF OSCEOLA COUNTY INC | $32,749,934 | B99 | published | | Kissimmee, FL | 2024 |
| AMERICAN HEALTH INFORMATION MANAGEMENT ASSOCIATION | $32,550,697 | B99 | inferred 0.50 | | Chicago, IL | 2024 |
| EL EDUCATION INC | $32,254,976 | B99 | published | | New York, NY | 2024 |
| BOSTON PLASTIC & ORAL SURGERY FOUNDATION INC | $32,249,728 | B99 | published | science: research education | Boston, MA | 2024 |
| COMP-U-DOPT INC | $31,298,169 | B99 | published | space: outer | Houston, TX | 2024 |
| LSNY BRONX CORPORATION | $31,276,771 | B99 | published | abuse: child | New York, NY | 2024 |
| DENVER SCHOLARSHIP FOUNDATION | $29,852,401 | B99 | published | | Denver, CO | 2024 |
| Measured Progress Inc | $29,790,166 | B99 | inferred 0.50 | | Dover, NH | 2018 |
| LEARNING TREE INC | $29,506,300 | B99 | inferred 0.60 | | Mobile, AL | 2024 |
| HERITAGE HALL SCHOOL INC | $28,726,874 | B99 | published | | Oklahoma City, OK | 2024 |
| CAL RIPKEN SR FOUNDATION INC | $28,438,019 | B99 | published | science: research education | Baltimore, MD | 2024 |
| PARTNERSHIP FOR LOS ANGELES SCHOOLS | $28,310,878 | B99 | published | | Los Angeles, CA | 2024 |
| XILIN ASSOCIATION | $28,153,204 | B99 | inferred 0.45 | | Lisle, IL | 2025 |
| NATIONAL ASSOCIATION OF INDEPENDENT SCHOOLS INC | $27,311,841 | B99 | inferred 0.60 | | Washington, DC | 2024 |
| FUTURE BUSINESS LEADERS OF AMERICA PHI BETA LAMBDA INC | $27,206,756 | B99 | inferred 0.60 | | Reston, VA | 2024 |
| SCHOOL OF EXCELLENCE IN EDUCATION | $27,082,733 | B99 | published | | Chandler, AZ | 2024 |
| UNIVERSITY STUDIES ABROAD CONSORTIUM | $26,613,309 | B99 | published | | Reno, NV | 2024 |
| AMERICAN SOCIETY FOR ENGINEERING EDUCATION | $26,373,548 | B99 | inferred 0.60 | space: outer | Washington, DC | 2024 |
| ARRAY EDUCATION INC | $26,095,528 | B99 | published | science: research education | New York, NY | 2024 |
| HUMAN-I-T | $25,932,526 | B99 | inferred 0.50 | | Bell, CA | 2024 |
| EARLY LEARNING COALITION OF NORTHWEST FLORIDA INC | $25,740,527 | B99 | published | | Marianna, FL | 2024 |
| SUSAN B ANTHONY LIST INC | $25,704,964 | B99 | published | science: research education | Arlington, VA | 2024 |
| KAI MING INC | $25,630,226 | B99 | inferred 0.70 | | San Francisco, CA | 2024 |
| Startup Education | $25,463,866 | B99 | inferred 0.70 | | Mountain View, CA | 2016 |
| INSTRUCTION PARTNERS | $25,314,943 | B99 | published | | Nashville, TN | 2024 |
| OXFORD PREPARATORY ACADEMY | $25,264,403 | B99 | published | | Aliso Viejo, CA | 2024 |
| WISCONSIN EARLY CHILDHOOD ASSOCIATION INC | $25,186,491 | B99 | inferred 0.60 | women: issues | Fitchburg, WI | 2024 |
| R CLUB CHILD CARE INC | $25,094,285 | B99 | inferred 0.60 | | St Petersburg, FL | 2024 |
| TREE OF KNOWLEDGE LEARNING ACADEMY INC | $25,036,365 | B99 | published | | Miami, FL | 2024 |
| ASSOCIATION FOR DIAGNOSTICS & LABORATORY MEDICINE INC | $24,832,682 | B99 | published | science: research education | Washington, DC | 2024 |