| ADVANCED TECHNOLOGY INTERNATIONAL | $4,870,021,886 | U99 | published | science: research education | Summerville, SC | 2024 |
| SOUTHWEST RESEARCH INSTITUTE | $978,595,721 | U99 | published | space: outer | San Antonio, TX | 2024 |
| FERMI FORWARD DISCOVERY GROUP LLC | $645,523,193 | U99 | published | science: research education | Batavia, IL | 2024 |
| INTERNET CORPORATION FOR ASSIGNED NAMES AND NUMBERS | $194,948,725 | U99 | published | | Los Angeles, CA | 2024 |
| THE HIGH Q FOUNDATION INC | $152,192,779 | U99 | published | science: research education | Roseland, NJ | 2023 |
| ASSOCIATED UNIVERSITIES INC | $145,098,658 | U99 | published | space: outer | Vienna, VA | 2024 |
| INTER-INDUSTRY CONFERENCE ON AUTO COLLISION REPAIRS | $79,722,947 | U99 | inferred 0.50 | | Hoffman Est, IL | 2025 |
| CONSORTIUM FOR ENERGY ENVIRONMENT AND | $62,964,398 | U99 | inferred 0.70 | science: research education | Washington, DC | 2016 |
| HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY | $52,208,987 | U99 | published | science: research education | Huntsville, AL | 2024 |
| ACORD CORPORATION | $35,623,774 | U99 | inferred 0.80 | | Little Falls, NJ | 2024 |
| AMERICAN ASSOCIATION FOR LABORATORY ACCREDITATION | $28,768,808 | U99 | published | launch: launch | Frederick, MD | 2025 |
| NOBLEREACH FOUNDATION | $27,882,963 | U99 | published | science: research education | Tysons, VA | 2025 |
| FUTURE OF LIFE INSTITUTE | $21,273,381 | U99 | published | science: research education | Narberth, PA | 2024 |
| SAN DIEGO DATA PROCESSING CORP | $19,486,796 | U99 | inferred 0.50 | | San Diego, CA | 2012 |
| NATIONAL ENVIRONMENTAL HEALTH | $18,354,157 | U99 | inferred 0.60 | | Denver, CO | 2024 |
| OPEN RESEARCH LAB INC | $18,298,154 | U99 | published | | San Francisco, CA | 2024 |
| UT-BATTELLE DEVELOPMENT CORPORATION | $15,725,089 | U99 | published | science: research education | Oak Ridge, TN | 2024 |
| NATIONAL COMMISSION FOR THE CERT OF CRANE OPERATORS INC | $15,569,920 | U99 | inferred 0.80 | | Murray, UT | 2025 |
| CENTER FOR TRANSPORTATION AND THE ENVIROMENT INC | $14,957,271 | U99 | published | | Atlanta, GA | 2025 |
| SIERRA INSTITUTE FOR COMMUNITY AND | $13,259,145 | U99 | published | | Taylorsville, CA | 2024 |
| UNIVERSITY OF RHODE ISLAND RESEARCH FOUNDATION | $12,484,796 | U99 | published | science: research education | Kingston, RI | 2024 |
| SIA FOUNDATION INC | $12,298,041 | U99 | published | | Randolph, MA | 2024 |
| WGU LABS | $10,985,368 | U99 | inferred 0.45 | | Salt Lake City, UT | 2022 |
| FOUNDATION FOR ENERGY SECURITY AND INNOVATION INC | $10,629,764 | U99 | published | | Arlington, VA | 2025 |
| SOUTH CAROLINA QUANTUM ASSOCIATION | $10,068,137 | U99 | inferred 0.60 | | Columbia, SC | 2025 |
| NEW PUBLIC | $9,839,509 | U99 | published | | Oakland, CA | 2025 |
| DUCTILE IRON PIPE RESEARCH ASSOCIATION | $9,045,957 | U99 | inferred 0.60 | | Birmingham, AL | 2025 |
| INTERNATIONAL CONFERENCE ON MACHINE LEARNING | $9,028,974 | U99 | published | | San Diego, CA | 2025 |
| ELIFE SCIENCES PUBLICATIONS LTD | $8,521,832 | U99 | published | science: research education | United Kingdom | 2024 |
| INTEROPERABILITY MONTANA | $8,319,687 | U99 | inferred 0.45 | | Helena, MT | 2010 |
| MITRE ENGENUITY INCORPORATED | $8,318,024 | U99 | inferred 0.50 | | Mclean, VA | 2020 |
| WADHWANI INSTITUTE FOR ARTIFICIAL INTELLIGENCE FOUNDATION | $8,270,131 | U99 | published | | Los Altos, CA | 2024 |
| IMEC INC | $7,940,403 | U99 | published | science: research education | San Francisco, CA | 2024 |
| FRIENDS OF THE RUSSELL C DAVIS PLANETARIUM INC | $7,696,102 | U99 | published | space: outer | Jackson, MS | 2024 |
| CENTER FOR GREEN MARKET ACTIVATION | $7,321,130 | U99 | published | | Washington, DC | 2025 |
| STRATEGIC EDUCATION RESEARCH PARTNERSHIP INSTITUTE | $7,093,914 | U99 | published | science: research education | Washington, DC | 2025 |
| APPRAISAL FOUNDATION | $6,834,947 | U99 | inferred 0.80 | launch: launch | Washington, DC | 2024 |
| IDENTITY TECHNOLOGIES INC | $6,647,375 | U99 | inferred 0.40 | | Las Vegas, NV | 2024 |
| MIRROR BIOLOGY DIALOGUES FUND | $6,205,000 | U99 | published | | Dover, DE | 2024 |
| AMERICAN VACUUM SOCIETY INCORPORATED | $6,189,288 | U99 | published | science: research education | New York, NY | 2024 |
| HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE | $5,906,429 | U99 | published | survivor: cancer | Washington, DC | 2024 |
| IMEC USA NANOELECTRONICS DESIGN CENTER | $5,846,432 | U99 | published | science: research education | Kissimmee, FL | 2024 |
| AMERICAN RAILWAY ENGINEERING AND MAINTENANCE OF WAY ASSOCIATION | $5,507,158 | U99 | inferred 0.60 | | Lanham, MD | 2024 |
| ELECTRI INTERNATIONAL THE FOUNDATION FOR ELECTRICAL | $5,454,741 | U99 | published | | Washington, DC | 2024 |
| OPEN MOLECULAR SOFTWARE FOUNDATION | $5,422,298 | U99 | published | launch: launch | Berkeley, CA | 2024 |
| DISTRICT INC | $5,309,567 | U99 | published | | Washington, DC | 2024 |
| RUST FOUNDATION | $5,274,907 | U99 | inferred 0.55 | | Dover, DE | 2025 |
| SCINTILLON INSTITUTE | $5,125,626 | U99 | published | science: research education | San Diego, CA | 2024 |
| FRAGRANCE FOUNDATION INC | $4,972,389 | U99 | published | | New York, NY | 2025 |
| SIGMA XI THE SCIENTIFIC RESEARCH HONOR SOCIETY INC | $4,861,984 | U99 | inferred 0.80 | science: research education | Durham, NC | 2024 |
| FRACTIONATION RESEARCH INC | $4,701,817 | U99 | inferred 0.80 | science: research education | Stillwater, OK | 2024 |
| STUDENTS 2 SCIENCE | $4,541,920 | U99 | published | science: research education | Whippany, NJ | 2024 |
| SURFACE MOUNT TECHNOLOGY ASSOCIATION INC | $4,315,571 | U99 | inferred 0.60 | | Eden Prairie, MN | 2025 |
| WILLIAM & MARY GREVE FOUNDATION INC | $4,205,559 | U99 | published | violence: prevention | Norfolk, CT | 2024 |
| KENTUCKY DATASEAM INITIATIVE INC | $4,186,341 | U99 | published | space: outer | Louisville, KY | 2024 |
| BOARD OF CERTIFICATION ACCREDITATION INTERNATIONAL | $4,087,477 | U99 | inferred 0.45 | | Owings Mills, MD | 2025 |
| KESTREL INSTITUTE | $3,874,883 | U99 | inferred 0.80 | space: outer | Palo Alto, CA | 2024 |
| ZCASH FOUNDATION | $3,769,087 | U99 | published | science: research education | Mclean, VA | 2024 |
| AMERICAN MEAT SCIENCE ASSOCIATION | $3,505,196 | U99 | published | science: research education | Kearney, MO | 2024 |
| SOCIETY OF TRIBOLOGISTS & LUBRICATION ENGINEERS | $3,391,609 | U99 | published | science: research education | Park Ridge, IL | 2024 |
| TELLURIDE SCIENCE | $3,150,657 | U99 | inferred 0.75 | science: research education | Telluride, CO | 2024 |
| THE WELLMARK FOUNDATION | $3,039,209 | U99 | inferred 0.50 | girls boys: boys | Des Moines, IA | 2024 |
| POLICY RESEARCH INC | $2,921,311 | U99 | published | abuse: substance | Troy, NY | 2024 |
| INWATER GROUP RESEARCH INC | $2,750,460 | U99 | published | science: research education | Jensen Beach, FL | 2025 |
| WEST VIRGINIA UNIVERSITY INNOVATION CORPORATION | $2,710,934 | U99 | published | science: research education | Morgantown, WV | 2024 |
| FIRA CONSORTIUM INC | $2,651,812 | U99 | inferred 0.45 | | Beaverton, OR | 2024 |
| MOLECULAR SCIENCES RESEARCH CENTER INC | $2,534,045 | U99 | published | science: research education | San Juan, PR | 2024 |
| BIONANOMICS INC | $2,528,927 | U99 | published | science: research education | Fort Wayne, IN | 2024 |
| QUALITY EXCELLENCE FOR SUPPLIERS OF | $2,520,776 | U99 | inferred 0.50 | | Plano, TX | 2016 |
| RESEARCH INSTITUTE FOR LEARNING AND DEVELOPMENT | $2,474,427 | U99 | published | | Lexington, MA | 2024 |
| OPENDAYLIGHT PROJECT INC | $2,455,873 | U99 | inferred 0.80 | | San Francisco, CA | 2017 |
| IOWA CROP IMPPROVEMENT ASSOCIATION | $2,444,692 | U99 | inferred 0.80 | | Ames, IA | 2025 |
| ADVENTURELAND INSTITUTE INC | $2,433,024 | U99 | published | science: research education | St Petersburg, FL | 2024 |
| CHINA CLASSIFICATION SOCIETY | $2,321,154 | U99 | inferred 0.45 | | Great Neck, NY | 2024 |
| MARAGIN HEALTH FOUNDATION | $2,304,977 | U99 | published | science: research education | Irving, TX | 2023 |
| GLOBAL COLD CHAIN FOUNDATION | $2,255,015 | U99 | published | | Arlington, VA | 2024 |
| PHOENIX BIOINFORMATICS CORPORATION | $2,237,798 | U99 | published | science: research education | Newark, CA | 2025 |
| ROBOT LEARNING FOUNDATION INC | $2,232,211 | U99 | published | | Cupertino, CA | 2025 |
| INTERNATIONAL INTERNET TESTING | $2,193,037 | U99 | inferred 0.45 | | Downers Grove, IL | 2022 |
| INTERNATIONAL MICROELECTRONICS AND PACKAGING SOCIETY | $2,106,642 | U99 | inferred 0.80 | science: research education | Pittsburgh, PA | 2024 |
| ISEV INC | $2,000,245 | U99 | published | science: research education | Mount Royal, NJ | 2024 |
| UNITED STATES ADVANCED TELEVISION SYSTEMS COMMITTEE | $1,967,751 | U99 | inferred 0.50 | | Washington, DC | 2025 |
| CERTIFICATION BOARD OF INFECTION CONTROL | $1,957,765 | U99 | inferred 0.50 | | Arlington, VA | 2024 |
| UNITED SACRAMENT MOBILE INT INC | $1,900,000 | U99 | published | | Miami, FL | 2024 |
| INTERNATIONAL ARCHAEOLOGICAL RESEARCH INSTITUTE INC | $1,877,527 | U99 | inferred 0.70 | science: research education | Honolulu, HI | 2024 |
| THE MAINE NARROW GAUGE RAILROAD AND INDUSTRIAL HERTIAGE TRUST | $1,839,157 | U99 | published | | Portland, ME | 2023 |
| EDGE INSTITUTE INC | $1,801,537 | U99 | published | | Austin, TX | 2024 |
| FOX-WOLF WATERSHED ALLIANCE INC | $1,778,343 | U99 | published | science: research education | Appleton, WI | 2025 |
| OSTEOARTHRITIS RESEARCH SOCIETY INTERNATIONAL INC | $1,767,697 | U99 | published | | Mount Laurel, NJ | 2025 |
| US FASTER PAYMENTS COUNCIL INC | $1,764,577 | U99 | published | | Bentonville, AR | 2025 |
| RESPONSIBLE ARTIFICIAL INTELLIGENCE INSTITUTE | $1,743,850 | U99 | published | | Austin, TX | 2023 |
| STATE SCIENCE AND TECHNOLOGY INSTITUTE | $1,705,018 | U99 | published | science: research education | Columbus, OH | 2024 |
| INTERNATIONAL BOARD OF HEART RHYTHM EXAMINERS INC | $1,693,147 | U99 | inferred 0.60 | | Washington, DC | 2024 |
| GIVEDIGNIFIEDWORK INC | $1,681,951 | U99 | published | | Bothell, WA | 2024 |
| BOARD FOR GLOBAL EHS CREDENTIALING | $1,679,410 | U99 | inferred 0.60 | | Mclean, VA | 2024 |
| IOWA ASSOCIATION OF SOIL CONSERVATION DISTRICT COMMISSION | $1,634,841 | U99 | published | | Des Moines, IA | 2024 |
| THE ABLEGAMERS FOUNDATION INC | $1,627,000 | U99 | published | | Charles Town, WV | 2024 |
| TATTA BIO | $1,616,667 | U99 | published | | Cambridge, MA | 2024 |
| DYNAMICLAND FOUNDATION | $1,593,303 | U99 | published | science: research education | Berkeley, CA | 2025 |
| INTERNATIONAL NEURAL NETWORK SOCIETY | $1,533,342 | U99 | inferred 0.60 | science: research education | Gainesville, FL | 2025 |