| NEW YORK HOTEL TRADES COUNCIL AND HOTEL ASSOC OF NYC INC HEALTH BENE | $562,005,789 | E86 | inferred 0.60 | | New York, NY | 2024 |
| BloodSource Inc | $138,943,323 | E86 | inferred 0.60 | science: research education | Mather, CA | 2016 |
| RONALD MCDONALD HOUSE GLOBAL | $134,535,982 | E86 | published | | Chicago, IL | 2025 |
| CARE DESIGN NEW YORK LLC | $131,542,178 | E86 | published | | Albany, NY | 2024 |
| SEMPER FI & AMERICAS FUND | $56,599,765 | E86 | published | | Quantico, VA | 2024 |
| ACHIEVE BEHAVIORAL HEALTH | $44,920,861 | E86 | published | | Airmont, NY | 2024 |
| FAMILY HOUSE INC | $43,668,323 | E86 | published | | San Francisco, CA | 2024 |
| CHAI LIFELINE INC | $32,830,835 | E86 | published | | New York, NY | 2024 |
| RONALD MCDONALD HOUSE ATLANTA INC | $30,046,456 | E86 | published | | Atlanta, GA | 2024 |
| ASHLEY HOUSE | $27,040,533 | E86 | published | | Federal Way, WA | 2025 |
| EXCEPTIONAL FAMILY RESOURCES INC | $26,491,272 | E86 | published | | Syracuse, NY | 2024 |
| CHILDRENS INN AT NIH INC | $26,460,643 | E86 | published | science: research education | Bethesda, MD | 2024 |
| LUTHERAN SENIOR SERVICES ENDOWMENT FUND | $25,252,843 | E86 | inferred 0.45 | | St Louis, MO | 2024 |
| MAKE-A-WISH FOUNDATION OF OHIO KENTUCKY AND INDIANA INC | $18,472,500 | E86 | published | | Columbus, OH | 2024 |
| MAKE A WISH FOUNDATION OF SOUTHERN FLORIDA INC | $18,330,545 | E86 | published | | Miami, FL | 2024 |
| RONALD MCDONALD HOUSE ARKANSAS & NORTH LOUISIANA INC | $17,655,738 | E86 | published | science: research education | Little Rock, AR | 2025 |
| RONALD MCDONALD HOUSE OF NEW YORK INC | $17,230,849 | E86 | published | science: research education | New York, NY | 2024 |
| FRIENDS OF CHILDREN WITH SPECIAL NEEDS | $12,956,694 | E86 | published | | Fremont, CA | 2024 |
| CHILDRENS HARBOR INC | $12,341,995 | E86 | published | | Eclectic, AL | 2025 |
| BELIEVE IN TOMORROW NATIONAL CHILDRENS FOUNDATION INC | $12,293,766 | E86 | published | | Baltimore, MD | 2025 |
| MAKE-A-WISH FOUNDATION OF MICHIGAN | $12,078,474 | E86 | published | | Southfield, MI | 2024 |
| RONALD MCDONALD HOUSE CHARLESTON | $12,065,208 | E86 | published | | Charleston, SC | 2025 |
| MAKE-A-WISH FOUNDATION OF THE TEXAS GULF COAST AND LOUISIANA INC | $10,936,356 | E86 | published | | Stafford, TX | 2024 |
| MAKE A WISH FOUNDATION OF ARIZONA INC | $10,844,064 | E86 | published | | Scottsdale, AZ | 2024 |
| RONALD MCDONALD HOUSE TAMPA BAY INC | $10,829,723 | E86 | published | | Tampa, FL | 2025 |
| THE HOSPITAL COTTAGES FOR CHILDREN | $10,592,865 | E86 | published | | Southborough, MA | 2024 |
| MAKE A WISH FOUNDATION OF NEW JERSEY | $9,715,285 | E86 | published | | Monroe Township, NJ | 2024 |
| MAKE A WISH FOUNDATION OF PHILADELPHIA DELWARE & SUS VALLEY | $9,640,425 | E86 | published | | Bala Cynwyd, PA | 2024 |
| MAKE-A-WISH FOUNDATION OF WISCONSIN INC | $9,629,579 | E86 | published | launch: religious | Wauwatosa, WI | 2024 |
| RONALD MCDONALD HOUSE KANSAS CITY | $9,547,150 | E86 | published | | Kansas City, MO | 2024 |
| RONALD MCDONALD HOUSE OREGON | $9,425,123 | E86 | published | | Portland, OR | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF NORTHEAST OHIO INC | $9,305,338 | E86 | published | women: issues | Cleveland, OH | 2024 |
| RONALD MCDONALD HOUSE CHARITIES GREATER HOUSTON INC | $9,202,612 | E86 | published | | Houston, TX | 2024 |
| HOPEKIDS INC | $8,933,405 | E86 | published | | Scottsdale, AZ | 2025 |
| MAKE-A-WISH FOUNDATION OF CENTRAL AND NORTHERN FLORIDA INC | $8,907,427 | E86 | published | | Maitland, FL | 2024 |
| MAKE-A-WISH FOUNDATION OF MASSACHUSETTS AND RHODE ISLAND INC | $8,873,775 | E86 | published | | Boston, MA | 2024 |
| RONALD MCDONALD HOUSE CHARITIES OF THE INTERMOUNTAIN AREA INC | $8,578,749 | E86 | published | | Salt Lake Cty, UT | 2025 |
| MAKE-A-WISH FOUNDATION OF ALASKA & WASHINGTON | $8,393,521 | E86 | published | | Seattle, WA | 2024 |
| MAKE-A-WISH FOUNDATION OF COLORADO INC | $8,365,781 | E86 | published | | Greenwood Vlg, CO | 2024 |
| TUBMAN CENTER FOR HEALTH & FREEDOM | $7,959,818 | E86 | published | violence: prevention | Seattle, WA | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF WESTERN WASHINGTON & ALASKA | $7,479,076 | E86 | published | | Seattle, WA | 2024 |
| RONALD MCDONALD HOUSE CHARITIES OF EASTERN WISCONSIN INC | $7,370,774 | E86 | published | | Wauwatosa, WI | 2025 |
| MAKE-A-WISH FOUNDATION OF CENTRAL AND WESTERN NORTH CAROLINA INC | $7,184,850 | E86 | published | | Waxhaw, NC | 2024 |
| THE BOGGY CREEK GANG INC | $7,168,889 | E86 | published | | Eustis, FL | 2024 |
| RESOURCE CONNECTIONS OF OREGON | $6,931,627 | E86 | published | | Salem, OR | 2024 |
| MAKE-A-WISH NORTHEASTERN & CENTRAL CALIFORNIA | $6,780,598 | E86 | published | | Sacramento, CA | 2024 |
| LIGHTHOUSE FAMILY RETREAT INC | $6,757,986 | E86 | published | | Alpharetta, GA | 2024 |
| RONALD MCDONALD HOUSE CHARITIES OF RICHMOND VA INC | $6,549,946 | E86 | published | survivor: cancer | Richmond, VA | 2024 |
| MAKE-A-WISH FOUNDATION OF CT INC | $6,460,196 | E86 | published | | Trumbull, CT | 2024 |
| RONALD MCDONALD HOUSE CENTRAL FLORIDA INC | $6,219,785 | E86 | published | | Orlando, FL | 2025 |
| MAKE-A-WISH FOUNDATION OF ORANGE COUNTY | $6,125,499 | E86 | published | | Irvine, CA | 2024 |
| HELP HOSPITALIZED VETERANS | $6,087,449 | E86 | published | abuse: substance | Winchester, CA | 2024 |
| CHESED OF LAKEWOOD | $6,061,937 | E86 | published | | Lakewood, NJ | 2024 |
| SOUTHERN REGIONAL RESOURCE CENTER | $6,061,705 | E86 | published | | Chula Vista, CA | 2024 |
| RONALD MCDONALD HOUSE LOUISVILLE INC | $6,035,391 | E86 | published | girls boys: boys girls clubs | Louisville, KY | 2025 |
| HOSPITAL HOSPITALITY HOUSE OF RICHMOND INC | $5,986,688 | E86 | published | | Richmond, VA | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF CENTRAL TEXAS INC | $5,819,048 | E86 | published | women: issues | Austin, TX | 2024 |
| JACOBS HEART CHILDRENS CANCER SUPPORT SERVICES | $5,735,777 | E86 | published | | Watsonville, CA | 2024 |
| HIGH FIVES NONPROFIT FOUNDATION | $5,698,251 | E86 | published | | Truckee, CA | 2024 |
| MAKE-A-WISH FOUNDATION OF THE MID- SOUTH INC | $5,408,189 | E86 | published | | Memphis, TN | 2024 |
| GROWTH OPPORTUNITY CENTER INC | $5,347,397 | E86 | published | | Southampton, PA | 2025 |
| PROJECT CAMP INC | $5,296,877 | E86 | published | | Scottsville, KY | 2025 |
| MAKE-A-WISH FOUNDATION OF SC INC | $5,143,365 | E86 | published | | Greenville, SC | 2024 |
| FAMILY HOUSE INC | $5,125,142 | E86 | published | | Pittsburgh, PA | 2024 |
| THE MS CENTER OF SAINT LOUIS | $5,068,793 | E86 | inferred 0.60 | | Chesterfield, MO | 2016 |
| RONALD MCDONALD HOUSE CHARITIES SOUTH TEXAS | $5,006,194 | E86 | published | | Corp Christi, TX | 2024 |
| MAKE A WISH FOUNDATION OF MISSISSIPPI CHARTERED | $4,792,440 | E86 | published | | Ridgeland, MS | 2024 |
| MAKE-A-WISH FOUNDATION OF HAWAII INC | $4,789,306 | E86 | published | | Honolulu, HI | 2024 |
| MAKE A WISH FOUNDATION OF OREGON INC | $4,705,224 | E86 | published | | Portland, OR | 2024 |
| MAKE-A-WISH FOUNDATION OF MAINE | $4,689,116 | E86 | published | | Scarborough, ME | 2024 |
| CHILDRENS ASSOCIATION FOR MAXIMUM POTENTIAL INC | $4,673,782 | E86 | published | | San Antonio, TX | 2025 |
| MAKE-A-WISH FOUNDATION OF MINNESOTA | $4,646,575 | E86 | published | | Saint Paul, MN | 2024 |
| VALLEY CAREGIVER RESOURCE CENTER | $4,637,275 | E86 | published | | Fresno, CA | 2024 |
| RONALD MCDONALD HOUSE OF SOUTHERN NEW JERSEY INC | $4,493,058 | E86 | published | | Camden, NJ | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF IDAHO INC | $4,467,521 | E86 | published | | Boise, ID | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF GREATER WASHINGTON DC INC | $4,360,611 | E86 | published | | Falls Church, VA | 2024 |
| SUNSHINE KIDS FOUNDATION | $4,313,330 | E86 | published | survivor: cancer | Houston, TX | 2025 |
| RONALD MCDONALD HOUSE ALBANY INC | $4,226,921 | E86 | published | abuse: child | Albany, NY | 2025 |
| CANARSIE AWARE INC | $4,175,984 | E86 | inferred 0.60 | abuse: substance | Brooklyn, NY | 2013 |
| DONATE LIFE FOUNDATION | $4,088,832 | E86 | published | science: research education | Saint Louis, MO | 2024 |
| NEW YORK CANCER CENTER INC | $4,083,306 | E86 | published | | Brooklyn, NY | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF ROCHESTER NY INC | $3,956,002 | E86 | published | abuse: sexual | Rochester, NY | 2025 |
| CLL SOCIETY INC | $3,944,332 | E86 | published | | Nashville, TN | 2024 |
| THE RAINBOW CONNECTION | $3,936,965 | E86 | published | | Rochester, MI | 2025 |
| SADDLE UP | $3,933,607 | E86 | published | | Franklin, TN | 2024 |
| RONALD MCDONALD HOUSE CHARITIES OF NASHVILLE TN INC | $3,920,142 | E86 | published | | Nashville, TN | 2025 |
| RONALD MCDONALD HOUSE JACKSONVILLE INC | $3,895,696 | E86 | published | science: research education | Jacksonville, FL | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF THE PIEDMONT TRIAD INC | $3,651,888 | E86 | published | | Winston Salem, NC | 2025 |
| CHILDS PLAY | $3,646,742 | E86 | published | domestic violence | Seattle, WA | 2025 |
| MAKE-A-WISH FOUNDATION OF IOWA INC | $3,619,375 | E86 | published | | Urbandale, IA | 2024 |
| QUANTUM HOUSE INC | $3,574,930 | E86 | published | | Mangonia Park, FL | 2025 |
| TRANSPLANT HOUSE | $3,565,138 | E86 | published | launch: launch | Philadelphia, PA | 2024 |
| RMHC CTMA | $3,440,568 | E86 | published | shelter: homeless | New Haven, CT | 2024 |
| RONALD MCDONALD HOUSE MADISON INC | $3,332,558 | E86 | published | | Madison, WI | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF GREATER CHATTANOOGA INC | $3,250,992 | E86 | published | | Chattanooga, TN | 2025 |
| PLUMBERS & STEAMFITTERS LOCAL 6 | $3,213,955 | E86 | inferred 0.60 | | Mendota Heights, MN | 2012 |
| DAVIDS HOUSE INC | $3,205,736 | E86 | published | | Lebanon, NH | 2024 |
| AUTISM SOCIETY OF MINNESOTA | $3,149,544 | E86 | published | women: issues | Saint Paul, MN | 2025 |
| MAKE A WISH FOUNDATION OF GREATER VIRGINIA | $3,146,364 | E86 | published | | Richmond, VA | 2024 |
| RONALD MCDONALD HOUSE CHARITIES NORTHERN NEVADA INC | $3,098,097 | E86 | published | women: issues | Reno, NV | 2025 |