| BATTELLE MEMORIAL INSTITUTE | $13,526,408,187 | U20 | published | science: research education | Columbus, OH | 2024 |
| ADVANCED TECHNOLOGY INTERNATIONAL | $4,870,021,886 | U99 | published | science: research education | Summerville, SC | 2024 |
| THE MITRE CORPORATION | $2,475,879,129 | U40 | published | science: research education | Bedford, MA | 2024 |
| AEROSPACE CORPORATION | $1,623,067,000 | U30 | published | launch: space | Chantilly, VA | 2024 |
| RESEARCH TRIANGLE INSTITUTE | $1,254,259,534 | U20 | published | science: research education | Rtp, NC | 2024 |
| ALLIANCE FOR ENERGY INNOVATION LLC | $1,064,585,917 | U05 | published | science: research education | Golden, CO | 2024 |
| COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION | $1,034,784,608 | U20 | inferred 0.80 | science: research education | San Francisco, CA | 2024 |
| SOUTHWEST RESEARCH INSTITUTE | $978,595,721 | U99 | published | space: outer | San Antonio, TX | 2024 |
| CHARLES STARK DRAPER LABORATORY INC | $949,348,102 | U40 | published | launch: space | Cambridge, MA | 2024 |
| WEIZMANN INSTITUTE OF SCIENCE | $891,074,542 | U50 | published | | Israel | 2024 |
| AMERICAN CHEMICAL SOCIETY | $819,099,460 | U33 | published | launch: launch | Washington, DC | 2024 |
| BLUEFORGE ALLIANCE | $731,167,389 | U40 | published | science: research education | Bryan, TX | 2024 |
| FERMI FORWARD DISCOVERY GROUP LLC | $645,523,193 | U99 | published | science: research education | Batavia, IL | 2024 |
| NOBLIS INC | $614,468,693 | U20 | published | space: outer | Reston, VA | 2024 |
| AMERICAN BUREAU OF SHIPPING | $536,588,479 | U30 | inferred 0.50 | | Spring, TX | 2024 |
| ASSOCIATION OF UNIVERSITIES FOR | $468,809,827 | U31 | published | space: outer | Washington, DC | 2024 |
| SRI INTERNATIONAL | $437,926,151 | U20 | published | space: outer | Menlo Park, CA | 2024 |
| NATIONAL ACADEMY OF SCIENCES | $361,712,009 | U03 | published | science: research education | Washington, DC | 2024 |
| CLIMATEWORKS FOUNDATION | $350,641,228 | U12 | published | launch: launch | San Francisco, CA | 2024 |
| INSTITUTE FOR DEFENSE ANALYSES | $344,675,047 | U05 | published | science: research education | Alexandria, VA | 2024 |
| WOODS HOLE OCEANOGRAPHIC INSTITUTION | $344,338,772 | U21 | published | science: research education | Woods Hole, MA | 2024 |
| UNIVERSITY CORPORATION FOR ATMOSPHERIC RESEARCH | $288,690,542 | U30 | published | | Boulder, CO | 2024 |
| Aleo Network Foundation | $260,535,815 | U20 | inferred 0.50 | | Cheyenne, WY | 2024 |
| ALFRED E MANN FOUNDATION FOR SCIENTIFIC RESEARCH | $257,887,615 | U20 | published | science: research education | Santa Clarita, CA | 2025 |
| SOUTHEASTERN UNIVERSITIES RESEARCH ASSOCIATION INC | $251,855,977 | U05 | published | launch: space | Washington, DC | 2024 |
| MEDICAL TECHNOLOGY ENTERPRISE CONSORTIUM | $234,472,156 | U05 | published | science: research education | N Bethesda, MD | 2024 |
| COLD SPRING HARBOR LABORATORY | $232,693,889 | U50 | published | science: research education | Cold Spg Hbr, NY | 2024 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH INC | $220,648,490 | U05 | published | | Lawrence, KS | 2024 |
| NATIONAL SPECTRUM CONSORTIUM INC | $212,726,410 | U01 | published | | Washington, DC | 2024 |
| THE ALLEN INSTITUTE FOR ARTIFICIAL INTELLIGENCE | $205,844,739 | U50 | published | science: research education | Seattle, WA | 2024 |
| AMERICAN TYPE CULTURE COLLECTION | $198,027,310 | U50 | published | science: research education | Manassas, VA | 2024 |
| PREPASS SAFETY ALLIANCE | $196,625,833 | U40 | published | | Phoenix, AZ | 2024 |
| DEFENSEWERX INC | $195,761,877 | U40 | published | science: research education | Niceville, FL | 2024 |
| INTERNET CORPORATION FOR ASSIGNED NAMES AND NUMBERS | $194,948,725 | U99 | published | | Los Angeles, CA | 2024 |
| SALK INSTITUTE FOR BIOLOGICAL STUDIES | $181,393,442 | U50 | published | men: issues | La Jolla, CA | 2024 |
| THE HAWAII PACIFIC FOUNDATION INC | $173,736,286 | U40 | published | abuse: substance | Honolulu, HI | 2023 |
| FERMI RESEARCH ALLIANCE LLC | $168,510,542 | U02 | published | space: outer | Batavia, IL | 2024 |
| BANK OF SWEDEN TERCENTENARY FOUNDATION | $161,339,017 | U20 | inferred 0.60 | science: research education | Atlanta, GA | 2024 |
| CNA CORPORATION | $154,356,745 | U05 | inferred 0.80 | abuse: substance | Arlington, VA | 2024 |
| THE HIGH Q FOUNDATION INC | $152,192,779 | U99 | published | science: research education | Roseland, NJ | 2023 |
| ASSOCIATED UNIVERSITIES INC | $145,098,658 | U99 | published | space: outer | Vienna, VA | 2024 |
| NY CREATES | $144,806,088 | U40 | published | science: research education | Albany, NY | 2024 |
| ANALYTIC SERVICES INC | $142,473,079 | U40 | published | science: research education | Arlington, VA | 2024 |
| AMERICAN SOCIETY OF MECHANICAL ENGINEERS | $136,989,570 | U03 | published | women: issues | New York, NY | 2024 |
| NATIONAL ADVANCED MOBILITY CONSORTIUM | $135,705,794 | U40 | published | | Ann Arbor, MI | 2024 |
| AMERICAN SOCIETY FOR TESTING AND MATERIALS | $134,694,228 | U40 | published | launch: space | Conshohocken, PA | 2024 |
| AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE | $129,476,881 | U03 | published | launch: launch | Washington, DC | 2024 |
| INSTITUTE OF GAS TECHNOLOGY | $124,247,894 | U33 | published | science: research education | Des Plaines, IL | 2024 |
| NATIONAL CENTER FOR DEFENSE MANUFACTURING AND MACHINING | $119,433,940 | U40 | published | science: research education | Johnstown, PA | 2024 |
| MRIGLOBAL | $115,849,749 | U20 | published | science: research education | Kansas City, MO | 2024 |
| RENAISSANCE PHILANTHROPY FUND | $115,242,559 | U12 | published | | New York, NY | 2025 |
| CONVERGENT RESEARCH INC | $112,676,584 | U05 | published | | Cambridge, MA | 2025 |
| CARNEGIE INSTITUTION OF WASHINGTON | $106,544,070 | U31 | published | space: outer | Washington, DC | 2024 |
| PUBLIC INTEREST REGISTRY | $106,377,555 | U05 | published | abuse: sexual | Reston, VA | 2024 |
| AMERICAN PHYSICAL SOCIETY | $106,332,062 | U03 | published | science: research education | College Park, MD | 2024 |
| CONCURRENT TECHNOLOGIES CORPORATION | $101,274,766 | U40 | published | space: outer | Johnstown, PA | 2024 |
| ASSOCIATION FOR COMPUTING MACHINERY INC | $96,182,576 | U03 | published | science: research education | New York, NY | 2024 |
| SAE INTERNATIONAL | $95,057,958 | U03 | published | space: outer | Warrendale, PA | 2024 |
| AMERICAN INSTITUTE OF PHYSICS INCORPORATED | $92,366,805 | U03 | published | science: christian science | College Park, MD | 2024 |
| SOCIETY FOR SCIENCE AND THE PUBLIC | $91,128,420 | U03 | published | science: research education | Washington, DC | 2024 |
| INSTITUTE FOR ADVANCED STUDY | $88,930,858 | U05 | published | space: outer | Princeton, NJ | 2024 |
| INTERNATIONAL INFORMATION SYSTEM SECURITY CERTIFICATION CONSORTIUM | $87,659,863 | U41 | inferred 0.45 | | Alexandria, VA | 2025 |
| MONTEREY BAY AQUARIUM RESEARCH INSTITUTE | $86,286,917 | U21 | inferred 0.70 | science: research education | Moss Landing, CA | 2024 |
| FOR INSPIRATION AND RECOGNITION OF SCIENCE AND TECHNOLOGY FIRST | $84,935,359 | U40 | published | launch: space | Manchester, NH | 2024 |
| MOTE MARINE LABORATORY | $83,003,369 | U21 | inferred 0.80 | space: outer | Sarasota, FL | 2024 |
| PARALLAX ADVANCED RESEARCH CORP | $82,994,226 | U05 | published | science: research education | Beavercrk Twp, OH | 2024 |
| UNIVERSITY CORPORATION FOR ADVANCED INTERNET DEVELOPMENT | $81,580,045 | U41 | published | science: research education | Ann Arbor, MI | 2024 |
| INTER-INDUSTRY CONFERENCE ON AUTO COLLISION REPAIRS | $79,722,947 | U99 | inferred 0.50 | | Hoffman Est, IL | 2025 |
| PERIMETER INSTITUTE | $79,088,458 | U34 | inferred 0.60 | science: research education | Waterloo, ON | 2024 |
| CABLE TELEVISION LABORATORIES INC | $75,552,254 | U20 | inferred 0.55 | | Louisville, CO | 2024 |
| MCNC | $74,135,271 | U40 | published | science: research education | R Triangle Park, NC | 2024 |
| US CIVILIAN RESEARCH AND DEVELOPMENT FOUNDATION | $73,586,507 | U12 | published | science: research education | Arlington, VA | 2024 |
| ASTERA INSTITUTE | $72,283,069 | U41 | published | science: research education | Berkeley, CA | 2024 |
| SOCIETY OF PHOTO OPTICAL INSTRUMENTATION ENGINEER | $64,378,785 | U03 | inferred 0.80 | space: outer | Bellingham, WA | 2025 |
| UNMC SCIENCE RESEARCH FUND | $64,068,869 | U12 | published | science: research education | Omaha, NE | 2024 |
| DONALD DANFORTH PLANT SCIENCE CENTER | $63,779,784 | U50 | published | girls boys: girl scouts | Saint Louis, MO | 2024 |
| CONSORTIUM FOR ENERGY ENVIRONMENT AND | $62,964,398 | U99 | inferred 0.70 | science: research education | Washington, DC | 2016 |
| GORDON RESEARCH CONFERENCES | $62,035,304 | U33 | published | science: research education | E Greenwich, RI | 2024 |
| GENEVA FOUNDATION 04-15-93 | $60,848,687 | U20 | published | | Tacoma, WA | 2024 |
| AMERICAN SOCIETY OF CIVIL ENGINEERS | $58,896,001 | U03 | published | launch: launch | Reston, VA | 2024 |
| CUBRC INC | $57,021,409 | U32 | published | space: outer | Buffalo, NY | 2024 |
| HUGO W MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER INC | $56,806,410 | U00 | published | science: research education | Baltimore, MD | 2024 |
| AMERICAN GEOPHYSICAL UNION | $56,165,227 | U30 | published | space: outer | Washington, DC | 2024 |
| MARINE BIOLOGICAL LABORATORY | $55,357,167 | U50 | published | science: research education | Woods Hole, MA | 2024 |
| EXPERIMENTAL AIRCRAFT ASSOCIATION INC | $53,861,538 | U03 | published | science: research education | Oshkosh, WI | 2024 |
| FLEXTECH ALLIANCE INC | $53,154,211 | U03 | inferred 0.80 | | San Jose, CA | 2024 |
| HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY | $52,208,987 | U99 | published | science: research education | Huntsville, AL | 2024 |
| SANTA FE INSTITUTE | $51,822,371 | U20 | published | science: research education | Santa Fe, NM | 2024 |
| AMERICAN SOCIETY FOR MICROBIOLOGY | $51,295,584 | U03 | published | science: research education | Washington, DC | 2024 |
| UNIVERSITIES SPACE RESEARCH ASSOCIATION | $50,543,825 | U30 | published | launch: space | Washington, DC | 2024 |
| SOUTHERN RESEARCH INSTITUTE | $50,381,130 | U33 | published | space: outer | Birmingham, AL | 2024 |
| AMERICAN INSTITUTE OF CHEMICAL ENGINEERS | $49,732,128 | U03 | inferred 0.60 | | New York, NY | 2024 |
| WATERFORD INSTITUTE INC | $48,299,857 | U41 | published | science: research education | Taylorsville, UT | 2024 |
| NORTHWEST INSTITUTE OF RESEARCH INC | $47,440,023 | U20 | inferred 0.60 | science: research education | Erie, PA | 2024 |
| GMTO CORPORATION | $46,688,213 | U31 | published | space: outer | Pasadena, CA | 2024 |
| NATIONAL COUNCIL OF EXAMINERS FOR ENGINEERING AND SURVEYING | $45,696,211 | U42 | published | | Greenville, SC | 2024 |
| THE MATH LEARNING CENTER | $44,731,389 | U34 | published | science: research education | Salem, OR | 2024 |
| AMPP GLOBAL CENTER INC | $44,631,316 | U20 | inferred 0.60 | | Houston, TX | 2024 |
| ALTARUM INSTITUTE | $43,405,911 | U05 | published | abuse: substance | Novi, MI | 2024 |
| AMERICAN LIGHTWEIGHT MATERIALS MANUFACTURING INNOVATION INSTITUTE | $42,468,343 | U40 | published | science: research education | Detroit, MI | 2024 |