| VITALANT | $739,592,382 | E61 | published | | Scottsdale, AZ | 2024 |
| NEW YORK BLOOD CENTER INC | $629,039,352 | E61 | published | science: research education | New York, NY | 2025 |
| ONEBLOOD INC | $450,740,907 | E61 | published | science: research education | Orlando, FL | 2024 |
| VERSITI BLOOD HEALTH INC | $281,020,247 | E61 | published | science: research education | Milwaukee, WI | 2024 |
| BLOODWORKS | $167,526,090 | E61 | published | science: research education | Seattle, WA | 2024 |
| CARTER BLOODCARE | $160,711,753 | E61 | published | | Bedford, TX | 2024 |
| OKLAHOMA BLOOD INSTITUTE | $155,925,006 | E61 | published | science: research education | Oklahoma City, OK | 2024 |
| LIFESOUTH COMMUNITY BLOOD CENTERS INC | $151,267,533 | E61 | published | science: research education | Gainesville, FL | 2024 |
| THE BLOOD CONNECTION INCORPORATED | $149,672,688 | E61 | published | | Piedmont, SC | 2024 |
| GULF COAST REGIONAL BLOOD CENTER | $132,655,313 | E61 | published | | Houston, TX | 2024 |
| QUALTEX LABORATORIES | $128,419,177 | E61 | published | | San Antonio, TX | 2024 |
| LIFEGIFT ORGAN DONATION CENTER | $104,117,543 | E61 | published | | Houston, TX | 2024 |
| BLOOD SYSTEMS INC | $98,154,806 | E61 | published | | Scottsdale, AZ | 2018 |
| VERSITI INDIANA INC | $93,681,273 | E61 | published | science: research education | Indianapolis, IN | 2024 |
| SOUTH TEXAS BLOOD & TISSUE CENTER | $84,915,807 | E61 | published | science: research education | San Antonio, TX | 2024 |
| VERSITI MICHIGAN INC | $74,790,441 | E61 | published | science: research education | Grand Rapids, MI | 2024 |
| BLOOD ASSURANCE INC | $72,291,189 | E61 | published | | Chattanooga, TN | 2025 |
| WE ARE BLOOD | $70,408,356 | E61 | published | | Austin, TX | 2024 |
| VERSITI ILLINOIS INC | $65,189,416 | E61 | published | science: research education | Aurora, IL | 2024 |
| INNOVATIVE BLOOD RESOURCES | $62,700,542 | E61 | inferred 0.93 | | St Paul, MN | 2018 |
| LIFESTREAM BLOOD BANK | $60,711,584 | E61 | published | science: research education | Sn Bernrdno, CA | 2024 |
| LIFESERVE BLOOD CENTER | $52,491,129 | E61 | published | | Johnston, IA | 2025 |
| BENEDICTINE LIVING COMMUNITIES INC | $46,054,279 | E61 | inferred 0.55 | | Minneapolis, MN | 2024 |
| KENTUCKY BLOOD CENTER INC | $37,863,561 | E61 | published | | Lexington, KY | 2024 |
| HCSC BLOOD CENTER | $32,313,692 | E61 | published | | Allentown, PA | 2024 |
| THE BLOOD CENTER | $30,535,789 | E61 | published | | New Orleans, LA | 2025 |
| BLOOD BANK OF HAWAII | $28,221,633 | E61 | inferred 0.85 | | Kapolei, HI | 2024 |
| MISSISSIPPI BLOOD SERVICES INC | $22,645,089 | E61 | published | launch: religious | Flowood, MS | 2025 |
| MEDIC INC | $22,622,816 | E61 | published | | Knoxville, TN | 2024 |
| COMMUNITY BLOOD CENTER OF THE OZARKS | $21,982,034 | E61 | published | | Springfield, MO | 2024 |
| COMMUNITY BLOOD CENTER INC | $21,910,650 | E61 | published | | Appleton, WI | 2024 |
| MID-SOUTH REGIONAL BLOOD CENTER INC | $21,657,785 | E61 | inferred 0.85 | science: research education | Memphis, TN | 2014 |
| AMERICAN ASSOCIATION OF BLOOD BANKS | $19,618,911 | E61 | published | science: research education | Bethesda, MD | 2024 |
| CENTRAL PENNSYLVANIA BLOOD BANK | $19,507,121 | E61 | published | | Hummelstown, PA | 2024 |
| HOUCHIN COMMUNITY BLOOD BANK | $18,629,457 | E61 | published | | Bakersfield, CA | 2025 |
| SUNCOAST COMMUNITIES BLOOD BANK INC | $17,855,156 | E61 | published | | Bradenton, FL | 2024 |
| COMMUNITY BLOOD CENTER OF THE CAROLINAS | $16,891,474 | E61 | inferred 0.85 | | Charlotte, NC | 2018 |
| CYPRESS GLEN RETIREMENT COMMUNITY | $15,243,049 | E61 | inferred 0.60 | | Durham, NC | 2012 |
| COASTAL BEND BLOOD CENTER | $13,314,734 | E61 | published | | Corp Christi, TX | 2024 |
| WALTER L SHEPEARD COMMUNITY BLOOD CENTER INC | $12,967,295 | E61 | inferred 0.90 | | Augusta, GA | 2024 |
| BLOOD BANK OF ALASKA INC | $12,811,827 | E61 | published | | Anchorage, AK | 2024 |
| CENTRAL CALIFORNIA BLOOD CENTER | $10,842,898 | E61 | published | | Fresno, CA | 2025 |
| NORTHERN ILLINOIS BLOOD BANK INC | $10,834,747 | E61 | published | | Rockford, IL | 2024 |
| WEST TENN REGIONAL BLOOD CENTER INC | $10,613,641 | E61 | inferred 0.90 | | Jackson, TN | 2025 |
| WILLIAMSPORT AREA AMBULANCE SERVICE COOPERATIVE | $10,383,568 | E61 | published | | Pittsburgh, PA | 2024 |
| COMMUNITY BLOOD BANK OF ERIE COUNTY | $8,083,041 | E61 | published | | Erie, PA | 2024 |
| AMERICAN ASSOCIATION OF TISSUE BANKS INC | $7,958,410 | E61 | inferred 0.55 | science: research education | Washington, DC | 2025 |
| LAMOILLE HOME HEALTH AGENCY INC | $7,822,217 | E61 | inferred 0.60 | | Morrisville, VT | 2024 |
| CARTER BLOODCARE FOUNDATION | $6,752,588 | E61 | inferred 0.75 | | Bedford, TX | 2024 |
| INDIANA LIONS EYE BANK INC | $6,615,495 | E61 | inferred 0.80 | | Carmel, IN | 2025 |
| NORTHERN CALIFORNIA COMMUNITY BLOOD BANK | $5,960,267 | E61 | inferred 0.90 | | Eureka, CA | 2024 |
| Regional Health Resource Center | $5,648,008 | E61 | inferred 0.90 | | Urbana, IL | 2010 |
| POCONO MOUNTAIN REGIONAL EMERGENCY MEDICAL SERVICES INC | $5,499,387 | E61 | published | | Tobyhanna, PA | 2025 |
| BBG ADVANCED THERAPIES | $5,427,037 | E61 | published | science: research education | San Antonio, TX | 2024 |
| VITALANT FOUNDATION | $3,758,335 | E61 | published | science: research education | Scottsdale, AZ | 2024 |
| WESTERN KENTUCKY REGIONAL BLOOD CENTER INC | $3,452,790 | E61 | published | | Owensboro, KY | 2024 |
| BROOKLYN UNITED METHODIST CONTINUUM SERVICES INC | $3,179,057 | E61 | published | | Brooklyn, NY | 2024 |
| PLATELET DISORDER SUPPORT ASSOCIATION INC | $2,970,096 | E61 | published | science: research education | Brecksville, OH | 2025 |
| SIOUXLAND COMMUNITY BLOOD BANK | $2,876,347 | E61 | inferred 0.85 | | Des Moines, IA | 2011 |
| TEXOMA REGIONAL BLOOD CENTER | $2,795,471 | E61 | published | | Sherman, TX | 2024 |
| INTERNATIONAL COUNCIL FOR COMMONALITY IN BLOOD BANKING AUTO | $2,469,721 | E61 | published | | Redlands, CA | 2024 |
| Community Blood Council of NJ Inc | $2,262,187 | E61 | inferred 0.85 | | Lawrenceville, NJ | 2017 |
| NIGHTINGALE HOME CARE INC | $2,227,382 | E61 | inferred 0.50 | | Columbus, OH | 2014 |
| EMBLEMHEALTH INC | $2,212,007 | E61 | inferred 0.55 | | New York, NY | 2024 |
| LIFESHARE FOUNDATION | $2,024,378 | E61 | inferred 0.60 | | Sheffield Village, OH | 2015 |
| AMERICAN DONOR SERVICES INC | $1,902,489 | E61 | published | | Cottage Grove, MN | 2025 |
| LIFESHARE BLOOD CENTERS FOUNDATION | $1,530,842 | E61 | published | | Shreveport, LA | 2025 |
| TACOMA-PIERCE COUNTY BLOOD BANK | $1,202,470 | E61 | published | | Tacoma, WA | 2024 |
| THE BLOOD & TISSUE CENTER FOUNDATION | $1,135,732 | E61 | published | science: research education | San Antonio, TX | 2024 |
| OKLAHOMA MOTHERS MILK BANK INC | $764,895 | E61 | published | | Oklahoma City, OK | 2024 |
| MEDICAL EYE BANK OF WEST VIRGINIA INC | $713,768 | E61 | inferred 0.75 | science: research education | Charleston, WV | 2024 |
| HAWAII CORD BLOOD BANK | $680,995 | E61 | published | | Honolulu, HI | 2024 |
| COFFEE MEMORIAL BLOOD CENTER FOUNDATION | $680,057 | E61 | published | | Amarillo, TX | 2024 |
| THE SOCIETY FOR THE ADVANCEMENT OF BLOOD MANAGEMENT | $651,219 | E61 | published | science: research education | Mount Royal, NJ | 2024 |
| ALLIANCE FOR COMMUNITY TRANSFUSION SERVICES LLC | $627,209 | E61 | published | | Bedford, TX | 2025 |
| DONATE LIFE FOUNDATION OF UPSTATE NEW | $473,638 | E61 | inferred 0.60 | | Buffalo, NY | 2012 |
| Breast Cancer Resource Center | $235,236 | E61 | inferred 0.55 | | Tacoma, WA | 2010 |
| GREENWOOD BAND PARENTS ORGANIZATION INC | $226,348 | E61 | published | | Greenwood, IN | 2025 |
| SOUTH CENTRAL ASSOCIATION OF BLOOD BANKS | $222,492 | E61 | published | | Lexington, KY | 2024 |
| MUSIC SAVES LIVES | $193,910 | E61 | published | | Seal Beach, CA | 2011 |
| ORCHARD MANOR INC | $193,227 | E61 | inferred 0.60 | | Medina, NY | 2013 |
| CHILDRENS CANCER AND BLOOD FOUNDATION INC | $179,078 | E61 | published | survivor: cancer | New York, NY | 2024 |
| BLOOD BANK REAL PROPERTY INC | $172,476 | E61 | published | | Kapolei, HI | 2024 |
| Blood For Missions | $153,254 | E61 | inferred 0.80 | | Montclair, CA | 2015 |
| NORTHWEST OKLAHOMA BLOOD INSTITUTE | $134,121 | E61 | inferred 0.90 | | Enid, OK | 2024 |
| BERGEN COMMUNITY BLOOD SVCS FDN | $134,068 | E61 | inferred 0.70 | | Montvale, NJ | 2011 |
| DAK-MINN BLOOD BANK | $122,241 | E61 | inferred 0.90 | | Grand Forks, ND | 2024 |
| Breast Health Inc | $117,004 | E61 | inferred 0.70 | women: issues | Lanham, MD | 2010 |
| FOUNDATION FOR AMERICAS BLOOD CENTE RS | $69,496 | E61 | published | | Washington, DC | 2024 |
| MISSISSIPPI HEADWATERS BLOOD BANK | $41,609 | E61 | inferred 0.90 | | Bemidji, MN | 2014 |
| PLAINS VOLUNTEER AMBULANCE RELIEF ASSOCIATION INC | $34,225 | E61 | inferred 0.60 | | Plains, PA | 2011 |
| EAST CENTRAL OKLAHOMA BLOOD INSTITUTE | $30,785 | E61 | published | | Ada, OK | 2024 |
| COVID PLASMA INITIATIVE FOUNDATION | $10,501 | E61 | published | | Chestnut Rdg, NY | 2024 |
| LLOYD-GOODWIN FOUNDATION INC | $8,893 | E61 | published | | Suwanee, GA | 2025 |
| OTTAWA RETIREMENT PLAZA INC | $6,978 | E61 | inferred 0.55 | | Cincinnati, OH | 2020 |
| THE BLOOD CENTER OF NEW JERSEY | $2,141 | E61 | inferred 0.93 | | Iselin, NJ | 2016 |
| SOUTHERN OKLAHOMA BLOOD INSTITUTE | $1,197 | E61 | published | | Ardmore, OK | 2024 |
| GLORIA'S HOPE FOUNDATION INC | $130 | E61 | inferred 0.20 | | Norcross, GA | 2010 |
| RHIANA'S WYNNING TEAM | $44 | E61 | inferred 0.55 | | Saugus, CA | 2021 |
| UNITED HOMES FUND INC | $0 | E61 | inferred 0.45 | science: research education | Flushing, NY | 2023 |