| PEOPLE FOR THE ETHICAL TREATMENT OF ANIMALS INC | $110,179,122 | D01 | published | domestic: animals | Norfolk, VA | 2024 |
| KARUNA FOUNDATION | $34,225,206 | D01 | published | | Cheyenne, WY | 2025 |
| AMERICAN BIRD CONSERVANCY | $26,955,379 | D01 | published | science: research education | Marshall, VA | 2024 |
| SAFARI CLUB INTERNATIONAL | $23,134,364 | D01 | published | | San Antonio, TX | 2024 |
| ANIMAL LEGAL DEFENSE FUND | $19,716,926 | D01 | published | abuse: animal | Sacramento, CA | 2024 |
| SEA SHEPHERD CONSERVATION SOCIETY | $15,110,537 | D01 | published | shelter: animal | Woodbridge, VA | 2024 |
| BORN FREE USA UNITED WITH ANIMAL PROTECTION INSTITUTE | $8,346,516 | D01 | published | abuse: animal | Silver Spring, MD | 2025 |
| DOLPHIN RESEARCH CENTER INC | $7,578,339 | D01 | published | | Grassy Key, FL | 2024 |
| CHEETAH CONSERVATION FUND | $6,714,660 | D01 | published | science: research education | Alexandria, VA | 2024 |
| CALIFORNIA AIR POLLUTION CONTROL OFFICERS ASSOCIATION | $6,575,229 | D01 | inferred 0.60 | | Sacramento, CA | 2024 |
| HUMANE WORLD ACTIN FUND | $6,371,045 | D01 | published | shelter: animal | Washington, DC | 2025 |
| NATIONAL ANTI-VIVISECTION SOCIETY | $4,619,734 | D01 | published | abuse: animal | Chicago, IL | 2024 |
| AMERICAN ANTI-VIVISECTION SOCIETY | $4,097,874 | D01 | published | science: research education | Jenkintown, PA | 2025 |
| WILDLIFE ASSOCIATION OF TEXAS | $3,751,527 | D01 | published | | New Braunfels, TX | 2024 |
| SAVE THE MANATEE CLUB INC | $3,622,211 | D01 | published | science: research education | Longwood, FL | 2024 |
| UNITED STATES SPORTSMENS ALLIANCE FOUNDATION | $3,086,890 | D01 | published | science: research education | Columbus, OH | 2024 |
| IN DEFENSE OF ANIMALS | $2,883,891 | D01 | published | abuse: animal | San Rafael, CA | 2024 |
| ANIMAL RESCUE COALITION INC | $2,802,259 | D01 | published | shelter: animal | Sarasota, FL | 2024 |
| LAST CHANCE FOR ANIMALS | $2,613,718 | D01 | published | launch: aviation | Los Angeles, CA | 2024 |
| WILDLIFE REHABILITATION CENTER | $2,609,844 | D01 | published | | Roseville, MN | 2024 |
| ANIMAL OUTLOOK INC | $2,261,995 | D01 | published | abuse: animal | Takoma Park, MD | 2025 |
| TEXAS CONSERVATION ALLIANCE | $2,112,197 | D01 | published | science: research education | Dallas, TX | 2024 |
| SECOND CHANCES FOR BLIND DOGS FOUNDATION INC | $2,064,362 | D01 | published | launch: religious | Sherman Oaks, CA | 2024 |
| CONSERVATION FORCE INC | $2,028,055 | D01 | published | | Metairie, LA | 2024 |
| LEGAL IMPACT FOR CHICKENS | $1,917,001 | D01 | published | | Sacramento, CA | 2024 |
| GEORGIA WILDLIFE FEDERATION | $1,909,448 | D01 | published | | Covington, GA | 2024 |
| BRISTOL BAY REGIONAL SEAFOOD DEVELOPMENT ASSOCIATION | $1,896,792 | D01 | published | science: research education | Anchorage, AK | 2024 |
| FLORIDA WILDLIFE FEDERATION | $1,655,243 | D01 | published | science: research education | Tallahassee, FL | 2024 |
| EAGLEWATCH INC | $1,606,069 | D01 | published | science: research education | Wabasha, MN | 2024 |
| LOUISIANA WILDLIFE FEDERATION INC | $1,596,958 | D01 | published | | Baton Rouge, LA | 2024 |
| INTERNATIONAL COUNCIL FOR ANIMAL WELFARE INC | $1,587,395 | D01 | published | | Philadelphia, PA | 2025 |
| RICHMOND ANIMAL WELFARE FOUNDATION | $1,459,279 | D01 | published | shelter: animal | Richmond, VA | 2025 |
| SPAY AND NEUTER INITIATIVE PROGRAM | $1,443,332 | D01 | published | | Alvin, TX | 2025 |
| ALTERNATIVES FOR RESEARCH AND DEVELOPMENT FOUNDATION | $1,391,661 | D01 | published | science: research education | Jenkintown, PA | 2025 |
| GARDNER CRENSHAW FOUNDATION | $1,313,774 | D01 | published | abuse: animal | Campbellsvlle, KY | 2024 |
| FARM FORWARD INC | $1,226,680 | D01 | published | | Portland, OR | 2024 |
| ROCKING R RANCH & RESCUE INC | $1,216,110 | D01 | published | abuse: animal | Kosciusko, MS | 2024 |
| NATIONAL WILDLIFE REFUGE ASSOCIATION | $1,193,106 | D01 | published | science: research education | Washington, DC | 2024 |
| ENDANGERED HABITATS LEAGUE INC | $1,103,617 | D01 | published | science: research education | Los Angeles, CA | 2025 |
| TEXAS HUMANE LEGISLATION NETWORK INC | $1,016,627 | D01 | published | abuse: animal | Dallas, TX | 2025 |
| HUMANE SOCIETY OF MASON COUNTY | $1,006,885 | D01 | published | shelter: animal | Belfair, WA | 2024 |
| WASHINGTON WILD | $966,572 | D01 | published | launch: launch | Seattle, WA | 2024 |
| ROCKY MOUNTAIN WOLF ACTION FUND | $956,141 | D01 | inferred 0.60 | | Lafeyette, CO | 2020 |
| ILLINOIS STATE VETERINARY MEDICAL ASSOCIATION | $942,870 | D01 | inferred 0.60 | | Springfield, IL | 2024 |
| FOOD ANIMAL CONCERNS TRUST | $901,531 | D01 | published | | Washington, DC | 2024 |
| ONE TAIL AT A TIME WEST TEXAS | $811,635 | D01 | published | shelter: animal | Terlingua, TX | 2025 |
| WYOMING WILDLIFE FEDERATION | $805,051 | D01 | published | | Lander, WY | 2024 |
| SOUTH TEXAS ANIMAL RESCUE GROUP | $781,451 | D01 | published | | Corp Christi, TX | 2024 |
| CENTER FOR RESPONSIBLE COMMERCE | $773,712 | D01 | published | | Bethlehem, PA | 2024 |
| UNITED STATES WAR DOGS ASSOCIATION INC | $753,531 | D01 | published | | Towson, MD | 2024 |
| SAVE OUR WILD SALMON COALITION | $753,472 | D01 | published | | Seattle, WA | 2024 |
| A PATH 4 PAWS DOG RESCUE | $752,933 | D01 | published | | Amargosa Vly, NV | 2025 |
| ANIMAL SURVIVAL INTERNATIONAL USA INC | $749,153 | D01 | published | abuse: animal | Sanibel, FL | 2025 |
| GREY2K USA WORLDWIDE INC | $738,672 | D01 | published | | Arlington, MA | 2024 |
| MOUNTAIN LION FOUNDATION | $725,489 | D01 | published | science: research education | Sacramento, CA | 2024 |
| KITTY KAT HAVEN & RESCUE | $714,298 | D01 | published | shelter: animal | Hoover, AL | 2024 |
| MOON MOUNTAIN SANCTUARY AND RESCUE | $693,012 | D01 | published | shelter: animal | Mena, AR | 2024 |
| MONTANA WILDLIFE FEDERATION | $675,423 | D01 | published | | Missoula, MT | 2024 |
| ANIMAL RIGHTS FOUNDATION OF FLORIDA INC | $635,215 | D01 | published | abuse: animal | Ft Lauderdale, FL | 2025 |
| FOLLOW YOUR HEART FOUNDATION INC | $625,323 | D01 | published | shelter: animal | Mesa, AZ | 2025 |
| SOUTH CAROLINA WILDLIFE FEDERATION | $619,465 | D01 | published | | Columbia, SC | 2025 |
| MISSOURI ANGUS ASSOCIATION | $615,539 | D01 | inferred 0.60 | | Holden, MO | 2025 |
| OINKING ACRES FARM RESCUE & SANCTUARY INC | $605,074 | D01 | published | abuse: animal | Brownsburg, IN | 2024 |
| PAWSWITHCAUSE | $579,989 | D01 | published | shelter: animal | Lake Stevens, WA | 2025 |
| A HOPE INC | $576,090 | D01 | published | shelter: animal | Milton, FL | 2025 |
| PHX CAT CAFE | $572,778 | D01 | published | | Phoenix, AZ | 2025 |
| GAL S BEST PAL INCORPORATED | $569,801 | D01 | published | abuse: animal | Saugus, MA | 2024 |
| COMPANION ANIMAL MEDICAL PROJECT | $566,469 | D01 | published | shelter: animal | Bend, OR | 2025 |
| FARM ANIMAL REFORM MOVEMENT INC | $549,800 | D01 | published | | Ithaca, NY | 2024 |
| SOCIAL COMPASSION IN LEGISLATION | $533,297 | D01 | published | | Laguna Beach, CA | 2025 |
| ANIMAL PROTECTION AGENCY | $517,985 | D01 | published | | Santa Clarita, CA | 2025 |
| SAFE PET PROJECT INC | $513,389 | D01 | published | | Blairsville, GA | 2024 |
| VEGAN FRIENDLY | $505,071 | D01 | published | | Santa Monica, CA | 2024 |
| WILDLIFE ACTION INC | $504,834 | D01 | published | | Mullins, SC | 2024 |
| ANIMAL PROTECTION VOTERS | $494,132 | D01 | inferred 0.70 | abuse: sexual | Albuquerque, NM | 2024 |
| DIRECT ACTION EVERYWHERE | $493,717 | D01 | published | | Berkeley, CA | 2024 |
| WYOMING WILDLIFE ADVOCATES | $493,587 | D01 | published | | Wilson, WY | 2024 |
| MISSOURI ALLIANCE FOR ANIMAL LEGISLATION | $479,237 | D01 | inferred 0.90 | | Saint Louis, MO | 2024 |
| ANIMALKIND INC | $477,484 | D01 | published | | Raleigh, NC | 2024 |
| PAWSITIVE TAILS INC | $477,026 | D01 | published | | Olathe, KS | 2024 |
| PRO-ANIMAL FUTURE | $468,366 | D01 | published | | Boulder, CO | 2024 |
| SAVED BY ZADE | $462,079 | D01 | published | shelter: animal | Eaton Rapids, MI | 2025 |
| COMPASSIONATE ACTION FOR ANIMALS | $461,060 | D01 | published | | Minneapolis, MN | 2024 |
| SHELTER A MUTT INC | $451,805 | D01 | published | abuse: animal | Corp Christi, TX | 2025 |
| CITIZENS FOR LOS ANGELES WILDLIFE INC | $443,485 | D01 | published | | Studio City, CA | 2024 |
| WASHINGTON WILDLIFE FIRST | $422,181 | D01 | inferred 0.80 | | Copalis Xing, WA | 2024 |
| OPEN SANCTUARY PROJECT INC | $418,592 | D01 | published | | Niwot, CO | 2024 |
| A TIME 4 PAWS | $413,207 | D01 | published | abuse: animal | Crossville, TN | 2025 |
| INTERNATIONAL FOUNDATION FOR ETHICAL RESEARCH INC | $409,060 | D01 | published | science: research education | Chicago, IL | 2025 |
| CELESTIAL ZOO PET RESCUE | $405,544 | D01 | published | | Eagle Mtn, UT | 2025 |
| ANIMAL ALLIANCE ASIA | $390,399 | D01 | published | | Smyrna, DE | 2025 |
| ANGEL PAWS | $386,459 | D01 | published | | Murray, UT | 2024 |
| STOP ANIMAL EXPLOITATION NOW | $381,227 | D01 | published | abuse: animal | Milford, OH | 2024 |
| SOUTHERN STATES BULLY RESCUE INC | $377,901 | D01 | published | abuse: animal | Ormond Beach, FL | 2024 |
| UNITED SPAY ALLIANCE | $376,244 | D01 | published | | Walkersville, MD | 2025 |
| BIG HOOF FOUNDATION | $375,969 | D01 | published | abuse: animal | Amarillo, TX | 2024 |
| ANIMAL WELFARE ALLIANCE RESOURCE & EDUCATION OF NH | $370,372 | D01 | published | | Manchester, NH | 2025 |
| NO KILL GLYNN COUNTY INC | $369,977 | D01 | published | shelter: animal | St Simons Is, GA | 2025 |
| THE AMERICAN BEAR ASSOCIATION | $369,624 | D01 | published | | Orr, MN | 2024 |
| MISSISSIPPI WILDLIFE FEDERATION | $365,303 | D01 | published | | Jackson, MS | 2024 |