| DEAN MCGEE EYE INSTITUTE | $53,585,210 | H41 | published | | Oklahoma City, OK | 2024 |
| FOUNDATION FIGHTING BLINDNESS INC | $36,615,169 | H41 | published | science: research education | Columbia, MD | 2024 |
| EYE & EAR FOUNDATION INC | $13,522,523 | H41 | published | science: research education | Pittsburgh, PA | 2024 |
| A RACE AGAINST BLINDNESS | $12,464,243 | H41 | published | | Gilbert, AZ | 2024 |
| PROJECT VISION HAWAII | $11,918,174 | H41 | published | science: research education | Honolulu, HI | 2024 |
| RETINA FOUNDATION OF THE SOUTHWEST | $11,477,798 | H41 | published | science: research education | Dallas, TX | 2025 |
| GLAUCOMA RESEARCH FOUNDATION | $10,127,426 | H41 | published | science: research education | San Francisco, CA | 2024 |
| OPHTHALMOLOGY RESEARCH FOUNDATION INC | $8,505,316 | H41 | published | science: research education | Miami, FL | 2024 |
| THAT MAN MAY SEE INC | $6,889,735 | H41 | published | | San Francisco, CA | 2024 |
| RESEARCH TO PREVENT BLINDNESS INC | $6,824,102 | H41 | published | science: research education | New York, NY | 2024 |
| THE LOWY MEDICAL RESEARCH INSTITUTE INC | $6,571,459 | H41 | published | science: research education | La Jolla, CA | 2024 |
| THE SMITH-KETTLEWELL EYE RESEARCH INSTITUTE | $5,438,042 | H41 | inferred 0.85 | science: research education | San Francisco, CA | 2024 |
| ARTHRITIS NATIONAL RESEARCH FOUNDATION | $4,662,015 | H41 | published | science: research education | Irvine, CA | 2024 |
| RETINA RESEARCH FOUNDATION | $3,168,044 | H41 | published | | Houston, TX | 2024 |
| AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY & STRABISMUS | $2,442,959 | H41 | published | | Brentwood, TN | 2024 |
| MACULA FOUNDATION INC | $1,891,816 | H41 | published | | New York, NY | 2024 |
| COLLABORATIVE COMMUNITY ON OPHTHALMIC INNOVATION FOUNDATION | $1,619,910 | H41 | published | | Reston, VA | 2025 |
| OCULAR IMMUNOLOGY AND UVEITIS FOUNDATION INC | $1,565,787 | H41 | published | science: research education | Weston, MA | 2024 |
| ODYLIA THERAPEUTICS INC | $1,523,364 | H41 | published | | Atlanta, GA | 2025 |
| ALAGILLE SYNDROME ALLIANCE | $1,165,369 | H41 | published | science: research education | Washington, DC | 2025 |
| BENIGN ESSENTIAL BLEPHAROSPASM RESEARCH FOUNDATION INC | $1,127,227 | H41 | published | | Beaumont, TX | 2025 |
| MASSACHUSETTS LIONS EYE RESEARCH FUND INC | $1,024,397 | H41 | published | | Millis, MA | 2024 |
| CINCINNATI EYE INSTITUTE FOUNDATION | $959,816 | H41 | published | science: research education | Blue Ash, OH | 2024 |
| VISUAL STUDIES WORKSHOP INC | $934,803 | H41 | published | | Rochester, NY | 2024 |
| FOUNDATION FOR VISION RESEARCH | $931,107 | H41 | published | | Grand Rapids, MI | 2024 |
| HERMANN EYE FUND | $913,870 | H41 | published | science: research education | Houston, TX | 2024 |
| ENSIGHT SKILL CENTER | $688,795 | H41 | published | | Fort Collins, CO | 2024 |
| CONNECTICUT LIONS EYE RESEARCH FOUNDATION INC | $677,147 | H41 | inferred 0.80 | | Watertown, CT | 2024 |
| ZERO BLIND BABIES | $653,299 | H41 | published | | Powell, OH | 2024 |
| GLOBAL OPHTHALMIC RESEARCH CENTER | $637,741 | H41 | published | | Los Altos, CA | 2025 |
| HERMAN KNAPP TESTAMONIAL FUND | $480,737 | H41 | published | science: research education | San Francisco, CA | 2024 |
| CHARLESSON FOUNDATION | $479,044 | H41 | published | science: research education | Lewisville, NC | 2024 |
| EYE AND CONTACT LENS FOUNDATION | $477,560 | H41 | published | | Centennial, CO | 2025 |
| TEAR FILM AND OCULAR SURFACE SOCIETY INC | $474,008 | H41 | published | science: research education | Boston, MA | 2024 |
| CHRISTIAN OPHTHALMOLOGY SOCIETY INC | $386,436 | H41 | published | | Paducah, KY | 2024 |
| MARGARET S MAHLER CHILD DEVELOPMENT FOUNDATION | $373,516 | H41 | inferred 0.60 | | Wynnewood, PA | 2024 |
| FACULTY STUDENT ASSOCIATION OF THE STATE COLLEGE OF OPTOMETRY INC | $360,010 | H41 | published | | New York, NY | 2025 |
| THOMAS HEED OPHTHALMIC FOUNDATION 2620066500 | $346,393 | H41 | inferred 0.75 | | Boston, MA | 2025 |
| TARRANT EYE RESOURCES INC | $345,902 | H41 | published | | Fort Worth, TX | 2024 |
| PEDIATRIC KERATOPLASTY FOUNDATION INC | $318,270 | H41 | published | | Harrison, NY | 2025 |
| INTERNATIONAL SOCIETY FOR CONTACT LENS RESEARCH | $303,119 | H41 | published | science: research education | Saint Louis, MO | 2024 |
| FLAGELLA VISION FOUNDATION | $302,839 | H41 | published | | Woodbury, MN | 2024 |
| BETTER VISION FOR CHILDREN | $292,546 | H41 | published | | Mission Viejo, CA | 2024 |
| KIZUNA FOUNDATION | $260,821 | H41 | published | | Scottsdale, AZ | 2025 |
| OPTOMETRIC GLAUCOMA SOCIETY | $224,894 | H41 | published | science: research education | Lawrence, KS | 2025 |
| GLAUCOMA SERVICE FOUNDATION TO | $208,843 | H41 | inferred 0.80 | | Philadelphia, PA | 2016 |
| GULANI VISON GLOBAL FOUNDATION INC | $206,026 | H41 | published | | Jacksonville, FL | 2025 |
| OHIO LIONS EYE RESEARCH FOUNDATION | $194,061 | H41 | published | | Ashland, OH | 2024 |
| VMR RESEARCH FOUNDATION | $191,691 | H41 | published | science: research education | Laguna Beach, CA | 2024 |
| MULTIPLE DISTRICT 22 LIONS VISION RESEARCH FOUNDATION INC | $158,100 | H41 | published | | Baltimore, MD | 2024 |
| PEDIATRIC RETINAL RESEARCH FOUNDATION | $153,946 | H41 | published | | Warren, MI | 2024 |
| MINNESOTA EYE FOUNDATION | $145,942 | H41 | published | launch: religious | Minnetonka, MN | 2024 |
| CENTER FOR EYE RESEARCH INC | $124,309 | H41 | published | science: research education | Waltham, MA | 2024 |
| HEAR SEE HOPE | $110,064 | H41 | published | science: research education | Bellevue, WA | 2025 |
| WOLFE CATARACT FOUNDATION | $93,700 | H41 | inferred 0.50 | | Marshalltown, IA | 2024 |
| VISILANT INC | $93,224 | H41 | published | | Baltimore, MD | 2024 |
| PEDIATRIC VISION RESEARCH AND DIAGNOSTIC CENTER | $89,520 | H41 | published | | Fort Worth, TX | 2024 |
| OPHTHALMICEDGE INC | $87,912 | H41 | published | | New York, NY | 2025 |
| AMERICAN OPHTHLMOLOGICAL SOCIETY CH ARITABLE EDUCATIONA & SCIENTIFIC | $80,176 | H41 | published | science: research education | San Francisco, CA | 2024 |
| LUPUS FOUNDATION OF AMERICA | $77,522 | H41 | inferred 0.90 | | Peoria, AZ | 2009 |
| ERNEST C & YVETTE C VILLERE CHAIR FOR | $76,859 | H41 | inferred 0.80 | science: research education | New Orleans, LA | 2013 |
| THE CHILD HEALTH FOUNDATION | $76,625 | H41 | inferred 0.50 | | Birmingham, AL | 2025 |
| GLAUCOMA INSTITUTE OF BEVERLY HILLS RESEARCH FOUNDATION INC | $76,571 | H41 | published | | Beverly Hills, CA | 2024 |
| VISION RESEARCH INSTITUTE | $68,963 | H41 | published | science: research education | Lexington, MA | 2025 |
| CALIFORNIA RETINA RESEARCH FOUNDATION | $68,040 | H41 | published | | Santa Barbara, CA | 2024 |
| STRABISMUS RESEARCH FOUNDATION | $67,596 | H41 | published | | Mill Valley, CA | 2024 |
| THE MEGAN FOUNDATION INC | $63,108 | H41 | inferred 0.85 | | Saint Louis, MO | 2014 |
| KINO-EYE CENTERE FOR VISUAL INNOVATION | $62,011 | H41 | published | science: research education | Houston, TX | 2022 |
| ADVANCED RETINAL THERAPEUTICS INSTITUTE | $54,937 | H41 | published | | Pensacola, FL | 2024 |
| THE GLAUCOMA EDUCATION & RESEARCH FUND INC | $45,034 | H41 | published | | New York, NY | 2024 |
| MELLES RESEARCH FOUNDATION USA INC | $38,186 | H41 | published | | San Diego, CA | 2025 |
| JACKSON ORTHOPAEDIC FOUNDATION | $37,564 | H41 | published | women: issues | Oakland, CA | 2025 |
| CHICAGO CENTER FOR VISION RESEARCH LTD | $32,461 | H41 | published | science: research education | Chicago, IL | 2024 |
| O J NOER RESEARCH FOUNDATION INC | $25,617 | H41 | inferred 0.80 | science: research education | Mukwonago, WI | 2019 |
| VITREORETINAL AND MACULA RESEARCH FOUNDATION INC | $25,507 | H41 | published | science: research education | Tampa, FL | 2025 |
| CURE FOR BLINDNESS INC | $25,081 | H41 | inferred 0.80 | | Miami Beach, FL | 2014 |
| HELEN KELLER EYE RESEARCH FOUNDATION INC | $22,488 | H41 | published | science: research education | Birmingham, AL | 2024 |
| INTERNATIONAL THYROID EYE DISEASE SOCIETY INC | $21,209 | H41 | published | science: research education | Columbus, OH | 2025 |
| BLAYDES EYE FOUNDATION | $20,835 | H41 | published | | Bluefield, WV | 2024 |
| ANCHORAGE YORK RITE FOUNDATION INC | $20,475 | H41 | published | | Anchorage, AK | 2025 |
| INTERNATIONAL FOUNDATION FOR OPTIC NERVE DISEASE INC | $20,351 | H41 | published | | Cornwall, NY | 2025 |
| WRIGHT FOUNDATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS | $19,723 | H41 | published | | Torrance, CA | 2025 |
| INTERNATIONAL SOCIETY FOR GENETIC EYE DISEASE | $16,868 | H41 | published | | Pepper Pike, OH | 2024 |
| INTERNATIONAL ACADEMY OF ORTHOKERATOLOGY & MYOPIA CONTROL | $11,013 | H41 | published | | Jamul, CA | 2024 |
| WESTFIELD LIONS 100 FOUNDATION INC | $10,691 | H41 | published | | Longmeadow, MA | 2022 |
| EYE RESEARCH FOUNDATION OF SAN DIEGO | $10,000 | H41 | published | | La Jolla, CA | 2024 |
| GLAUCOMA SCIENCE AND EDUCATION FOUNDATION INC | $8,156 | H41 | published | science: research education | Great Neck, NY | 2025 |
| RETINA RESEARCH FOUNDATION OF AMERICA | $7,540 | H41 | published | | Scottsdale, AZ | 2025 |
| NEUROLOGICAL HEALTH INTERNATIONAL | $5,823 | H41 | published | | Santa Barbara, CA | 2024 |
| MADISON CENTRAL LIONS FOUNDATION INC | $4,940 | H41 | published | | Fitchburg, WI | 2024 |
| CURE AMD FOUNDATION | $4,454 | H41 | published | science: research education | Boulder, CO | 2024 |
| THE BETTER VISION FOUNDATION | $4,275 | H41 | published | | Chicago, IL | 2021 |
| ARIMAN & GENEAD FOUNDATION | $1,810 | H41 | published | | Newton Center, MA | 2024 |
| AGAWAM LIONS FOUNDATION INC | $1,096 | H41 | published | | Agawam, MA | 2024 |
| THE EYE INSTITUTE OF NEW JERSEY | $707 | H41 | inferred 0.60 | | New Brunswick, NJ | 2011 |
| MOORE EYE FOUNDATION | $272 | H41 | published | | Springfield, PA | 2015 |
| Glaucoma Research and Education | $46 | H41 | inferred 0.80 | | Indianapolis, IN | 2011 |
| GLAUCOMA RESEARCH AND EDUCATION FOUNDATION INC | $6 | H41 | published | | Fayetteville, NY | 2025 |
| COLLABORATIVE NETWORK OF INNOVATIVE VITREORETINAL SPECIALISTS | $4 | H41 | published | science: research education | Bloomfld Hls, MI | 2024 |
| JO HOYT FREEMAN EDUCATION FUND | $3 | H41 | inferred 0.80 | | Des Moines, IA | 2020 |