| AMERICAN HEART ASSOCIATION INC | $1,070,192,712 | G43 | published | survivor: cancer | Dallas, TX | 2024 |
| LIFESPAN PHYSICIAN GROUP INC | $366,760,724 | G43 | published | abuse: substance | Providence, RI | 2024 |
| AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION | $125,831,256 | G43 | published | science: research education | Washington, DC | 2024 |
| AMERICAN SOCIETY OF HEMATOLOGY INC | $112,402,449 | G43 | published | science: research education | Washington, DC | 2024 |
| THE HEART GROUP OF LANCASTER GENERAL HEALTH | $20,284,165 | G43 | published | science: research education | Lancaster, PA | 2024 |
| TEXAS HEART MEDICAL GROUP | $19,679,102 | G43 | published | science: research education | Houston, TX | 2024 |
| COPD FOUNDATION INC | $14,381,344 | G43 | published | launch: launch | Coral Gables, FL | 2024 |
| THE SOCIETY FOR CARIOVASCULAR ANGIOGRAPHY AND INTERVENTIONS | $12,943,367 | G43 | inferred 0.60 | science: research education | Washington, DC | 2024 |
| PULMONARY HYPERTENSION ASSOCIATION INC | $8,460,561 | G43 | published | science: research education | Washington, DC | 2024 |
| HEARTGIFT FOUNDATION | $6,057,751 | G43 | published | launch: religious | Austin, TX | 2025 |
| PIEDMONT HEART INSTITUTE INC | $5,488,913 | G43 | published | | Atlanta, GA | 2024 |
| ASSOCIATION OF BLACK CARDIOLOGISTS | $4,868,746 | G43 | published | | Washington, DC | 2024 |
| THE BRETT BOYER FOUNDATION INC | $4,820,916 | G43 | published | | Nashville, TN | 2024 |
| AMERICAN SOCIETY OF NUCLEAR CARDIOLOGY | $4,586,495 | G43 | published | science: research education | Fairfax, VA | 2024 |
| AHF SCHOOL OF ULTRASOUND INC | $3,790,953 | G43 | published | | Phoenix, AZ | 2025 |
| ASES FOUNDATION | $3,725,965 | G43 | inferred 0.50 | science: research education | Schaumburg, IL | 2025 |
| ALZHEIMER'S DISEASE & RELATED DISORDERS | $3,678,326 | G43 | inferred 0.55 | | Phoenix, AZ | 2015 |
| WHO WE PLAY FOR INC | $3,598,918 | G43 | published | | Melbourne, FL | 2024 |
| ANGIOGENESIS FOUNDATION INC | $3,105,155 | G43 | published | | Cambridge, MA | 2024 |
| THE THORACIC SURGERY FOUNDATION | $3,052,190 | G43 | inferred 0.60 | science: research education | Chicago, IL | 2024 |
| THE MENDED HEARTS INC | $2,160,865 | G43 | inferred 0.60 | | Leesburg, GA | 2025 |
| HYPERTROPHIC CARDIOMYOPATHY ASSOCIATION | $1,958,440 | G43 | published | science: research education | Denville, NJ | 2024 |
| PAKISTAN CHILDRENS HEART FOUNDATION NORTH AMERICA INC | $1,879,468 | G43 | published | launch: religious | Scarsdale, NY | 2024 |
| ADULT CONGENITAL HEART ASSOCIATION INC | $1,858,947 | G43 | published | science: research education | Columbia, MD | 2025 |
| AMERICAN SOCIETY FOR PREVENTIVE CARDIOLOGY | $1,623,329 | G43 | published | | Jacksonville, FL | 2022 |
| FOUNDATION FOR WOMEN AND GIRLS WITH BLOOD DISORDERS | $1,433,917 | G43 | published | girls boys: girls | Montclair, NJ | 2024 |
| SOCIETY FOR VASCULAR MEDICINE | $1,432,247 | G43 | published | science: research education | East Dundee, IL | 2024 |
| HEARTBRIGHT FOUNDATION | $1,303,580 | G43 | published | | Charlotte, NC | 2024 |
| SOCIETY FOR VASCULAR SURGERY FOUNDATION | $1,292,217 | G43 | published | science: research education | Rosemont, IL | 2024 |
| HEMOPHILIA OF INDIANA INC | $1,234,418 | G43 | inferred 0.50 | | Indianapolis, IN | 2024 |
| JOHN RITTER FOUNDATION FOR AORTIC HEALTH | $1,166,138 | G43 | published | science: research education | Los Angeles, CA | 2024 |
| THE GLOBAL HEART EDUCATION AND | $1,157,658 | G43 | inferred 0.50 | | New Orleans, LA | 2020 |
| STROKE COMEBACK CENTER | $1,122,300 | G43 | published | | Vienna, VA | 2025 |
| BLACK HEART ASSOCIATION | $1,122,095 | G43 | published | | Grand Prairie, TX | 2025 |
| CHILDRENS CARDIOMYOPATHY FOUNDATION INC | $996,165 | G43 | published | | Tenafly, NJ | 2025 |
| INTERNATIONAL SOCIETY FOR THE STUDY OF VASCULAR ANOMALIES | $875,060 | G43 | published | science: research education | Milwaukee, WI | 2024 |
| INTERNATIONAL CARDIAC ALLIANCE INC | $874,106 | G43 | published | | Burlington, VT | 2024 |
| MIGHTY OAKES HEART FOUNDATION | $805,107 | G43 | published | | Saint Louis, MO | 2025 |
| HETEROTAXY CONNECTION | $803,670 | G43 | published | science: research education | Eagle Mtn, UT | 2024 |
| PITUITARY SOCIETY INCORPORATED | $753,709 | G43 | published | science: research education | Los Angeles, CA | 2024 |
| AMERICAN JOURNAL OF HYPERTENSION LTD | $648,548 | G43 | published | science: research education | New York, NY | 2024 |
| NATIONAL KIDNEY FOUNDATION | $621,798 | G43 | inferred 0.60 | | New Orleans, LA | 2024 |
| HEART BROTHERS FOUNDATION INC | $610,079 | G43 | published | | Northborough, MA | 2024 |
| US THROMBOTIC MICROANGIOPATHY ALLIANCE | $595,494 | G43 | published | | Groveport, OH | 2024 |
| MAKE THEM KNOW YOUR NAME FOUNDATION | $582,768 | G43 | published | | Cleveland, OH | 2024 |
| INTERNATIONAL ATHEROSCLEROSIS SOCIETY | $569,686 | G43 | published | science: research education | Washington, DC | 2024 |
| CENTER FOR VASCULAR AWARENESS INC | $563,995 | G43 | published | science: research education | Latham, NY | 2024 |
| JOASH MEDICAL FOUNDATION | $548,900 | G43 | published | | Los Angeles, CA | 2024 |
| NORTH CAROLINA CHAPTER OF THE AMERICAN COLLEGE OF CARDIOLOGY | $548,859 | G43 | inferred 0.50 | | Raleigh, NC | 2025 |
| CHILDRENS HEART FOUNDATION | $540,388 | G43 | published | | Henderson, NV | 2025 |
| NATIONAL FORUM FOR HEART DISEASE | $528,898 | G43 | published | | Washington, DC | 2024 |
| NATIONAL ALLIANCE OF SICKLE CELL CENTERS | $527,453 | G43 | inferred 0.50 | | Washington, DC | 2024 |
| NORTH AMERICAN SOCIETY FOR CARDIAC IMAGING | $503,069 | G43 | published | | East Dundee, IL | 2025 |
| GOOD SAMARITAN INSTITUTE FOR RESEARCH AND EDUCATION | $500,227 | G43 | published | | Los Angeles, CA | 2024 |
| TEXAS SOCIETY OF PLASTIC SURGEONS | $493,872 | G43 | published | | Austin, TX | 2025 |
| PAMC HEALTH FOUNDATION INC | $483,135 | G43 | inferred 0.55 | abuse: substance | Los Angeles, CA | 2024 |
| SOUTHERN ASSOC FOR VASCULAR SURGERY INC | $482,296 | G43 | published | science: research education | Birmingham, AL | 2025 |
| SAN DIEGO HEART FAILURE FOUNDATION INC | $442,649 | G43 | published | | San Diego, CA | 2024 |
| TEXAS CENTRAL HEMOPHILIA ASSOC INC | $418,355 | G43 | published | men: issues | Dallas, TX | 2025 |
| MIDWESTERN VASCULAR SURGICAL SOCIETY | $418,065 | G43 | published | science: research education | Salem, MA | 2024 |
| TAMPA BAY HEART FOUNDATION INC | $408,515 | G43 | inferred 0.50 | science: research education | St Petersburg, FL | 2010 |
| SEATTLE CHILDRENS HOSPITAL | $406,991 | G43 | inferred 0.50 | | Seattle, WA | 2024 |
| LIVING HEART FOUNDATION INC | $391,185 | G43 | published | | Little Silver, NJ | 2025 |
| INTERNATIONAL SOCIETY FOR HEART RESEARCH INC | $381,461 | G43 | published | science: research education | Durham, NC | 2025 |
| BREAST CANCER SOLUTIONS | $355,808 | G43 | published | | Lake Forest, CA | 2025 |
| STROKE AWARENESS FOUNDATION | $337,123 | G43 | published | | Campbell, CA | 2025 |
| PARENT HEART WATCH | $336,780 | G43 | published | | Orlando, FL | 2024 |
| CARDIAC NEURODEVELOPMENTAL OUTCOME COLLABORATIVE | $319,183 | G43 | published | | Richmond, VA | 2025 |
| MCORE FOUNDATION | $317,710 | G43 | published | | Powell, OH | 2024 |
| PARALYZED VETERANS OF AMERICA SOUTHEASTERN CHAPTER INC | $305,110 | G43 | inferred 0.50 | | Hephzibah, GA | 2024 |
| INTERNATIONAL CONSORTIUM OFCIRCULATORY ASSIST CLINICIANS A NJ | $279,668 | G43 | published | | Del Mar, CA | 2025 |
| ARIZONA BLOOD ALLIANCE | $269,256 | G43 | published | | Phoenix, AZ | 2025 |
| NEW YORK CARDIOTHORACIC TRANSPLANT CONSORTIUM INC | $251,240 | G43 | published | | Troy, NY | 2025 |
| SAVE THE HEARTBEAT | $250,747 | G43 | published | | Glendora, CA | 2022 |
| GLOBAL ACTION NETWORK FOR SICKLE CELL & OTHER INHERITED BLOOD DISOR | $250,000 | G43 | published | | Dover, DE | 2025 |
| LOEYS-DIETZ SYNDROME FOUNDATION INC | $244,111 | G43 | inferred 0.60 | | Baltimore, MD | 2017 |
| PENNSYLVANIA CHAPTER OF THE AMERICAN COLLEGE CARDIOLOGY | $240,332 | G43 | inferred 0.80 | science: research education | West Chester, PA | 2025 |
| ROYAL ARCH MASONS CHILDRENS HEART FOUNDATION INC | $235,232 | G43 | published | | Marysville, WA | 2024 |
| HEALTHY HEARTS PLUS II INC | $233,136 | G43 | published | | N Chesterfld, VA | 2024 |
| ACADEMY OF CARDIOVASCULAR SCIENCES FOUNDATION USA INC | $232,259 | G43 | published | science: research education | Montclair, CA | 2025 |
| HEART DISEASE PREVENTION AND TRAINING CENTRE INC | $223,885 | G43 | published | | Ellicott City, MD | 2025 |
| GLOBAL HEART CARE INC | $223,601 | G43 | published | | Gold River, CA | 2024 |
| EINAR KIRKEGAARD TR FBO AM HEART ASSN | $210,444 | G43 | published | | Dallas, TX | 2024 |
| LANCASTER HEART ASSOCIATION TRUST 47FO52014 | $208,161 | G43 | inferred 0.60 | | Lancaster, PA | 2025 |
| FLORIDA VASCULAR FOUNDATION INC | $205,352 | G43 | published | | Jacksonville, FL | 2025 |
| SOCIETY FOR MAGNETIC RESONANCE ANGIOGRAPHY | $203,877 | G43 | published | science: research education | Madison, WI | 2025 |
| KARI S HEART FOUNDATION INC | $201,658 | G43 | published | | Johnson City, TN | 2024 |
| THE RACHEL COOPER FOUNDATION INC | $198,937 | G43 | inferred 0.60 | | Rego Park, NY | 2024 |
| NEW ENGLAND VALVE AND STRUCTURAL HEART FOUNDATION INC | $193,830 | G43 | published | | Dover, MA | 2023 |
| IN A HEARTBEAT INC | $193,391 | G43 | published | | Wallingford, CT | 2024 |
| HEALTHY HEART NATION | $188,968 | G43 | published | | Corona, CA | 2024 |
| CHIP MILLER CHARITABLE FOUNDATION | $182,848 | G43 | published | science: research education | Carlisle, PA | 2024 |
| INTERNATIONAL INSTITUTE FOR VASCULAR EDUCATION INC | $173,112 | G43 | published | | Brooklyn, NY | 2018 |
| INTERNATIONAL EOSINOPHIL SOCIETY INC | $166,844 | G43 | published | science: research education | Milwaukee, WI | 2024 |
| INTERAMERICAN HEART FOUNDATION INC | $166,630 | G43 | published | | Dallas, TX | 2024 |
| COMMUNITY HEALTH EDUCATION FOUNDATION | $164,796 | G43 | published | | Jonesboro, AR | 2025 |
| HEART HEALERS INTERNATIONAL | $164,514 | G43 | published | | New Orleans, LA | 2025 |
| PPCM FUND INC | $158,962 | G43 | published | | Heber City, UT | 2022 |
| GRAVES DISEASE AND THYROID FOUNDATION INC | $157,673 | G43 | inferred 0.50 | | Rcho Santa Fe, CA | 2025 |
| KENTUCKY AND SOUTHERN INDIANA STROKE ASSOCIATION INC | $153,842 | G43 | published | | Louisville, KY | 2025 |