| UC HEALTHCARE SYSTEM | $2,926,481,065 | E99 | published | | Cincinnati, OH | 2024 |
| INDEPENDENT HEALTH ASSOCIATION INC | $1,732,719,902 | E99 | published | science: research education | Buffalo, NY | 2024 |
| STRATACOR | $1,239,267,986 | E99 | inferred 0.60 | science: research education | Minneapolis, MN | 2024 |
| HEALTHWELL FOUNDATION | $911,501,566 | E99 | published | | Rockville, MD | 2024 |
| DELTA DENTAL OF MISSOURI | $805,510,567 | E99 | inferred 0.55 | science: research education | St Louis, MO | 2024 |
| MARTINS POINT GENERATIONS ADVANTAGE INC | $745,845,935 | E99 | published | | Portland, ME | 2024 |
| TEXAS HEALTH PHYSICIANS GROUP | $643,463,569 | E99 | published | women: issues | Dallas, TX | 2024 |
| PAHS Service Corporation | $561,568,967 | E99 | inferred 0.45 | | Greenwood Village, CO | 2024 |
| DELTA DENTAL PLAN OF NEW HAMPSHIRE | $497,017,089 | E99 | inferred 0.55 | | Concord, NH | 2024 |
| COMMON GROUND HEALTHCARE COOPERATIVE | $439,395,684 | E99 | published | | Brookfield, WI | 2024 |
| SB CLINICAL PRACTICE MANAGEMENT PLAN INC | $326,714,943 | E99 | published | | Stony Brook, NY | 2024 |
| ASSISTANCE FUND INC | $284,709,120 | E99 | published | | Orlando, FL | 2025 |
| RUSH SYSTEM FOR HEALTH | $283,154,871 | E99 | published | | Chicago, IL | 2024 |
| LEESAR INC | $279,388,563 | E99 | inferred 0.50 | | Fort Myers, FL | 2024 |
| DELTA DENTAL OF IOWA | $261,995,246 | E99 | inferred 0.55 | science: research education | Johnston, IA | 2024 |
| PHILADELPHIA HEALTH & EDUCATION CORP | $261,255,353 | E99 | inferred 0.50 | science: research education | Philadelphia, PA | 2013 |
| DISTRICT MEDICAL GROUP INC | $261,124,428 | E99 | published | abuse: sexual | Phoenix, AZ | 2024 |
| PHOEBE PHYSICIAN GROUP INC | $245,159,199 | E99 | published | | Albany, GA | 2024 |
| PATIENT ACCESS NETWORK FOUNDATION | $230,809,794 | E99 | inferred 0.60 | | Washington, DC | 2025 |
| GENZYME CHARITABLE FOUNDATION INC | $224,152,596 | E99 | inferred 0.60 | | Morristown, NJ | 2024 |
| Banner Health Plan Inc | $214,827,195 | E99 | inferred 0.60 | | Phoenix, AZ | 2024 |
| HOPEHEALTH INC | $200,494,402 | E99 | published | abuse: substance | Florence, SC | 2024 |
| THE SUBSIDIARIES OF THE INSTITUTE | $181,317,847 | E99 | inferred 0.60 | girls boys: girls | Pittsburgh, PA | 2019 |
| DONOR NETWORK WEST | $160,567,000 | E99 | inferred 0.60 | | San Ramon, CA | 2024 |
| CALIFORNIA HEALTHCARE FOUNDATION | $137,311,491 | E99 | inferred 0.55 | abuse: elder | Oakland, CA | 2024 |
| ORGAN PROCUREMENT AGENCY OF MICHIGAN | $135,537,058 | E99 | inferred 0.80 | | Ann Arbor, MI | 2025 |
| FOUNDATION MEDICAL PARTNERS INC | $134,033,925 | E99 | published | | Nashua, NH | 2024 |
| SMILE TRAIN INC | $121,687,237 | E99 | inferred 0.70 | | New York, NY | 2024 |
| OWENSBORO HEALTH MEDICAL GROUP INC | $120,382,638 | E99 | published | | Owensboro, KY | 2024 |
| NORDX | $118,490,275 | E99 | published | | Scarborough, ME | 2024 |
| APLA HEALTH & WELLNESS | $116,451,685 | E99 | published | abuse: substance | Los Angeles, CA | 2024 |
| BALTIMORE WASHINGTON HEALTHCARE SERVICES INC | $106,693,385 | E99 | inferred 0.40 | | Linthicum Heights, MD | 2024 |
| LONG ISLAND JEWISH MEDICAL CENTER AT HOME PHARMACY INC | $105,455,427 | E99 | published | | Westbury, NY | 2024 |
| SIGNAL BEHAVIORAL HEALTH NETWORK | $100,605,935 | E99 | published | abuse: substance | Greenwood Vlg, CO | 2024 |
| NEW ENGLAND ORGAN BANK INC | $99,433,812 | E99 | inferred 0.60 | | Waltham, MA | 2024 |
| AVERA AT HOME | $88,211,233 | E99 | published | | Sioux Falls, SD | 2024 |
| NO AIDS TASK FORCE | $88,042,103 | E99 | inferred 0.50 | abuse: substance | New Orleans, LA | 2024 |
| LIFECENTER NORTHWEST | $85,426,799 | E99 | published | | Bellevue, WA | 2024 |
| UAB MEDICINE ENTERPRISE | $80,343,973 | E99 | published | launch: space | Birmingham, AL | 2024 |
| UNITED NETWORK FOR ORGAN SHARING | $76,646,659 | E99 | inferred 0.60 | science: research education | Richmond, VA | 2024 |
| INTERNATIONAL MEDICAL RELIEF | $76,386,847 | E99 | published | | Denver, CO | 2024 |
| HOSPICE OF CINCINNATI INCORPORATED | $75,546,967 | E99 | inferred 0.60 | | Cincinnati, OH | 2024 |
| DELTA DENTAL PLAN OF NEW MEXICO INC | $74,607,985 | E99 | inferred 0.60 | | Okemos, MI | 2024 |
| MEDSTAR HEALTH RESEARCH INSTITUTE INC | $74,089,762 | E99 | inferred 0.80 | science: research education | Columbia, MD | 2024 |
| FRASER CHILD AND FAMILY CENTER | $71,075,400 | E99 | published | abuse: child | Richfield, MN | 2024 |
| DELTA DENTAL OF RHODE ISLAND | $69,698,652 | E99 | inferred 0.60 | | Providence, RI | 2024 |
| TEMPLE PHYSICIANS INC | $69,541,124 | E99 | published | | Philadelphia, PA | 2024 |
| EMORY UNIVERSITY | $65,388,139 | E99 | published | science: research education | Atlanta, GA | 2009 |
| CIVICA INC | $64,992,602 | E99 | inferred 0.40 | | Lehi, UT | 2024 |
| NATIONAL ASSOCIATION OF CHILDRENS HOSPITAL AND RELATED INSTITUTIONS | $64,966,463 | E99 | inferred 0.55 | abuse: child | Washington, DC | 2025 |
| NAPERVILLE PSYCHIATRIC VENTURES | $63,917,095 | E99 | published | abuse: substance | Arlington Hts, IL | 2024 |
| NETWORK FOR HOPE INC | $61,502,093 | E99 | inferred 0.60 | | Louisville, KY | 2024 |
| SYNOVUS FINANCIAL CORP MEDICAL & | $60,231,547 | E99 | inferred 0.60 | | Columbus, GA | 2024 |
| PIPE TRADES INDUSTRY HEALTH & WELFARE PLAN | $57,865,010 | E99 | inferred 0.60 | | Terre Haute, IN | 2024 |
| UCARE HEALTH INC | $57,617,276 | E99 | published | | Stuart, VA | 2025 |
| NATIONAL COMPREHENSIVE CANCER NETWORK INC | $55,716,889 | E99 | published | | Plymouth Mtng, PA | 2024 |
| FIDELITY HEALTH CARE INC | $54,746,957 | E99 | published | women: issues | Moraine, OH | 2024 |
| MEDICAL SERVICES OF BELLMORE PC | $53,767,051 | E99 | published | | Westbury, NY | 2024 |
| JOHNSON & JOHNSON PATIENT ASSISTANCE FOUNDATION INC | $52,649,489 | E99 | published | | New Brunswick, NJ | 2025 |
| ST JOSEPHS HOSPITAL OF TAMPA FOUNDATION INC | $52,416,525 | E99 | published | survivor: cancer | Tampa, FL | 2024 |
| DELTA DENTAL PLAN OF WYOMING | $51,759,116 | E99 | inferred 0.70 | | Cheyenne, WY | 2024 |
| JOHNS HOPKINS HOME CARE GROUP INC | $51,360,201 | E99 | inferred 0.60 | | Baltimore, MD | 2024 |
| SIGN FRACTURE CARE INTERNATIONAL | $51,354,803 | E99 | published | violence: community | Richland, WA | 2025 |
| HOSPICE OF THE CHESAPEAKE | $50,836,964 | E99 | inferred 0.80 | | Pasadena, MD | 2024 |
| ARCHBOLD MEDICAL CENTER INC | $50,062,015 | E99 | inferred 0.60 | | Thomasville, GA | 2024 |
| MCAULEY-SETON HOME CARE INC | $49,787,680 | E99 | published | | Buffalo, NY | 2024 |
| JPS PHYSICIAN GROUP INC | $49,740,916 | E99 | inferred 0.60 | science: research education | Fort Worth, TX | 2012 |
| AMERICAN CANCER SOCIETY INC PENNSYLVANIA | $49,201,676 | E99 | inferred 0.90 | survivor: cancer | Hershey, PA | 2009 |
| FRONT RANGE HEALTH PARTNERS LLC | $48,986,213 | E99 | published | | Wheat Ridge, CO | 2023 |
| GREATER FAMILY HEALTH | $48,036,267 | E99 | published | | Hoffman Estates, IL | 2024 |
| SPECIAL HEALTH RESOURCES FOR TEXAS INCORPORATED | $47,920,856 | E99 | inferred 0.60 | abuse: substance | Longview, TX | 2024 |
| LIFESHARE BLOOD CENTER | $47,726,980 | E99 | inferred 0.80 | science: research education | Shreveport, LA | 2025 |
| WHOLE FAMILY HEALTH CENTER INC | $46,443,610 | E99 | published | | Vero Beach, FL | 2024 |
| MENTAL HEALTH RESOURCE CENTER INC | $45,900,158 | E99 | published | | Jacksonville, FL | 2024 |
| HORIZON HOME CARE & HOSPICE INC | $45,521,767 | E99 | published | women: issues | Milwaukee, WI | 2024 |
| HEALTH FORWARD FOUNDATION | $45,105,484 | E99 | published | violence: gun | Kansas City, MO | 2024 |
| CARE RESOURCES | $44,971,314 | E99 | published | | Grand Rapids, MI | 2024 |
| CHILDRENS SPORT MEDICINE FOUNDATION INC | $44,493,692 | E99 | inferred 0.60 | science: research education | Boston, MA | 2024 |
| AMERICAN COLLEGE OF EMERGENCY PHYSICIANS | $43,330,183 | E99 | inferred 0.60 | | Irving, TX | 2024 |
| NEIGHBORHOOD HEALTH CENTER | $43,039,213 | E99 | published | | Portland, OR | 2024 |
| SOUTHEASTERN LOUISIANA AREA HEALTH EDUCATION CENTER | $41,792,774 | E99 | inferred 0.50 | women: issues | Hammond, LA | 2024 |
| DELTA DENTAL PLANS ASSOCIATION | $41,529,392 | E99 | inferred 0.50 | | Chicago, IL | 2024 |
| UPSTATE NEW YORK TRANSPLANT SERVICES INC | $41,519,206 | E99 | inferred 0.60 | | Williamsville, NY | 2025 |
| TEXAS ORGAN SHARING ALLIANCE | $40,783,517 | E99 | inferred 0.60 | | San Antonio, TX | 2024 |
| American Cancer Society Inc Illinois | $39,665,767 | E99 | inferred 0.60 | survivor: cancer | Chicago, IL | 2011 |
| HUNTERDON PRIMARY CARE PC | $38,592,899 | E99 | inferred 0.55 | | Flemington, NJ | 2024 |
| CAMERON MEDICAL OUTREACH INC | $38,148,387 | E99 | published | | Angola, IN | 2024 |
| KENTUCKY HOSPITAL ASSOCIATION | $37,655,065 | E99 | inferred 0.50 | abuse: substance | Louisville, KY | 2024 |
| AMERICAN COLLEGE OF RHEUMATOLOGY | $37,209,245 | E99 | inferred 0.60 | science: research education | Atlanta, GA | 2024 |
| AMERICAN SOCIETY OF NEPHROLOGY INC | $36,768,596 | E99 | inferred 0.60 | science: research education | Washington, DC | 2025 |
| LOVELACE BIOMEDICAL & ENVIRONMENTAL | $36,706,942 | E99 | inferred 0.60 | science: research education | Albuquerque, NM | 2018 |
| DIMENSIONS HEALTHCARE ASSOCIATES | $35,372,036 | E99 | published | | Linthicum Heights, MD | 2024 |
| PIKE HEALTH SERVICES INC | $35,114,677 | E99 | published | | Waverly, OH | 2024 |
| AMERICAN ACADEMY OF PHYSICIAN ASSOCIATES INC | $35,021,068 | E99 | inferred 0.50 | | Alexandria, VA | 2025 |
| NATIONAL ORGANIZATION FOR RARE DISORDERS INC | $34,577,196 | E99 | inferred 0.60 | science: research education | Danbury, CT | 2025 |
| EASTERSEALS NORTHERN CALIFORNIA | $34,269,397 | E99 | published | shelter: animal | Walnut Creek, CA | 2025 |
| HOSPICE OF THE TREASURE COAST INC | $32,871,818 | E99 | inferred 0.60 | | Stuart, FL | 2024 |
| GIFT OF LIFE MARROW REGISTRY INC | $31,920,517 | E99 | published | science: research education | Boca Raton, FL | 2024 |
| ILLINOIS HEALTH AND HOSPITAL ASSOCIATION | $31,713,571 | E99 | inferred 0.60 | | Naperville, IL | 2025 |
| UNIVERSITY HOSPITALS HEALTH SYSTEM INC | $31,677,804 | E99 | published | women: issues | Shaker Hts, OH | 2021 |