| LEDUCQ FOUNDATION FOR CARDIOVASCULAR RESEARCH | $40,540,832 | H43 | published | | Houston, TX | 2024 |
| TEXAS HEART INSTITUTE | $24,749,411 | H43 | published | | Houston, TX | 2024 |
| MINNEAPOLIS HEART INSTITUTE FOUNDATION | $23,641,948 | H43 | published | girls boys: girl scouts | Minneapolis, MN | 2024 |
| CVPATH INSTITUTE INC | $13,092,271 | H43 | published | | Gaithersburg, MD | 2024 |
| HERITAGE MEDICAL RESEARCH INSTITUTE | $10,077,694 | H43 | published | science: research education | Bakersfield, CA | 2024 |
| HEART FAILURE SOCIETY OF AMERICA INC | $9,459,756 | H43 | published | science: research education | Rockville, MD | 2025 |
| HEALTHCORPS INC | $4,969,810 | H43 | published | | New York, NY | 2024 |
| PRAIRIE RESEARCH AND EDUCATION COOPERATIVE | $3,044,537 | H43 | published | | Springfield, IL | 2024 |
| METHODIST RESEARCH INSTITUTE INC | $2,707,760 | H43 | inferred 0.80 | science: research education | Indianapolis, IN | 2017 |
| SOCIETY OF INTERVENTIONAL RADIOLOGY FOUNDATION | $2,277,245 | H43 | published | science: research education | Fairfax, VA | 2024 |
| OKLAHOMA HEART RESEARCH AND EDUCATION FOUNDATION | $2,050,514 | H43 | published | | Tulsa, OK | 2024 |
| PREVENTIVE MEDICINE RESEARCH INSTITUTE | $1,302,779 | H43 | published | science: research education | Sausalito, CA | 2024 |
| JOHNSIE & AUBARY MONTGOMERYINSTITUTE OF MED EDU & RESEARCH INC | $1,228,464 | H43 | published | women: issues | Houston, TX | 2023 |
| INTERNATIONAL ANDREAS GRUENTZIG SOCIETY | $1,141,322 | H43 | published | science: research education | San Francisco, CA | 2025 |
| INTERNATIONAL SOCIETY FOR MINIMALLY INVASIVE CARDIAC SURGERY | $1,115,168 | H43 | published | science: research education | Beverly, MA | 2024 |
| NATIONAL BLOOD CLOT ALLIANCE | $995,453 | H43 | published | women: issues | Philadelphia, PA | 2024 |
| OKLAHOMA HEART HOSPITAL RESEARCH FOUNDATION | $907,178 | H43 | published | science: research education | Oklahoma City, OK | 2024 |
| KANSAS CITY HEARTRHYTM RESEARCH FOUNDATION | $738,127 | H43 | published | | Overland Park, KS | 2024 |
| TRANSPLANTS ORG INC | $717,911 | H43 | published | science: research education | Washington, DC | 2025 |
| MIDWEST CARDIOVASCULAR RESEARCH AND EDUCATION FOUNDATION | $633,209 | H43 | published | shelter: homeless | Elkhart, IN | 2025 |
| HEARTS IN HARMONY FOUNDATION | $506,187 | H43 | published | | Westport, CT | 2024 |
| WESTERN CARDIAC FOUNDATION | $498,395 | H43 | inferred 0.55 | | Sherman Oaks, CA | 2024 |
| HYPERTENSION INSTITUTE FOUNDATION | $485,137 | H43 | published | | Franklin, TN | 2024 |
| CARDIAC SAFETY RESEARCH CONSORTIUM | $477,303 | H43 | published | | Narberth, PA | 2025 |
| CARDIOVASCULAR RESEARCH AND EDUCATION | $455,447 | H43 | inferred 0.60 | | Indianapolis, IN | 2010 |
| PULMONARY WELLNESS FOUNDATION INC | $452,529 | H43 | published | science: research education | New York, NY | 2024 |
| HARLAN E MOORE HEART RESEARCH FOUNDATION | $439,601 | H43 | published | | Champaign, IL | 2025 |
| CHAMPIONSHIP HEARTS FOUNDATION | $349,433 | H43 | published | | Manor, TX | 2024 |
| EAR RESEARCH FOUNDATION INC | $346,099 | H43 | inferred 0.60 | | Sarasota, FL | 2024 |
| FLORIDA HEART RESEARCH FOUNDATION INC | $344,246 | H43 | published | science: research education | Miami, FL | 2025 |
| CENTER FOR BIOMEDICAL SCIENCE AND ENGINEERING TRUST | $308,738 | H43 | published | science: research education | Brookline, MA | 2024 |
| HOUSTON SHOCK SYMPOSIUM | $297,587 | H43 | published | | Houston, TX | 2024 |
| CONQUERING CONGENITAL HEART DISEASE | $291,957 | H43 | published | | Middleton, WI | 2023 |
| FOUNDATION FOR CARDIOVASCULAR MEDICINE AND RESEARCH | $289,213 | H43 | published | | San Diego, CA | 2024 |
| VIRGINIA CARDIAC SERVICES QUALITY INITIATIVE | $258,849 | H43 | published | | South Riding, VA | 2025 |
| SICKLE CELL FOUNDATION OF ARIZONA INC | $237,140 | H43 | published | | Tucson, AZ | 2024 |
| PHAWARE GLOBAL ASSOCIATION | $224,214 | H43 | published | | Burbank, CA | 2024 |
| INTERNATIONAL PEDIATRIC STROKE ORGANIZATION INC | $223,516 | H43 | published | | San Francisco, CA | 2024 |
| ISCHEMIA RESEARCH & EDUCATION FOUNDATION | $222,230 | H43 | published | | Hillsborough, CA | 2024 |
| FETAL HEART SOCIETY INC | $215,476 | H43 | published | science: research education | Roseville, MN | 2024 |
| CORDAY FAMILY FOUNDATION | $213,299 | H43 | published | | Los Angeles, CA | 2025 |
| INTERNATIONAL SOCIETY FOR CARDIOVASCULAR TRANSLATIONAL RESEA | $210,897 | H43 | published | | Phoenix, AZ | 2025 |
| FOUNDATION OF THE NATIONAL LIPID ASSOCIATION INC | $204,990 | H43 | published | | Jacksonville, FL | 2025 |
| STATEN ISLAND HEART SOCIETY INC | $197,067 | H43 | published | | Staten Island, NY | 2025 |
| ADVANCES IN CONTRAST ULTRASOUND NFP | $194,373 | H43 | published | | Chicago, IL | 2024 |
| HEART OF PPA2 INC | $192,233 | H43 | published | | Hauppauge, NY | 2025 |
| ADAMS VALVE FOUNDATION | $188,065 | H43 | published | | Reston, VA | 2025 |
| INTERVENTIONAL CARDIOLOGY RESEARCH FOUNDATION | $181,111 | H43 | published | science: research education | Metairie, LA | 2024 |
| THORACIC CONNECT FOUNDATION | $170,541 | H43 | published | | Tampa, FL | 2025 |
| CONQUERING CONGENITAL HEART DISEASE | $150,638 | H43 | published | | Snohomish, WA | 2019 |
| MELVIN SCHEINMAN EDUCATIONAL RHYTHM FOUNDATION | $148,115 | H43 | published | | Morrison, CO | 2025 |
| SUDDEN CARDIAC-DEATH AWARENESS RESEARCH FOUNDATION | $138,671 | H43 | published | | Sycamore, IL | 2025 |
| RETINAL VASCULAR FOUNDATION | $126,600 | H43 | inferred 0.60 | | Pepper Pike, OH | 2025 |
| MEDVANTAGE RESEARCH INC | $125,450 | H43 | published | science: research education | Rocklin, CA | 2025 |
| DESERT HEART FOUNDATION | $125,100 | H43 | published | | Tucson, AZ | 2014 |
| HEART AND STROKE RESEARCH FUND | $112,297 | H43 | published | | Scottsdale, AZ | 2024 |
| INTERNATIONAL SOCIETY FOR HEART RESEARCH AMERICAN SECTION INC | $109,094 | H43 | published | | Boston, MA | 2025 |
| WOMENS HORMONE NETWORK | $103,505 | H43 | published | women: issues | Santa Barbara, CA | 2025 |
| CARDIOVASCULAR & IMAGING RESEARCH FOUNDATION OF NY | $103,198 | H43 | published | | Lloyd Harbor, NY | 2025 |
| NEW YORK SOCIETY FOR SURGERY OF THE HAND INC | $102,764 | H43 | inferred 0.60 | | New York, NY | 2025 |
| FRIENDS OF THE FRAMINGHAM HEART STUDY INC | $102,300 | H43 | published | | Framingham, MA | 2025 |
| HEARTS FOR RUSS INC | $88,095 | H43 | published | | South Salem, NY | 2025 |
| TWIN CITIES HEART FOUNDATION | $86,264 | H43 | published | | Minneapolis, MN | 2024 |
| STUDENTS RUN CHICAGO | $78,105 | H43 | published | | Chicago, IL | 2024 |
| CARDIAC SURGERY CLINICAL RESEARCH CENTER INC | $77,089 | H43 | published | | Oakbrook Ter, IL | 2025 |
| HOPE HEART INSTITUTE | $77,044 | H43 | published | science: research education | Redmond, WA | 2024 |
| ANGELS FOR HEARTS | $76,836 | H43 | published | | Sacramento, CA | 2025 |
| WITTEK RESEARCH FOUNDATION FOR HYPERTROPHIC CARDIOMYOPATHY INC | $73,921 | H43 | published | | Tenafly, NJ | 2023 |
| WAUKESHA HEART FOUNDATION INC | $69,517 | H43 | published | | Fort Myers, FL | 2016 |
| CONQUERING CONGENITAL HEART DISEASE | $65,577 | H43 | published | | Manheim, PA | 2022 |
| FOUNDATION FOR HEART SCIENCE LTD | $65,350 | H43 | published | science: research education | Wawautosa, WI | 2025 |
| HEART DISEASE RESEARCH FOUNDATION | $61,837 | H43 | published | | Manhattan Bch, CA | 2024 |
| BLUE LIPS FOUNDATION | $60,108 | H43 | published | | Urbandale, IA | 2023 |
| PULMONARY PATHOLOGY SOCIETY INC | $57,930 | H43 | published | | Scottsdale, AZ | 2024 |
| SAVE A HEART FOUNDATION | $54,381 | H43 | published | | Los Angeles, CA | 2024 |
| HOUSTEN CENTER FOR VASCULAR HEALTH | $47,481 | H43 | published | | Houston, TX | 2016 |
| WORLD HEART FOUNDATION | $45,968 | H43 | inferred 0.80 | science: research education | Denver, CO | 2011 |
| HOPEYS HEART FOUNDATION | $43,446 | H43 | published | | Baldwin, NY | 2022 |
| METROPOLITAN CARDIOLOGY CONSULTANTS RESEARCH AND EDUCATION FOUNDATION | $35,154 | H43 | published | | Coon Rapids, MN | 2025 |
| SEMLER INSTITUE FOR STRESS MANAGEMENT RESEARCH AND EDUCATION | $31,375 | H43 | published | | San Francisco, CA | 2024 |
| PIMA HEART RESEARCH FOUNDATION | $30,001 | H43 | published | | Tucson, AZ | 2010 |
| DELAWARE VALLEY STS QUALITY IMPROVEMENT INITIATIVE | $29,296 | H43 | published | | West Chester, PA | 2017 |
| THE CARDIOVASCULAR MEDICAL RESEARCH AND | $29,175 | H43 | inferred 0.70 | science: research education | King Of Prussia, PA | 2025 |
| STUART P MILLER TR FBO CHARLOTTE BOATNER | $28,313 | H43 | published | | Saint Louis, MO | 2025 |
| PIKE COUNTY HEART BOARD | $20,323 | H43 | published | | Troy, AL | 2024 |
| METRO CARDIOVASCULAR RESEARCH FOUNDATION INC | $15,564 | H43 | published | | Cleveland, OH | 2025 |
| NORTHERN ILLINOIS HEART INSTITUTE INC | $15,528 | H43 | published | | Elgin, IL | 2025 |
| ELECTRO CARDIOGRAPHIC HEARTBEAT ORGANIZATION | $14,709 | H43 | published | | Los Angeles, CA | 2024 |
| QUINN DRISCOLL FOUNDATION | $14,649 | H43 | published | | Vancouver, WA | 2013 |
| MASONS GIVE A HEART FOUNDATION INC | $12,637 | H43 | published | | Raymore, MO | 2025 |
| CARDIAC ELECTROPHYSIOLOGY SOCIETY | $11,550 | H43 | inferred 0.70 | science: research education | Utica, NY | 2025 |
| PALEOCARDIOLOGY FOUNDATION | $11,000 | H43 | published | | Dana Point, CA | 2025 |
| CARDIOVASCULAR RESEARCH FOUNDATION INC | $10,517 | H43 | published | | Owensboro, KY | 2025 |
| EP LIVE FOUNDATION | $10,000 | H43 | published | | Overland Park, KS | 2025 |
| ST FRANCES CABRINI HEART FOUNDATION | $9,116 | H43 | published | | Preston, ID | 2025 |
| CARDIOLOGY ASSOCIATES FOUNDATION | $6,313 | H43 | published | women: issues | New York, NY | 2024 |
| POTS RESEARCH TRUST FUND | $6,066 | H43 | published | | Myerstown, PA | 2025 |
| NEVER MISS A BEAT FOUNDATION | $5,950 | H43 | published | | Yardley, PA | 2024 |
| JASON F GRUEN RESEARCH FOUNDATION INC | $5,665 | H43 | inferred 0.60 | | East Meadow, NY | 2011 |
| UNIVERSITY EMERGENCY MEDICINE ASSOCIATES INC | $5,165 | H43 | inferred 0.70 | | Indianapolis, IN | 2013 |