| INTERNATIONAL INFORMATION SYSTEM SECURITY CERTIFICATION CONSORTIUM | $87,659,863 | U41 | inferred 0.45 | | Alexandria, VA | 2025 |
| UNIVERSITY CORPORATION FOR ADVANCED INTERNET DEVELOPMENT | $81,580,045 | U41 | published | science: research education | Ann Arbor, MI | 2024 |
| ASTERA INSTITUTE | $72,283,069 | U41 | published | science: research education | Berkeley, CA | 2024 |
| WATERFORD INSTITUTE INC | $48,299,857 | U41 | published | science: research education | Taylorsville, UT | 2024 |
| VIRGINIA INNOVATION PARTNERSHIP CORPORATION | $33,814,047 | U41 | published | space: outer | Herndon, VA | 2024 |
| FLORIDA INSTITUTE FOR HUMAN AND MACHINE COGNITION | $33,179,379 | U41 | published | science: research education | Pensacola, FL | 2024 |
| GRIFFISS INSTITUTE INC | $26,582,580 | U41 | published | science: research education | Rome, NY | 2025 |
| HACK FOUNDATION | $22,351,707 | U41 | published | science: research education | W Hollywood, CA | 2024 |
| SCRATCH FOUNDATION | $20,013,298 | U41 | published | violence: community | New York, NY | 2024 |
| STACKS OPEN INTERNET FOUNDATION | $12,033,900 | U41 | inferred 0.50 | | Cary, NC | 2023 |
| NATIONAL CYBER FORENSICS AND TRAINING ALLIANCE | $11,281,815 | U41 | published | | Pittsburgh, PA | 2025 |
| WISCNET | $10,562,254 | U41 | published | science: research education | Madison, WI | 2024 |
| CODE FOR SCIENCE AND SOCIETY INC | $10,336,769 | U41 | published | science: research education | Portland, OR | 2024 |
| EMPIRE AI CONSORTIUM | $10,000,000 | U41 | published | | New York, NY | 2024 |
| BANYAN SOFTWARE FOUNDATION INC | $10,000,000 | U41 | published | | Atlanta, GA | 2024 |
| PARTNERSHIP ON AI TO BENEFIT PEOPLE AND SOCIETY | $9,023,889 | U41 | published | science: research education | San Francisco, CA | 2024 |
| KANREN INC | $6,677,948 | U41 | published | | Lawrence, KS | 2024 |
| MEEDAN INC | $6,301,624 | U41 | published | violence: sexual | San Francisco, CA | 2025 |
| OPENMINED FOUNDATION | $6,099,358 | U41 | published | | New York, NY | 2024 |
| POWERMYLEARNING INC | $5,876,922 | U41 | published | | New York, NY | 2024 |
| CONNECTED GIVING FOUNDATION | $5,637,277 | U41 | published | | Fredericksburg, VA | 2024 |
| SEISMIC CATALYST FOUNDATION | $5,248,744 | U41 | published | | Wilmington, DE | 2025 |
| INSTITUTE OF INDUSTRIAL AND SYSTEMS ENGINEERS INC | $5,137,343 | U41 | inferred 0.50 | science: research education | Cumming, GA | 2024 |
| ASSOCIATION FOR THE ADVANCEMENT OF ARTIFICIAL INTELLIGENCE | $5,074,737 | U41 | published | | Washington, DC | 2024 |
| OWASP FOUNDATION INC | $4,340,593 | U41 | published | | Wilmington, DE | 2024 |
| NC IDEA | $4,087,431 | U41 | published | | Durham, NC | 2024 |
| PYTHON SOFTWARE FOUNDATION | $4,086,997 | U41 | published | science: research education | Beaverton, OR | 2024 |
| ORGANIZATION FOR EDUCATIONAL TECHNOLOGY AND CURRICULUM | $3,759,949 | U41 | published | | Lake Oswego, OR | 2024 |
| REAL ESTATE STANDARDS ORGANIZATION | $3,271,731 | U41 | published | | Raleigh, NC | 2025 |
| SOFTWARE FREEDOM CONSERVANCY INC | $3,214,723 | U41 | published | science: research education | Brooklyn, NY | 2024 |
| NEW YORK CITY FOUNDATION FOR COMPUTER SCIENCE EDUCATION | $3,113,266 | U41 | published | science: research education | Katonah, NY | 2024 |
| CORPORATION FOR NATIONAL RESEARCH INITIATIVES | $3,094,378 | U41 | published | science: research education | Reston, VA | 2024 |
| EQUINOX SOFTWARE INC | $3,046,987 | U41 | inferred 0.50 | | Lawrenceville, GA | 2024 |
| THE HDF GROUP | $3,045,316 | U41 | published | space: outer | Champaign, IL | 2025 |
| EAST ASIAN OBSERVATORY | $3,014,426 | U41 | published | space: outer | Hilo, HI | 2024 |
| FREE CODE CAMP INC | $2,986,509 | U41 | published | | Plano, TX | 2024 |
| LUMITY | $2,922,516 | U41 | published | science: research education | Chicago, IL | 2024 |
| ELEUTHERAI INSTITUTE | $2,808,142 | U41 | published | | Washington, DC | 2024 |
| OPEN SOURCE TECHNOLOGY IMPROVEMENT FUND INC | $2,725,898 | U41 | published | science: research education | Chicago, IL | 2025 |
| COMPUTER USING EDUCATORS INC | $2,329,267 | U41 | published | | San Francisco, CA | 2024 |
| APACHE SOFTWARE FOUNDATION | $2,220,257 | U41 | published | | Wilmington, DE | 2024 |
| RASPBERRY PI FOUNDATION NORTH AMERICA INC | $2,161,949 | U41 | published | science: research education | San Francisco, CA | 2025 |
| STANDARD CPP FOUNDATION | $2,102,990 | U41 | published | | Spokane, WA | 2024 |
| OPEN INFORMATION SECURITY FOUNDATION INC | $2,060,506 | U41 | published | | Lafayette, IN | 2025 |
| AI OBJECTIVES INSTITUTE | $1,829,928 | U41 | published | | Wilmington, DE | 2024 |
| THE FREEBSD FOUNDATION | $1,739,644 | U41 | published | | Boulder, CO | 2024 |
| ELECTRONIC DISCOVERY INSTITUTE | $1,633,131 | U41 | published | | Ft Lauderdale, FL | 2024 |
| MARIADB FOUNDATION | $1,609,317 | U41 | inferred 0.60 | | Wakefield, MA | 2024 |
| MACHINE INTELLIGENCE RESEARCH INSTITUTE INC | $1,534,913 | U41 | published | launch: launch | Berkeley, CA | 2024 |
| UNITY FOUNDATION NP | $1,531,769 | U41 | published | | St Louis, MO | 2024 |
| GEEKS WITHOUT FRONTIERS | $1,525,612 | U41 | published | women: issues | Austin, TX | 2024 |
| COMMONCRAWL FOUNDATION | $1,467,641 | U41 | published | | Beverly Hills, CA | 2024 |
| NATIONAL INFORMATION STANDARDS ORGANIZATION Z39 | $1,462,968 | U41 | published | science: research education | Baltimore, MD | 2023 |
| ACCELLERA ORGANIZATION | $1,429,108 | U41 | published | | Elk Grove, CA | 2024 |
| ENTROPY SOFTWARE FOUNDATION INC | $1,350,000 | U41 | published | | Woodbury, NY | 2024 |
| VERY LARGE DATA BASES | $1,344,626 | U41 | inferred 0.50 | | Stanford, CA | 2024 |
| RISEUP LABS | $1,342,644 | U41 | published | | Lacey, WA | 2024 |
| ZERODIVIDE | $1,305,662 | U41 | inferred 0.60 | women: issues | San Francisco, CA | 2014 |
| PACKET CLEARING HOUSE INC | $1,175,101 | U41 | published | | San Francisco, CA | 2025 |
| CERTIFICATION COMMISSION FORHEALTHCARE INFORMATION TECHNOLOGY | $1,127,428 | U41 | published | launch: launch | Chicago, IL | 2014 |
| OPEN SOURCE INITIATIVE | $1,093,077 | U41 | published | | W Hollywood, CA | 2024 |
| POST ROAD FOUNDATION | $1,083,755 | U41 | published | | Oakland, CA | 2024 |
| BLACK FARMERS COLLECTIVE | $1,065,821 | U41 | published | | Seattle, WA | 2025 |
| DATA TRANSFER PROJECT INC | $1,059,691 | U41 | published | | Tacoma, WA | 2025 |
| FEDORA COMMONS INC | $1,039,056 | U41 | inferred 0.60 | | Atlanta, GA | 2019 |
| EDBUILD INC | $1,023,750 | U41 | published | | Jersey City, NJ | 2024 |
| BEAGLEBOARD ORG FOUNDATION | $1,019,112 | U41 | published | | Oakland Twp, MI | 2024 |
| OPEN SOURCE PROJECT FOR A NETWORK | $985,957 | U41 | published | space: outer | Saunderstown, RI | 2024 |
| DALLAS MAKERSPACE | $963,294 | U41 | published | science: research education | Carrollton, TX | 2024 |
| AI FOR GOOD FOUNDATION | $954,854 | U41 | published | shelter: disaster | El Cerrito, CA | 2024 |
| DIGITRUST INC | $927,500 | U41 | inferred 0.45 | | Bellingham, WA | 2017 |
| ZIG SOFTWARE FOUNDATION INC | $921,832 | U41 | published | | New York, NY | 2025 |
| NEW MEXICO COMPUTING APPLICATIONS CENTER INC | $919,374 | U41 | inferred 0.50 | science: research education | Albuquerque, NM | 2010 |
| LMSYS CORP | $889,293 | U41 | published | | Sacramento, CA | 2025 |
| NETWORK FOR OPEN SCIENTIFICINNOVATION | $871,063 | U41 | published | science: research education | Carlsbad, CA | 2025 |
| UNICODE INC | $860,373 | U41 | published | | S San Fran, CA | 2025 |
| OPEN LIBRARY FOUNDATION | $843,542 | U41 | published | | Philadelphia, PA | 2024 |
| MID-ATLANTIC RESEARCH INFRASTRUCTURE ALLIANCE | $820,106 | U41 | published | | Blacksburg, VA | 2024 |
| MISSISSIPPI CODING ACADEMIES | $736,638 | U41 | published | | Jackson, MS | 2024 |
| SOFTWARE IN THE PUBLIC INTEREST INC | $685,055 | U41 | published | women: issues | New York, NY | 2024 |
| PISCES INTERNATIONAL | $609,216 | U41 | published | | Bremerton, WA | 2025 |
| ECLIPSEORG FOUNDATION INC | $549,568 | U41 | inferred 0.60 | | Portland, OR | 2024 |
| WISCONSIN LIVESTOCK IDENTIFICATION CONSORTIUM INC | $512,982 | U41 | published | | Madison, WI | 2025 |
| INFORMATION SYSTEMS SECURITY ASSOCIATION | $504,655 | U41 | inferred 0.50 | science: research education | Durham, NC | 2024 |
| AGILE EVENTS | $477,325 | U41 | published | | Saline, MI | 2023 |
| PROJECT-HAYSTACK | $459,504 | U41 | published | | Glen Allen, VA | 2025 |
| WINTRISS TECHNICAL SCHOOLS INC | $453,227 | U41 | published | women: issues | San Diego, CA | 2025 |
| IIW FOUNDATION | $434,763 | U41 | published | | Lindon, UT | 2025 |
| ANGAZA TECHNOLOGY LITERACY CENTER NFP | $427,817 | U41 | published | | Washington, DC | 2025 |
| COALITION FOR ACADEMIC SCIENTIFIC COMPUTATION INC | $424,207 | U41 | published | science: research education | Washington, DC | 2024 |
| DEFI FIRST IMPROVING CODE SECURITY | $407,953 | U41 | published | | Seattle, WA | 2024 |
| METAGOV INC | $391,471 | U41 | published | science: research education | Boston, MA | 2023 |
| BLACK COLLEGIATE GAMING ASSOCIATION FOUNDATION INC | $366,500 | U41 | published | | Atlanta, GA | 2025 |
| HUBZONE TECHNOLOGY INITIATIVE INC | $363,940 | U41 | published | science: research education | Henderson, NC | 2025 |
| SIMULATION COUNCILS INC | $357,894 | U41 | published | | San Diego, CA | 2024 |
| NETWORK TIME FOUNDATION INC | $339,941 | U41 | published | | Talent, OR | 2025 |
| TECHNOCATION | $325,983 | U41 | published | | Plympton, MA | 2018 |
| SOFTWARE EDUCATION FOUNDATION | $295,283 | U41 | published | science: research education | Washington, DC | 2024 |
| SOCIAL IMPACT LAB FOUNDATION | $294,858 | U41 | inferred 0.45 | | Washington, DC | 2015 |
| APS TRAINING INSTITUTE INC | $287,041 | U41 | published | girls boys: boys girls clubs | Aurora, IL | 2024 |