| AMERICAN MEDICAL ASSOCIATION | $546,239,123 | H99 | inferred 0.80 | violence: gun | Chicago, IL | 2024 |
| INSTITUT PASTEUR | $409,245,392 | H99 | inferred 0.70 | science: research education | France | 2025 |
| THE RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE | $144,438,827 | H99 | inferred 0.80 | | Canada | 2025 |
| ASSOCIATION OF PUBLIC HEALTH LABORATORIES INC | $142,195,492 | H99 | inferred 0.70 | science: research education | Bethesda, MD | 2024 |
| ARC RESEARCH INSTITUTE | $122,280,682 | H99 | published | | Palo Alto, CA | 2024 |
| CITRUS RESEARCH AND DEVELOPMENT FOUNDATION INC | $105,546,288 | H99 | inferred 0.70 | science: research education | Lake Alfred, FL | 2025 |
| CHAN ZUCKERBERG BIOHUB INC | $99,552,025 | H99 | published | launch: launch | Redwood City, CA | 2024 |
| California Institute for BioMedical | $98,797,059 | H99 | inferred 0.80 | science: research education | La Jolla, CA | 2017 |
| LA JOLLA INSTITUTE FOR IMMUNOLOGY | $84,154,783 | H99 | inferred 0.85 | science: research education | La Jolla, CA | 2024 |
| INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH BANGLADESH | $77,723,739 | H99 | inferred 0.80 | science: research education | Bangladesh | 2024 |
| FUTURE CRYONICS FOUNDATION | $77,473,702 | H99 | published | science: research education | Cedar Rapids, IA | 2024 |
| ARKANSAS CHILDRENS HOSPITAL RESEARCH INSTITUTE | $71,774,036 | H99 | inferred 0.85 | science: research education | Little Rock, AR | 2024 |
| TRILOGY INC | $66,120,949 | H99 | inferred 0.60 | abuse: substance | Chicago, IL | 2024 |
| ABBOTT FUND | $55,570,056 | H99 | inferred 0.50 | abuse: sexual | Abbott Park, IL | 2024 |
| GEORGE S ECCLES AND DELORES DORE ECCLES FOUNDATION | $52,369,983 | H99 | inferred 0.60 | survivor: sexual | Salt Lake Cty, UT | 2024 |
| AMERICAN COLLEGE OF CHEST PHYSICIANS | $48,404,043 | H99 | inferred 0.80 | science: research education | Glenview, IL | 2025 |
| SIR MORTIMER B DAVIS JEWISH GENERAL HOSPITAL | $47,967,963 | H99 | inferred 0.70 | | Canada | 2024 |
| CRITICAL PATH INSTITUTE | $46,783,745 | H99 | published | launch: launch | Tucson, AZ | 2024 |
| HENDERSON-WESSENDORFF FOUNDATION | $44,288,793 | H99 | inferred 0.45 | girls boys: girl scouts | Richmond, TX | 2024 |
| EVERY CURE INC | $34,822,357 | H99 | published | | Philadelphia, PA | 2025 |
| TRANSCELERATE BIOPHARMA INC | $34,242,546 | H99 | published | launch: launch | West Conshohocken, PA | 2025 |
| RESEARCH CORPORATION | $29,142,107 | H99 | inferred 0.70 | space: outer | Tucson, AZ | 2024 |
| MEDICAL DEVICE INNOVATION CONSORTIUM | $28,171,331 | H99 | published | science: research education | Arlington, VA | 2024 |
| NATIONAL ALLIANCE FOR RESEARCH ON SCHIZOPHRENIA AND DEPRESSION INC | $27,686,049 | H99 | inferred 0.80 | science: research education | New York, NY | 2024 |
| SOUTHWEST AUTISM RESEARCH AND RESOURCE CENTER | $26,697,989 | H99 | published | science: research education | Phoenix, AZ | 2025 |
| FRAUNHOFER USA INC | $24,176,169 | H99 | published | science: research education | Plymouth, MI | 2024 |
| SKIN CANCER FOUNDATION INC | $20,751,484 | H99 | inferred 0.80 | | New York, NY | 2024 |
| ARBOR RESEARCH COLLABORATIVE FOR HEALTH | $20,353,298 | H99 | published | abuse: child | Ann Arbor, MI | 2024 |
| CALIFORNIA INSTITUTE FOR IMMUNOLOGY AND IMMUNOTHERAPY | $20,000,000 | H99 | published | science: research education | Los Angeles, CA | 2024 |
| GLENN FOUNDATION FOR MEDICAL RESEARCH INC | $19,842,299 | H99 | published | | Edmond, OK | 2024 |
| Rehabilitation Institute Research Corporation | $17,473,369 | H99 | inferred 0.60 | science: research education | Chicago, IL | 2010 |
| AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE | $16,725,749 | H99 | inferred 0.60 | science: research education | Washington, DC | 2024 |
| SANDERS TRI-INSTITUTIONAL THERAPEUT DISCOVERY INSTITUTE INC CO WEILL C | $16,577,142 | H99 | published | science: research education | New York, NY | 2024 |
| AMERICAN THROMBOSIS AND HEMOSTASISNETWORK INC | $15,982,317 | H99 | published | | Hickory, NC | 2024 |
| CLAYTON FOUNDATION FOR RESEARCH | $14,857,333 | H99 | published | science: research education | Houston, TX | 2024 |
| MEDICINES360 | $14,759,061 | H99 | published | women: issues | San Francisco, CA | 2024 |
| ZACHARY AND ELIZABETH M FISHER CENTER FOR ALZHEIMERS RESEARCH FDN | $14,515,618 | H99 | published | science: research education | New York, NY | 2024 |
| THE MIND RESEARCH NETWORK | $13,923,047 | H99 | inferred 0.70 | abuse: substance | Albuquerque, NM | 2018 |
| CENTER FOR INFORMATION AND STUDY ON CLINICAL RESEARCH PARTICIPATION | $13,860,918 | H99 | published | | Boston, MA | 2025 |
| INSTITUTE FOR MEDICAL RESEARCH INC | $13,751,223 | H99 | inferred 0.80 | survivor: cancer | Durham, NC | 2024 |
| WORTHAM FOUNDATION | $13,678,799 | H99 | inferred 0.60 | | Houston, TX | 2024 |
| COALITION OF CANCER COOPERATIVE GROUPS | $13,177,695 | H99 | published | science: research education | Philadelphia, PA | 2024 |
| FRIEDREICHS ATAXIA RESEARCH ALLIANCE FARA | $13,135,426 | H99 | published | launch: launch | Downingtown, PA | 2024 |
| NATIONAL DISEASE RESEARCH INTERCHANGE | $12,847,539 | H99 | published | science: research education | Philadelphia, PA | 2025 |
| ROSKAMP INSTITUTE INC | $12,659,194 | H99 | published | science: research education | Sarasota, FL | 2025 |
| FOOTBALL RESEARCH INC | $12,076,770 | H99 | published | | New York, NY | 2024 |
| HARRY S MOSS HEART TRUST | $11,591,505 | H99 | inferred 0.60 | women: issues | Dallas, TX | 2024 |
| HOUSE RESEARCH INSTITUTE | $11,238,984 | H99 | inferred 0.70 | | Los Angeles, CA | 2012 |
| JOHN S DUNN FOUNDATION | $11,144,127 | H99 | inferred 0.60 | abuse: sexual | Houston, TX | 2024 |
| ST FRANCIS RESEARCH AND EDUCATIONAL CORPORATION | $10,964,208 | H99 | inferred 0.80 | science: research education | Roslyn, NY | 2024 |
| AGRICULTURAL RESEARCH FOUNDATION | $10,714,308 | H99 | inferred 0.60 | | Corvallis, OR | 2024 |
| CENTER FOR HEALTHCARE RESEARCH & TRANSFORMATION | $10,522,026 | H99 | published | shelter: homeless | Ann Arbor, MI | 2024 |
| WHITEHALL FOUNDATION INC | $10,395,178 | H99 | inferred 0.55 | girls boys: boys | Palm Beach, FL | 2024 |
| LANKENAU INSTITUTE FOR MEDICAL RESEARCH | $9,978,219 | H99 | inferred 0.80 | science: research education | Radnor, PA | 2024 |
| INTERNATIONAL PARTNERSHIP FOR | $9,961,492 | H99 | inferred 0.70 | science: research education | Silver Spring, MD | 2022 |
| KY HOSPITAL RESEARCH & EDUCATION FOUNDATION INC | $9,958,781 | H99 | inferred 0.70 | | Louisville, KY | 2024 |
| RAY FOUNDATION INC | $9,577,031 | H99 | inferred 0.50 | launch: aviation | Naples, FL | 2024 |
| VERMONT OXFORD NETWORK INC | $9,545,556 | H99 | published | science: research education | Burlington, VT | 2024 |
| CEDARS SINAI INTELLECTUAL PROPERTY COMPANY | $9,424,010 | H99 | published | | W Hollywood, CA | 2024 |
| INTERNATIONAL ASSOCIATION FOR THE STUDY OF PAIN | $9,290,862 | H99 | inferred 0.70 | science: research education | Washington, DC | 2024 |
| AMERICAN LUNG ASSOCIATION OF THE | $9,116,355 | H99 | inferred 0.50 | women: issues | Phoenix, AZ | 2015 |
| AMERICAN ACADEMY OF HOSPICE & PALLIATIVE MEDICINE INC | $9,100,464 | H99 | inferred 0.50 | | Schaumburg, IL | 2024 |
| DR RALPH AND MARIAN FALK MEDICAL RESEARCH TRUST | $9,005,077 | H99 | inferred 0.80 | science: research education | Dallas, TX | 2024 |
| FOOD ALLERGY SCIENCE INITIATIVE INC | $8,942,516 | H99 | inferred 0.80 | science: research education | Boston, MA | 2024 |
| FUND FOR MEDICAL RESEARCH AND EDUCATION | $8,878,198 | H99 | inferred 0.80 | | Detroit, MI | 2024 |
| HARVEY W PETERS RESEARCH FOUNDATION | $8,816,927 | H99 | published | | Sioux Falls, SD | 2024 |
| FOUNDATION OF COGNITIVE THERAPY AND RESEARCH | $8,774,679 | H99 | inferred 0.80 | science: research education | Bala Cynwyd, PA | 2025 |
| BIOMEDICAL RESEARCH INSTITUTE OF NEW MEXICO | $8,334,379 | H99 | published | science: research education | Albuquerque, NM | 2024 |
| LARRY L HILLBLOM FOUNDATION INC | $8,223,952 | H99 | published | | Sonoma, CA | 2024 |
| ORTHOPEDIC TRAUMA ASSOCIATION INC | $8,150,038 | H99 | inferred 0.75 | science: research education | Schaumburg, IL | 2024 |
| USONA INSTITUTE INC | $7,949,536 | H99 | published | science: research education | Fitchburg, WI | 2024 |
| THE GEORGE E HEWITT FOUNDATION FOR MEDICAL RESEARCH | $7,937,758 | H99 | inferred 0.80 | | Newport Beach, CA | 2024 |
| SOCIETY OF TOXICOLOGY | $7,921,128 | H99 | inferred 0.70 | science: research education | Reston, VA | 2024 |
| GENESYS RESEARCH INSTITUTE INC FKA | $7,821,503 | H99 | inferred 0.60 | domestic violence | Brighton, MA | 2012 |
| DIASPORA HUMAN GENOMICS INSTITUTE | $7,760,072 | H99 | published | | Nashville, TN | 2024 |
| DRUGS AND DIAGNOSTICS FOR TROPICAL | $7,511,805 | H99 | published | | San Diego, CA | 2025 |
| INSTITUTE FOR PROTEIN INNOVATION INC | $7,481,529 | H99 | published | | Boston, MA | 2024 |
| MULTIDISCIPLINARY ASSOCIATION FOR PSYCHEDELIC STUDIES | $7,480,253 | H99 | published | abuse: sexual | Santa Clara, CA | 2024 |
| PACIFIC NORTHWEST RESEARCH INSTITUTE | $7,208,758 | H99 | published | | Seattle, WA | 2024 |
| DERMATOLOGY FOUNDATION | $7,193,686 | H99 | inferred 0.80 | science: research education | Skokie, IL | 2024 |
| CENTER FOR VETERANS RESEARCH AND EDUCATION | $7,139,520 | H99 | published | | Minneapolis, MN | 2025 |
| CHOLANGIOCARCINOMA FOUNDATION | $7,130,406 | H99 | published | science: research education | Salt Lake City, UT | 2024 |
| VIVLI INC | $6,896,288 | H99 | published | | Burlington, MA | 2024 |
| CHICAGO ASSOCIATION FOR RESEARCH AND EDUCATION IN SCIENCE | $6,852,172 | H99 | published | science: research education | Hines, IL | 2024 |
| INTERNATIONAL SOCIETY FOR STEM CELL RESEARCH | $6,758,250 | H99 | published | science: research education | Evanston, IL | 2025 |
| THE HEALTH COLLABORATIVE | $6,434,575 | H99 | published | | Cincinnati, OH | 2025 |
| OBESITY MEDICINE ASSOCIATION | $6,406,072 | H99 | inferred 0.60 | | Centennial, CO | 2024 |
| CARING CROSS INC | $6,365,843 | H99 | published | science: research education | Gaithersburg, MD | 2024 |
| SCOLIOSIS RESEARCH SOCIETY | $5,997,056 | H99 | inferred 0.80 | science: research education | Milwaukee, WI | 2024 |
| GENETICS SOCIETY OF AMERICA INCORPORATED | $5,909,178 | H99 | inferred 0.60 | | Rockville, MD | 2024 |
| ORENTREICH FOUNDATION FOR THE ADVANCEMENT OF SCIENCE INC | $5,694,632 | H99 | inferred 0.70 | science: research education | New York, NY | 2024 |
| FOUNDATION FOR ATLANTA VETERANS EDUCATION AND RESEARCH INC | $5,677,051 | H99 | inferred 0.70 | | Decatur, GA | 2025 |
| AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH | $5,667,449 | H99 | inferred 0.60 | science: research education | Washington, DC | 2024 |
| BRONX VETERANS MEDICAL RESEARCH FOUNDATION INC | $5,615,927 | H99 | inferred 0.85 | | Bronx, NY | 2025 |
| RICHMOND INSTITUTE FOR VETERANS RESEARCH | $5,542,579 | H99 | published | science: research education | Richmond, VA | 2025 |
| UNIVERSITY OF KENTUCKY MARKEY CANCER FOUNDATION INC | $5,526,266 | H99 | inferred 0.85 | women: issues | Lexington, KY | 2024 |
| PHARE BIO INC | $5,476,072 | H99 | published | | Boston, MA | 2024 |
| BIOMEDICAL ENGINEERING SOCIETY | $5,383,371 | H99 | inferred 0.80 | science: research education | Arlington, VA | 2024 |
| CLEVELAND VA MEDICAL RESEARCH AND EDUCATION FOUNDATION | $5,207,373 | H99 | published | science: research education | Cleveland, OH | 2025 |
| THOMAS N LYNN INSTITUTE FOR HEALTHCARE RESEARCH INC | $5,122,486 | H99 | published | men: issues | Oklahoma City, OK | 2024 |