| PARALYZED VETERANS OF AMERICA | $83,222,092 | H50 | published | science: research education | Washington, DC | 2024 |
| CHRISTOPHER REEVE FOUNDATION A NEW JERSEY NONPROFIT CORPORATION | $22,618,426 | H50 | published | science: research education | Short Hills, NJ | 2024 |
| CHILDRENS TUMOR FOUNDATION | $19,738,640 | H50 | published | science: research education | New York, NY | 2024 |
| JACOBS INSTITUTE INC | $13,903,778 | H50 | published | science: research education | Buffalo, NY | 2025 |
| CMT RESEARCH FOUNDATION INC | $8,662,522 | H50 | published | | Brookhaven, GA | 2024 |
| MANN MEDICAL RESEARCH ORGANIZATION | $7,305,685 | H50 | published | | San Fernando, CA | 2025 |
| ORTHOPAEDIC RESEARCH AND EDUCATION FOUNDATION | $4,671,069 | H50 | published | science: research education | Rosemont, IL | 2024 |
| AO NORTH AMERICA CHARITABLE FUND | $4,045,459 | H50 | published | | Wayne, PA | 2024 |
| CURE DUCHENNE | $3,941,885 | H50 | published | | Mission Viejo, CA | 2024 |
| MPN RESEARCH FOUNDATION | $3,585,445 | H50 | published | science: research education | Chicago, IL | 2024 |
| SETTING SCOLIOSIS STRAIGHT FOUNDATION | $2,745,752 | H50 | published | science: research education | El Cajon, CA | 2024 |
| ORTHOCAROLINA RESEARCH INSTITUTE INC | $2,643,097 | H50 | published | launch: religious | Charlotte, NC | 2024 |
| OSTEOGENESIS IMPERFECTA FOUNDATION INC | $2,607,851 | H50 | published | men: issues | Gaithersburg, MD | 2024 |
| ORTHOPAEDIC EDUCATION AND RESEARCH | $2,535,758 | H50 | published | | Orange, CA | 2023 |
| COLLABORATIVE TRAJECTORY ANALYSIS PROJECT | $1,887,913 | H50 | published | science: research education | Cambridge, MA | 2024 |
| PEDIATRIC SPINE FOUNDATION | $1,866,494 | H50 | published | | Layton, UT | 2024 |
| ORTHOPAEDIC FOUNDATION FOR ACTIVE LIFESTYLES INC | $1,595,536 | H50 | published | science: research education | Stamford, CT | 2024 |
| CHILD NEUROLOGY EDUCATION AND RESEARCH FOUNDATION | $1,263,681 | H50 | published | launch: launch | Hamilton, OH | 2024 |
| SPINE INSTITUTE OF LOUISIANA FOUNDATION INC | $1,243,749 | H50 | published | | Shreveport, LA | 2024 |
| ANTERIOR HIP FOUNDATION INC | $1,133,843 | H50 | published | | Vail, CO | 2025 |
| THE HAWKINS FOUNDATION | $1,112,291 | H50 | published | science: research education | Greenville, SC | 2025 |
| FELLOWSHIP OF ORTHOPEADIC RESEARCHERS INC | $1,070,923 | H50 | published | science: research education | Metairie, LA | 2025 |
| BIOENERGY FIELDS FOUNDATION | $1,043,305 | H50 | inferred 0.45 | | Austin, TX | 2024 |
| TWIN CITIES ORTHOPEDICS FOUNDATION | $881,422 | H50 | published | | Bloomington, MN | 2024 |
| KENNEDYS DISEASE ASSOCIATION | $745,674 | H50 | published | | Atlanta, GA | 2025 |
| CURE CMD INC | $677,234 | H50 | published | science: research education | Lakewood, CA | 2024 |
| INTERNATIONAL NEUROMODULATION SOCIETY | $653,817 | H50 | published | science: research education | San Francisco, CA | 2024 |
| SOUTHERN OREGON ORTHOPEDICS RESEARCH FOUNDATION | $639,335 | H50 | published | | Medford, OR | 2025 |
| CHARLEYS FUND INC | $628,496 | H50 | published | men: issues | Gt Barrington, MA | 2024 |
| THE INTERNATIONAL THYROID CANCER STUDY GROUP INC | $613,818 | H50 | published | science: research education | Yorkville, NY | 2025 |
| NEUROMUSCULAR STUDY GROUP INC | $588,959 | H50 | published | | Kansas City, KS | 2024 |
| MENTAL RESEARCH INSTITUTE | $537,330 | H50 | inferred 0.50 | abuse: child | Menlo Park, CA | 2025 |
| SOFT BONES INC THE US HYPOPHOSPHATASIA FOUNDATION | $526,669 | H50 | published | | Boonton, NJ | 2024 |
| FOUNDATION OF ORTHOPEDICS AND COMPLEX SPINE INC | $500,281 | H50 | published | | Garden City, NY | 2024 |
| NEW MEXICO HEALTH ENHANCEMENT AND MARATHON CLINICS RESEARCH FOUNDAT | $410,765 | H50 | published | | Albuquerque, NM | 2014 |
| DETERMINED2HEAL FOUNDATION INC | $409,320 | H50 | published | | Potomac, MD | 2024 |
| HINRI LABS INC | $371,810 | H50 | published | | Atlanta, GA | 2024 |
| BEACON ORTHOPAEDIC RESEARCH & EDUCATION FOUNDATION | $341,518 | H50 | published | | Cincinnati, OH | 2024 |
| AMERICAN SOCIETY FOR PERIPHERAL NERVE | $316,371 | H50 | published | science: research education | Beverly, MA | 2024 |
| KERLAN-JOBE ORTHOPAEDIC FOUNDATION | $313,075 | H50 | published | | Beverly Hills, CA | 2025 |
| EMPOWER SPINAL CORD INJURY INCORPORATED | $310,367 | H50 | published | | Waltham, MA | 2024 |
| CARRELL CLINIC FOUNDATION | $299,267 | H50 | published | | Dallas, TX | 2024 |
| NATIONAL BONE MARROW TRANSPLANT LINK | $290,191 | H50 | published | survivor: cancer | Commerce Twp, MI | 2024 |
| LOUISVILLE ORTHOPEDIC RESEARCH & EDUCATIONAL FOUNDATION INC | $282,185 | H50 | published | | Louisville, KY | 2024 |
| INDIANA PARKINSON FOUNDATION | $261,692 | H50 | published | | Noblesville, IN | 2025 |
| DENNISON CHARITABLE FOUNDATION INC | $256,952 | H50 | published | | Lakeville, MA | 2025 |
| TARLOV CYST DISEASE FOUNDATION | $249,987 | H50 | published | science: research education | Knoxville, TN | 2025 |
| LEPTOMENINGEAL CANCER FOUNDATION | $216,305 | H50 | published | | Broomfield, CO | 2025 |
| AUDRE LORDE PROJECT INC | $211,917 | H50 | published | | Brooklyn, NY | 2024 |
| GIVING STRENGTH INC | $203,911 | H50 | published | | Fulton, MD | 2024 |
| TENNESSEE ORTHOPAEDIC FOUNDATION FOR EDUCATION AND RESEARCH TOFER | $199,999 | H50 | published | science: research education | Brentwood, TN | 2024 |
| MARS RESEARCH INC | $188,599 | H50 | published | | Gilbert, IA | 2025 |
| BIODYNAMIC CRANIOSACRAL THERAPY ASSOCIATION OF NORTH AMERICA | $188,166 | H50 | published | | Aurora, OH | 2024 |
| CENTER FOR NEUROSCIENCES FOUNDATION | $171,746 | H50 | published | girls boys: girl scouts | Tucson, AZ | 2024 |
| INTERNATIONAL CONSENSUS MEETING ON INFECTION | $169,983 | H50 | published | | Philadelphia, PA | 2024 |
| RYANS LAKE HUNTING & FISHING CLUB | $165,400 | H50 | published | | Lufkin, TX | 2024 |
| TEXAS HIP AND KNEE FOUNDATION | $159,459 | H50 | published | | Fort Worth, TX | 2024 |
| HIBM RESEARCH GROUP INC | $142,698 | H50 | published | | Calabasas, CA | 2015 |
| ILLINOIS ORTHOPAEDIC FOUNDATION | $136,883 | H50 | published | | Glenview, IL | 2024 |
| ALS CURE PROJECT INC | $133,389 | H50 | published | science: research education | Pleasanton, CA | 2025 |
| AMERICAN SPINAL RESEARCH ORGANIZATION INCORPORATED | $127,050 | H50 | published | science: research education | Columbus, OH | 2024 |
| OCI HEALING RESEARCH FOUNDATION INC | $126,600 | H50 | published | | Quincy, MA | 2025 |
| NORTH STAR ALS INC | $121,787 | H50 | published | science: research education | Santa Barbara, CA | 2025 |
| CALIFORNIA TRAUMA RESEARCH FOUNDATION | $110,857 | H50 | published | | Cerritos, CA | 2024 |
| SKINTELLAGENT DERMATOLOGY UNDRESSED | $107,810 | H50 | published | | Phoenix, AZ | 2025 |
| JOSHUAS FUTURE OF PROMISES INC | $106,196 | H50 | published | | Emmaus, PA | 2024 |
| FOUNDATION FOR ARTHROPLASTY RESEARCH AND EDUCATION | $103,998 | H50 | published | science: research education | Rosemont, IL | 2024 |
| NEUROLINX RESEARCH INSTITUTE | $101,120 | H50 | published | | La Jolla, CA | 2025 |
| ALEX REZKALLA FOUNDATION | $90,567 | H50 | published | science: research education | Powell, OH | 2024 |
| SCIENTIFIC EDUCATION & RESEARCH FOUNDATION | $89,881 | H50 | published | science: research education | Thornton, CO | 2024 |
| TRI-STATE MULTIPLE SCLEROSIS ASSOCIATION INC | $89,686 | H50 | published | | Evansville, IN | 2025 |
| SPINE AND SCOLIOSIS RESEARCH ASSOCIATES INC | $84,119 | H50 | published | | Coral Gables, FL | 2024 |
| INTERNATIONAL WORKSHOP ON RESISTANCE TO THYROID HORMONE | $80,378 | H50 | published | science: research education | Mc Chicago, IL | 2016 |
| LGMD2L FOUNDATION | $78,539 | H50 | published | | Park Ridge, IL | 2025 |
| EDUCATION AND RESEARCH FOUNDATION | $75,989 | H50 | published | | Columbia, SC | 2025 |
| WOBBLY FEET FOUNDATION INC | $74,449 | H50 | published | science: research education | Sarasota, FL | 2022 |
| JORDAN RESEARCH FOUNDATION | $73,954 | H50 | published | | Virginia Bch, VA | 2025 |
| MEDICAL TOXICOLOGY RESEARCH INC | $71,333 | H50 | published | | Phoenix, AZ | 2024 |
| FOX IN THE D | $70,161 | H50 | published | | Novi, MI | 2025 |
| MEDS 1 MEDICAL RESEARCH | $67,672 | H50 | published | | Los Angeles, CA | 2024 |
| MARTIN A TURBIDE MS FOUNDATION INC | $59,874 | H50 | published | | Fitchburg, MA | 2025 |
| PACIFIC RAILCAR OPERATORS | $59,265 | H50 | published | | Elmira, OR | 2025 |
| KELLY ALLARD LEACH FOUNDATION FOR CHILDREN WITH SPINAL INJURIES INC | $57,981 | H50 | published | | Killingworth, CT | 2025 |
| ASPEN FOUNDATION FOR SPORTS MEDICINE EDUCATION AND RESEARCH | $53,235 | H50 | published | | Basalt, CO | 2025 |
| CARTILAGE RESEARCH FOUNDATION INC | $39,886 | H50 | published | science: research education | Morgantown, IN | 2024 |
| STEVEN PREWITT SKULL BASE DISEASE FOUNDATION | $39,246 | H50 | published | survivor: cancer | San Diego, CA | 2025 |
| FOUNDATION FOR ADVANCEMENT OF SPINAL KNOWLEDGE | $37,834 | H50 | published | science: research education | Minneapolis, MN | 2025 |
| INSTITUTE FOR SPORTS MEDICINE RESEARCH | $37,500 | H50 | published | science: research education | Lee Center, NY | 2019 |
| ALS CARE PROJECT | $34,811 | H50 | published | | Canton, OH | 2022 |
| ORTHOPAEDIC RESEARCH FOUNDATION OF SOUTHERN ILLINOIS | $32,207 | H50 | published | | Cocoa Beach, FL | 2025 |
| JOHN LACHMAN ORTHOPEDIC RESEARCH FUND INC | $31,187 | H50 | published | | Philadelphia, PA | 2025 |
| INTERNATIONAL CELLULAR MEDICINE SOCIETY | $30,371 | H50 | published | science: research education | Las Vegas, NV | 2024 |
| CAROLINA ORTHOPAEDIC RESEARCH FOUNDATION | $28,889 | H50 | published | | Greenville, SC | 2024 |
| THE GEORGIA FOUNDATION FOR PHYSICAL THERAPY INC | $26,823 | H50 | published | | Henrico, VA | 2025 |
| CINCINNATI SHOULDER AND ELBOW RESEARCH AND EDUCATION FOUNDATION | $23,080 | H50 | published | | Edgewood, KY | 2024 |
| BENNETT CLAYTON FOUNDATION FOR CHILDREN WITH OI | $15,775 | H50 | published | | St Peter, MN | 2025 |
| 360 WHITEHALL HOUSING DEVELOPMENT FUND CORP | $14,582 | H50 | published | | Albany, NY | 2024 |
| ROAD GEMS CAR CLUB INC | $13,544 | H50 | published | | West Point, NE | 2025 |
| AMERICAN FOUNDATION OF MEDICAL ACUPUNCTURE | $10,857 | H50 | inferred 0.70 | | Redondo Beach, CA | 2024 |
| GEOFFREY BEENE FOUNDATION ALZHEIMERS | $10,011 | H50 | inferred 0.75 | women: issues | New York, NY | 2019 |