| FRED HUTCHINSON CANCER RESEARCH CENTER | $696,845,474 | G30 | inferred 0.85 | survivor: cancer | Seattle, WA | 2021 |
| CENTRAL ARKANSAS RADIATION THERAPY INSTITUTE INC | $620,523,795 | G30 | published | survivor: cancer | Little Rock, AR | 2024 |
| BARBARA ANN KARMANOS CANCER HOSPITAL | $606,826,459 | G30 | published | science: research education | Detroit, MI | 2024 |
| BLOOD CANCER UNITED INC | $358,698,504 | G30 | published | survivor: cancer | Washington, DC | 2024 |
| MARY BIRD PERKINS CANCER CENTER | $318,045,658 | G30 | published | survivor: cancer | Baton Rouge, LA | 2024 |
| H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INC | $173,244,422 | G30 | published | science: research education | Tampa, FL | 2024 |
| AMERICAN CANCER SOCIETY INC | $136,826,348 | G30 | published | survivor: cancer | Atlanta, GA | 2024 |
| CANADIAN CANCER SOCIETY | $134,749,308 | G30 | published | survivor: cancer | Canada | 2024 |
| MIAMI CANCER INSTITUTE AT BAPTIST HEALTH INC | $132,288,902 | G30 | published | survivor: cancer | Coral Gables, FL | 2024 |
| American Cancer Society Inc Eastern | $93,589,588 | G30 | inferred 0.85 | survivor: cancer | White Plains, NY | 2010 |
| AMERICAN CANCER SOCIETY INC HIGH PLAINS | $92,872,717 | G30 | inferred 0.90 | survivor: cancer | Austin, TX | 2011 |
| SIOUXLAND REGIONAL CANCER CENTER | $78,004,916 | G30 | published | | Sioux City, IA | 2024 |
| TRENTON MEDICAL CENTER INC | $77,329,879 | G30 | published | | High Springs, FL | 2024 |
| American Cancer Society Inc Great West | $74,151,554 | G30 | inferred 0.80 | survivor: cancer | Seattle, WA | 2011 |
| AMERICAN CANCER SOCIETY INC MID-SOUTH | $64,151,507 | G30 | inferred 0.90 | survivor: cancer | Birmingham, AL | 2011 |
| AMERICAN CANCER SOCIETY INC NEW ENGLAND | $58,725,035 | G30 | inferred 0.80 | survivor: cancer | Framingham, MA | 2011 |
| American Cancer Society Inc Midwest Division | $54,430,964 | G30 | inferred 0.75 | survivor: cancer | Waukesha, WI | 2011 |
| AURORA INTEGRATED ONCOLOGY FOUNDATION | $53,740,844 | G30 | published | | Joelton, TN | 2024 |
| THE MARK FOUNDATION FOR CANCER RESEARCH US LTD | $44,772,901 | G30 | published | science: research education | New York, NY | 2024 |
| AMERICAN ASSOCIATION FOR CANCER RESEARCH FOUNDATION | $44,069,852 | G30 | published | science: research education | Philadelphia, PA | 2025 |
| ALEXS LEMONADE STAND FOUNDATION | $32,698,858 | G30 | inferred 0.80 | science: research education | Wynnewood, PA | 2025 |
| FRONTIER SCIENCE AND TECHNOLOGY RESEARCH FOUNDATION INC | $30,261,746 | G30 | published | science: research education | Amherst, NY | 2024 |
| WEST MICHIGAN CANCER CENTER | $25,736,169 | G30 | published | | Kalamazoo, MI | 2024 |
| CANCER CARE INC | $21,984,382 | G30 | published | | New York, NY | 2024 |
| CAROL MILGARD BREAST CENTER | $20,116,351 | G30 | published | girls boys: girl scouts | Tacoma, WA | 2024 |
| IMRAN KHAN CANCER APPEAL INC | $18,443,221 | G30 | inferred 0.50 | | Farmington, CT | 2024 |
| BISMARCK CANCER CENTER | $17,220,233 | G30 | published | survivor: cancer | Bismarck, ND | 2024 |
| SAINT JOHN S CANCER INSTITUTE | $16,797,010 | G30 | published | science: research education | Seattle, WA | 2024 |
| GUARDIAN RESEARCH NETWORK INC | $16,088,992 | G30 | published | | Spartanburg, SC | 2024 |
| ASSOCIATION OF COMMUNITY CANCER CENTERS | $15,625,626 | G30 | published | | Rockville, MD | 2024 |
| NATIONAL BRAIN TUMOR SOCIETY INC | $15,062,192 | G30 | inferred 0.70 | survivor: cancer | Newton, MA | 2025 |
| UNION FOR INTERNATIONAL CANCER CONTROL | $14,460,182 | G30 | published | survivor: cancer | Switzerland | 2024 |
| UT SOUTHWESTERN MONCRIEF CANCER CENTER | $14,176,226 | G30 | published | survivor: cancer | Fort Worth, TX | 2024 |
| CANCER FOUNDATION OF SANTA BARBARA | $12,010,526 | G30 | published | | Santa Barbara, CA | 2024 |
| ALLIANCE NCTN FOUNDATION | $10,906,644 | G30 | published | | Chicago, IL | 2024 |
| SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE | $8,921,973 | G30 | published | survivor: cancer | San Diego, CA | 2024 |
| RONALD MCDONALD HOUSE CHARITIES UPPER MIDWEST | $8,068,283 | G30 | published | science: research education | Minneapolis, MN | 2024 |
| CANCER SUPPORT COMMUNITY SAN FRANCISCO BAY AREA | $7,925,449 | G30 | published | | Walnut Creek, CA | 2025 |
| Arthritis Foundation Pacific Region Inc | $7,789,290 | G30 | inferred 0.60 | science: research education | Los Angeles, CA | 2015 |
| CINCINNATI CANCER FOUNDATION INC | $7,507,151 | G30 | published | survivor: cancer | Cincinnati, OH | 2025 |
| RONALD MCDONALD HOUSE SOUTHERN ARIZONA | $7,495,683 | G30 | published | | Tucson, AZ | 2025 |
| HEALTHTREE FOUNDATION INC | $7,483,147 | G30 | published | | South Jordan, UT | 2024 |
| RONALD MCDONALD HOUSE CHARITIES OF DENVER INC | $6,862,391 | G30 | published | girls boys: girls | Denver, CO | 2025 |
| AMERICAN LUNG ASSOC OF THE MOUNTAIN PACIFIC | $6,717,008 | G30 | published | survivor: cancer | Seattle, WA | 2016 |
| HEMATOLOGY ONCOLOGY PHARMACY ASSOCIATION INC | $6,714,837 | G30 | published | science: research education | Milwaukee, WI | 2024 |
| NASHUA REGIONAL CANCER CENTER INC | $6,220,505 | G30 | published | | Nashua, NH | 2025 |
| COMMUNITY CANCER FOUNDATION COMMUNITY CANCER CENTER | $5,913,708 | G30 | published | survivor: cancer | Roseburg, OR | 2024 |
| RONALD MCDONALD HOUSE WEST TENNESSEE & NORTHEAST ARKANSAS | $5,450,335 | G30 | published | | Memphis, TN | 2024 |
| SAN ANTONIO CANCER FOUNDATION | $4,955,768 | G30 | inferred 0.80 | science: research education | San Antonio, TX | 2016 |
| JAIME LEANDRO FOUNDATION FOR THERAPEUTIC CANCER VACCINES | $4,828,327 | G30 | published | | Chapel Hill, NC | 2025 |
| CANCER CENTER OF WESTERN WISCONSIN INC | $4,775,430 | G30 | published | survivor: cancer | New Richmond, WI | 2024 |
| LIGA CONTRA EL CANCER INC LEAGUE AGAINST CANCER INC | $4,737,649 | G30 | published | | Miami, FL | 2025 |
| FAYETTE ONCOLOGY ASSOCIATES | $4,626,648 | G30 | published | science: research education | Pittsburgh, PA | 2024 |
| WELLNESS HOUSE | $4,611,105 | G30 | published | | Hinsdale, IL | 2024 |
| MIDWEST ATHLETES AGAINST CHILDHOOD CANCER INC | $4,563,453 | G30 | published | | Milwaukee, WI | 2024 |
| ROC SOLID FOUNDATION INC | $4,507,115 | G30 | published | | Chesapeake, VA | 2025 |
| Arthritis Foundation Florida Chapter Inc | $4,310,331 | G30 | inferred 0.80 | science: research education | Atlanta, GA | 2014 |
| INTERNATIONAL LUNG CANCER FOUNDATION | $4,273,165 | G30 | inferred 0.75 | | Denver, CO | 2022 |
| CANCER FOR COLLEGE | $4,202,859 | G30 | published | survivor: cancer | San Diego, CA | 2024 |
| PROMISE FUND OF FLORIDA INC | $4,189,322 | G30 | published | survivor: cancer | West Palm Beach, FL | 2024 |
| ACS PRODUCTS INC | $4,115,610 | G30 | inferred 0.60 | women: issues | Kennesaw, GA | 2020 |
| RONALD MCDONALD HOUSE LEXINGTON INC | $4,040,814 | G30 | published | | Lexington, KY | 2025 |
| UPMC-ST CLAIR HOSPITAL CANCER CENTER | $3,847,898 | G30 | published | science: research education | Pittsburgh, PA | 2024 |
| PERSONAL CARE PRODUCTS COUNCIL FOUNDATION | $3,844,040 | G30 | published | men: issues | Washington, DC | 2024 |
| ALK POSITIVE INCORPORATED | $3,836,237 | G30 | inferred 0.70 | | Atlanta, GA | 2025 |
| FLORIDA SOCIETY OF CLINICAL ONCOLOGY INC | $3,795,093 | G30 | published | science: research education | Riverview, FL | 2024 |
| JOE ANDRUZZI FOUNDATION INC | $3,741,896 | G30 | published | | North Attleboro, MA | 2024 |
| BREAST CANCER PREVENTION PARTNERS | $3,694,152 | G30 | published | science: research education | San Francisco, CA | 2024 |
| ULMAN FOUNDATION INC | $3,691,650 | G30 | published | survivor: cancer | Baltimore, MD | 2024 |
| NATIONAL CANCER CENTER INC | $3,605,404 | G30 | published | science: research education | West Islip, NY | 2024 |
| Lung Cancer Alliance | $3,595,300 | G30 | inferred 0.80 | survivor: cancer | Washington, DC | 2019 |
| ANGEL FOUNDATION | $3,460,565 | G30 | published | survivor: cancer | Mendota Hts, MN | 2025 |
| CANDLELIGHTERS FOR CHILDHOOD CANCER | $3,431,426 | G30 | published | survivor: cancer | Las Vegas, NV | 2025 |
| ONCOLOGY NURSING FOUNDATION | $3,426,421 | G30 | published | science: research education | Pittsburgh, PA | 2025 |
| FIGHT COLORECTAL CANCER INC | $3,357,068 | G30 | published | survivor: cancer | Springfield, MO | 2024 |
| VITAL ACCESS CARE FOUNDATION | $3,252,848 | G30 | published | survivor: cancer | Fountain Vly, CA | 2024 |
| CANCER CARE SERVICES | $3,208,328 | G30 | published | survivor: cancer | Fort Worth, TX | 2024 |
| CANCER INSTITUTE OF NEW JERSEY FOUNDATION | $3,196,512 | G30 | inferred 0.50 | science: research education | New Brunswick, NJ | 2012 |
| EARL AND BESSIE WHEDON CANCER DETECTION FOUNDATION | $3,119,080 | G30 | inferred 0.60 | | Sheridan, WY | 2025 |
| LANCE ARMSTRONG FOUNDATION EVENTS | $3,115,134 | G30 | inferred 0.60 | survivor: cancer | Austin, TX | 2010 |
| ASSOCIATION OF AMERICAN CANCER INSTITUTES | $3,077,699 | G30 | published | | Pittsburgh, PA | 2025 |
| CANCER CARE CNTR OF YORK COUNTY | $3,005,405 | G30 | inferred 0.70 | | Portland, ME | 2017 |
| BUTLER CANCER ASSOCIATES INC | $2,990,000 | G30 | published | science: research education | Pittsburgh, PA | 2024 |
| CANCER CANT | $2,957,241 | G30 | published | | Spokane, WA | 2024 |
| UNITING AGAINST LUNG CANCER | $2,947,847 | G30 | inferred 0.85 | science: research education | New York, NY | 2014 |
| SOUTHEAST CLINICAL ONCOLOGY RESEARCH CONSORTIUM INC | $2,889,887 | G30 | published | | Winston Salem, NC | 2024 |
| NORTHERN ILLINOIS CANCER TREATMENT CENTER | $2,878,651 | G30 | published | | Dixon, IL | 2024 |
| NEVADA CHILDHOOD CANCER FOUNDATION | $2,728,331 | G30 | published | | Las Vegas, NV | 2024 |
| FUNDACION CAP INC | $2,720,761 | G30 | published | | San Juan, PR | 2025 |
| AIM AT MELANOMA | $2,671,461 | G30 | published | survivor: cancer | Sacramento, CA | 2025 |
| FORCE-FACING OUR RISK OF CANCER EMPOWERED | $2,642,483 | G30 | published | survivor: cancer | Tampa, FL | 2025 |
| ASSOCIATION OF PEDIATRIC HEMATOLOGY ONCOLOGY NURSES INC | $2,640,422 | G30 | published | science: research education | Mclean, VA | 2024 |
| CANCER WELLNESS CENTER | $2,620,283 | G30 | published | | Northbrook, IL | 2025 |
| YOUNG SURVIVAL COALITION INC | $2,572,150 | G30 | published | survivor: cancer | New York, NY | 2024 |
| T O U C H THERAPY INC | $2,563,215 | G30 | published | survivor: cancer | Annapolis, MD | 2024 |
| TEXAS RESEARCH AND TECHNOLOGY FOUNDATION | $2,532,193 | G30 | published | science: research education | San Antonio, TX | 2024 |
| IMERMAN ANGELS | $2,420,333 | G30 | published | survivor: cancer | Chicago, IL | 2024 |
| AMERICAN INDIAN CANCER FOUNDATION | $2,388,645 | G30 | published | survivor: cancer | Minneapolis, MN | 2024 |
| JULIE ROGERS GIFT OF LIFE FREE MAMMOGRAM PROGRAM | $2,355,655 | G30 | published | survivor: cancer | Beaumont, TX | 2024 |
| COLON CANCER COALITION FOUNDATION | $2,317,522 | G30 | published | survivor: cancer | Minneapolis, MN | 2025 |