| GAVI ALLIANCE | $2,547,417,284 | Q33 | published | women: issues | Washington, DC | 2024 |
| DIRECT RELIEF | $2,398,998,642 | Q33 | published | abuse: substance | Santa Barbara, CA | 2024 |
| INTERNATIONAL COMMITTEE OF THE RED CROSS | $2,299,493,810 | Q33 | published | | Switzerland | 2024 |
| WORLD VISION | $1,423,305,144 | Q33 | published | girls boys: boys girls clubs | Federal Way, WA | 2024 |
| MAP INTERNATIONAL | $1,379,040,410 | Q33 | published | violence: sexual | Brunswick, GA | 2024 |
| COMPASSION INTERNATIONAL INCORPORATED | $953,223,395 | Q33 | published | women: issues | Colorado Spgs, CO | 2018 |
| SAVE THE CHILDREN FEDERATION INC | $920,455,828 | Q33 | published | domestic: workers | Fairfield, CT | 2024 |
| PLAN INTERNATIONAL INC | $779,465,250 | Q33 | published | shelter: disaster | New York, NY | 2024 |
| CONVOY OF HOPE | $435,592,269 | Q33 | published | survivor: disaster | Springfield, MO | 2021 |
| AMERICAN JEWISH JOINT DISTRIBUTION COMMITTEE INC | $412,907,647 | Q33 | published | survivor: disaster | New York, NY | 2024 |
| FOOD FOR THE POOR INC | $412,105,034 | Q33 | published | violence: community | Coconut Creek, FL | 2024 |
| FEED THE CHILDREN INC | $386,446,959 | Q33 | published | shelter: disaster | Oklahoma City, OK | 2024 |
| MERCY CORPS | $376,251,780 | Q33 | published | space: for women | Portland, OR | 2024 |
| HABITAT FOR HUMANITY INTERNATIONAL INC | $370,010,910 | Q33 | published | launch: launch | Atlanta, GA | 2024 |
| HEART TO HEART INTERNATIONAL INC | $347,317,501 | Q33 | published | | Lenexa, KS | 2025 |
| WORLD CENTRAL KITCHEN INCORPORATED | $327,840,221 | Q33 | published | women: issues | Washington, DC | 2024 |
| INTERNATIONAL FELLOWSHIP OF CHRISTIANS & JEWS | $318,221,645 | Q33 | inferred 0.60 | launch: aviation | Chicago, IL | 2024 |
| AAM FOUNDATION | $300,813,850 | Q33 | published | shelter: homeless | Novato, CA | 2024 |
| CHURCH WORLD SERVICE INC | $279,865,803 | Q33 | published | survivor: disaster | Elkhart, IN | 2024 |
| MERCY SHIPS INTERNATIONAL | $250,375,032 | Q33 | published | | Lindale, TX | 2025 |
| CLINTON HEALTH ACCESS INITIATIVE INC | $246,122,771 | Q33 | published | launch: launch | Boston, MA | 2024 |
| INTERNATIONAL MEDICAL CORPS | $235,323,065 | Q33 | published | shelter: disaster | Los Angeles, CA | 2024 |
| CHILDRENS HUNGER FUND | $215,110,859 | Q33 | published | | Rnch Cascades, CA | 2025 |
| CHILDFUND INTERNATIONAL USA | $210,435,038 | Q33 | published | | Richmond, VA | 2024 |
| WORLD RELIEF CORPORATION O NATIONAL | $205,941,236 | Q33 | published | shelter: disaster | Baltimore, MD | 2024 |
| ACADEMY FOR EDUCATIONAL DEVELOPMENT | $202,437,786 | Q33 | inferred 0.50 | | Washington, DC | 2011 |
| HEIFER PROJECT INTERNATIONAL | $162,027,025 | Q33 | published | women: issues | Little Rock, AR | 2024 |
| RISE AGAINST HUNGER | $155,585,447 | Q33 | published | violence: community | Raleigh, NC | 2025 |
| MANA NUTRITIVE AID PRODUCTS INC | $138,046,810 | Q33 | published | | Matthews, NC | 2024 |
| UNITED PALESTINIAN APPEAL INC | $120,665,815 | Q33 | published | | Washington, DC | 2024 |
| HALO TRUST USA INC | $97,207,878 | Q33 | published | violence: gun | Washington, DC | 2024 |
| OPERATION BLESSING INTERNATIONAL RELIEF & DEVELOPMENT CORP | $78,244,217 | Q33 | published | launch: religious | Virginia Bch, VA | 2024 |
| FEED MY STARVING CHILDREN | $77,545,563 | Q33 | published | | Coon Rapids, MN | 2025 |
| BAITULMAAL INC | $76,144,403 | Q33 | published | women: issues | Irving, TX | 2024 |
| GOOD NEIGHBORS GLOBAL PARTNERSHIP CENTER | $72,097,240 | Q33 | published | | Tustin, CA | 2025 |
| LUTHERAN WORLD RELIEF INC | $71,718,541 | Q33 | published | women: issues | Baltimore, MD | 2024 |
| RELIEF INTERNATIONAL INC | $66,127,909 | Q33 | published | shelter: disaster | Washington, DC | 2024 |
| SALVADORAN AMERICAN HUMANITARIAN FOUNDATION INC | $65,520,408 | Q33 | published | | Coral Gables, FL | 2025 |
| CGIAR | $57,694,726 | Q33 | published | women: issues | Alexandria, VA | 2024 |
| GLOBAL ALLIANCE FOR VIKSIT BHARAT FOUNDATION | $56,992,787 | Q33 | published | | Bethlehem, PA | 2025 |
| BLUMONT GLOBAL DEVELOPMENT INC | $55,415,276 | Q33 | published | women: issues | Arlington, VA | 2024 |
| PURE HAND FOR MANKIND INC | $54,190,237 | Q33 | published | survivor: disaster | Plano, TX | 2025 |
| ORPHAN GRAIN TRAIN INC | $53,955,457 | Q33 | published | | Norfolk, NE | 2025 |
| LIFESONG FOR ORPHANS INC | $51,717,314 | Q33 | published | launch: religious | Gridley, IL | 2024 |
| PLAN INTERNATIONAL USA INC | $51,561,510 | Q33 | published | space: for women | Providence, RI | 2024 |
| UNRWA USA NATIONAL COMMITTEE INC | $51,495,126 | Q33 | published | shelter: disaster | Washington, DC | 2024 |
| RESULTS FOR DEVELOPMENT INSTITUTE INC | $49,137,699 | Q33 | published | violence: prevention | Washington, DC | 2024 |
| INTERNATIONAL RELIEF TEAMS | $48,733,515 | Q33 | published | shelter: disaster | San Diego, CA | 2024 |
| LIFE FOR RELIEF AND DEVELOPMENT INC | $47,271,328 | Q33 | published | shelter: disaster | Southfield, MI | 2024 |
| CHRISTIAN RELIEF SERVICES CHARITIES INC | $46,072,067 | Q33 | published | domestic violence | Alexandria, VA | 2024 |
| GRASSROOTS INTERNATIONAL INC | $41,686,332 | Q33 | published | domestic: workers | Boston, MA | 2024 |
| WORLDWIDE FRIENDS FOUNDATION | $39,889,046 | Q33 | published | | New York, NY | 2024 |
| ABRAHAMS BLESSING | $39,406,460 | Q33 | published | | Albany, NY | 2024 |
| DOULOS PARTNERS | $37,729,837 | Q33 | published | | Vestavia Hls, AL | 2024 |
| EVIDENCE ACTION INC | $36,213,681 | Q33 | published | | Washington, DC | 2024 |
| INTERNATIONAL CENTER FOR LIVING AQUATIC RESOURCES MANAGEMENT INC I | $34,793,000 | Q33 | inferred 0.60 | women: issues | Alexandria, VA | 2024 |
| RESOLVE UGANDA INCORPORATED | $34,530,806 | Q33 | published | science: research education | Washington, DC | 2024 |
| PLANET AID INC | $34,415,821 | Q33 | published | women: issues | Milford, MA | 2025 |
| RAZOM INC | $34,391,831 | Q33 | published | shelter: disaster | New York, NY | 2025 |
| UNTO INC | $34,139,194 | Q33 | published | | Orlando, FL | 2010 |
| INTERNATIONAL ORTHODOX CHRISTIAN CHARITIES INC | $33,856,667 | Q33 | published | shelter: disaster | Baltimore, MD | 2025 |
| MERCY WITHOUT LIMITS INC | $33,840,877 | Q33 | published | women: issues | Overland Park, KS | 2023 |
| HUMAN DEVELOPMENT FUND | $33,006,950 | Q33 | published | shelter: disaster | Canton, MI | 2024 |
| THE YONKOFA PROJECT INC | $32,080,416 | Q33 | published | | Peachtree Cty, GA | 2025 |
| CHILDREN INTERNATIONAL | $31,692,874 | Q33 | published | survivor: disaster | Kansas City, MO | 2024 |
| DASRA | $29,425,578 | Q33 | published | space: for women | Houston, TX | 2024 |
| CHRISTIAN RELIEF SERVICES CHARITIES INC | $26,580,348 | Q33 | published | launch: launch | Alexandria, VA | 2024 |
| LOVE A CHILD INC | $26,501,079 | Q33 | published | launch: launch | Fort Myers, FL | 2025 |
| COPTIC ORPHANS SUPPORT ASSOCIATION | $25,884,058 | Q33 | published | violence: sexual | Fairfax, VA | 2025 |
| INTERNATIONAL MEDICAL EQUIP COLL | $25,708,997 | Q33 | inferred 0.70 | | North Andover, MA | 2018 |
| HUMANITARIAN EXPERIENCE INC | $25,671,885 | Q33 | published | men: issues | Salt Lake Cty, UT | 2024 |
| GLOBAL OUTREACH INTERNATIONAL INC | $25,404,647 | Q33 | published | | Tupelo, MS | 2025 |
| LWALA COMMUNITY ALLIANCE INC | $25,162,456 | Q33 | published | | Nashville, TN | 2024 |
| LUKE COMMISSION INC | $24,902,960 | Q33 | published | violence: prevention | Sagle, ID | 2024 |
| ONECHILD GLOBAL | $23,971,006 | Q33 | published | | Colorado Spgs, CO | 2024 |
| INKOMOKO | $23,866,086 | Q33 | published | women: issues | Clinton, WA | 2025 |
| MARYS MEALS USA INC | $23,860,257 | Q33 | published | shelter: disaster | Bloomfield, NJ | 2025 |
| LIFTING HANDS INTERNATIONAL | $23,512,358 | Q33 | published | space: for women | Chandler, AZ | 2024 |
| GIVE2ASIA | $22,676,488 | Q33 | published | women: issues | San Francisco, CA | 2024 |
| ASSIST INTERNATIONAL INC | $21,083,313 | Q33 | published | survivor: disaster | Ripon, CA | 2024 |
| FRIENDS OF THE ORPHANS | $20,653,577 | Q33 | published | | Chicago, IL | 2024 |
| MERCURY ONE INC | $20,438,084 | Q33 | published | shelter: disaster | Irving, TX | 2025 |
| HEAL PALESTINE INC | $20,307,268 | Q33 | published | shelter: disaster | Kent, OH | 2024 |
| KIDS ALIVE INTERNATIONAL INC | $19,950,694 | Q33 | published | violence: prevention | Alpharetta, GA | 2024 |
| BARNABAS AID INTERNATIONAL | $19,861,801 | Q33 | published | | Lancaster, PA | 2024 |
| GIVING CHILDREN HOPE | $19,509,254 | Q33 | published | shelter: homeless | Buena Park, CA | 2024 |
| BRAVO FAMILY FOUNDATION | $19,331,616 | Q33 | published | | San Francisco, CA | 2024 |
| MISSION WITHOUT BORDERS INTERNATIONAL | $18,872,153 | Q33 | published | | Camarillo, CA | 2024 |
| VOLUNTEERS FOR ECONOMIC GROWTH ALLIANCE | $18,865,815 | Q33 | inferred 0.50 | | Washington, DC | 2018 |
| NRECA INTERNATIONAL LTD | $18,733,174 | Q33 | inferred 0.60 | | Arlington, VA | 2024 |
| HOPE OF LIFE INTERNATIONAL | $18,568,359 | Q33 | published | launch: religious | Cranston, RI | 2025 |
| WATERAID AMERICA INC | $18,473,150 | Q33 | published | science: research education | New York, NY | 2024 |
| CUSO INTERNATIONAL | $18,471,550 | Q33 | published | women: issues | Canada | 2025 |
| HEROIC HEARTS ORGANIZATION NFP | $16,877,818 | Q33 | published | shelter: disaster | Wheaton, IL | 2024 |
| VSK FOUNDATION | $16,820,758 | Q33 | published | women: issues | Manalapan, NJ | 2025 |
| REFUGEPOINT INC | $16,372,615 | Q33 | published | women: issues | Boston, MA | 2024 |
| IRIS GLOBAL | $15,887,186 | Q33 | published | abuse: child | Thompsons Stn, TN | 2024 |
| AFRICAN MISSION HEALTHCARE FOUNDATION | $15,536,832 | Q33 | published | launch: religious | Deland, FL | 2025 |
| MARANATHA VOLUNTEERS INTERNATIONAL INC | $15,227,905 | Q33 | published | launch: religious | Roseville, CA | 2025 |
| PREVAIL FOUNDRY INC | $15,069,398 | Q33 | published | | Madison, WI | 2024 |