| CATALIGHT FOUNDATION | $393,024,856 | E50 | published | | Walnut Creek, CA | 2025 |
| SPORTS PHYSICALTHERAPY OCCUPATIONAL THERAPY AND REHABILITATION SERVICE | $198,872,955 | E50 | published | | Westbury, NY | 2024 |
| JOHNS HOPKINS PHARMAQUIP INC | $147,587,515 | E50 | published | | Baltimore, MD | 2024 |
| PHILADELPHIA POST-ACUTE PARTNERSLLC | $117,936,227 | E50 | published | | Allentown, PA | 2024 |
| WEST VIRGINIA FIRST FOUNDATION INC | $91,000,225 | E50 | published | | Bridgeport, WV | 2024 |
| REHAB JV LLC | $89,863,707 | E50 | published | science: research education | Richmond, VA | 2024 |
| EASTER SEALS METROPOLITAN CHICAGO INC | $78,391,883 | E50 | published | | Chicago, IL | 2024 |
| EASTERSEALS ARKANSAS | $64,855,946 | E50 | published | | Little Rock, AR | 2024 |
| ANTHONY WAYNE REHABILITATION CENTER FOR HANDICAPPED & BLIND | $61,055,714 | E50 | published | | Fort Wayne, IN | 2024 |
| EASTER SEALS NEW JERSEY INC | $57,163,500 | E50 | published | shelter: homeless | Jamesburg, NJ | 2024 |
| SOUTHEASTERN KENTUCKY REHABILITATION INDUSTRIES INC | $50,592,593 | E50 | published | | Corbin, KY | 2024 |
| REHABILITATION HOSPITAL OF INDIANA INC | $47,116,155 | E50 | published | | Indianapolis, IN | 2024 |
| COMMISSION ON ACCREDITATION OF REHABILITATION FACILITIES | $46,365,447 | E50 | published | | Tucson, AZ | 2025 |
| QUALITY LIVING INC | $44,993,482 | E50 | published | | Omaha, NE | 2024 |
| LIFESTREAM INC | $44,928,903 | E50 | published | | New Bedford, MA | 2024 |
| VILLA MARIA NURSING & REHABILITATION CENTER | $43,207,705 | E50 | published | | North Miami, FL | 2024 |
| MORRISON CHILD & FAMILY SERVICES | $41,217,162 | E50 | published | girls boys: boys | Portland, OR | 2024 |
| BROOKS HOME CARE ADVANTAGE | $37,306,163 | E50 | published | | Jacksonville, FL | 2024 |
| EASTER SEALS DELAWARE & MARYLANDS EASTERN SHORE INC | $37,229,468 | E50 | published | | New Castle, DE | 2024 |
| CHILDSERVE HABILITATION CENTER INC | $37,220,431 | E50 | published | | Johnston, IA | 2024 |
| THE CHARLES LEA CENTER INC | $36,609,818 | E50 | published | | Spartanburg, SC | 2023 |
| ST JOHNS REHABILITATION HOSPITAL AND NURSING CENTER INC | $28,244,100 | E50 | published | | Laud Lakes, FL | 2024 |
| HUMANIM INC | $28,006,581 | E50 | published | | Columbia, MD | 2024 |
| HEARTSPRING INC | $27,933,896 | E50 | published | | Wichita, KS | 2024 |
| JOHN HEINZ INSTITUTE OF REHABILITATION MEDICINE | $25,933,027 | E50 | published | | Clarks Summit, PA | 2024 |
| MEETING STREET | $25,603,919 | E50 | published | science: research education | Providence, RI | 2024 |
| THE COMMUNITY AT ROCKHILL | $25,121,147 | E50 | published | | Sellersville, PA | 2024 |
| EASTER SEALS SOUTHWEST FLORIDA INC | $23,521,129 | E50 | published | | Sarasota, FL | 2024 |
| EASTER SEALS ALABAMA INC | $23,326,266 | E50 | published | | Montgomery, AL | 2024 |
| PACE AT HOME INC | $23,174,198 | E50 | published | | Newton, NC | 2024 |
| LIFESCAPE FOUNDATION | $22,558,944 | E50 | published | | Sioux Falls, SD | 2024 |
| CROSSROADS REHABILITATION CENTER INC | $22,433,671 | E50 | published | | Indianapolis, IN | 2024 |
| EASTERSEALS FLORIDA INC | $21,662,947 | E50 | published | | Daytona Beach, FL | 2024 |
| EASTER SEALS TENNESSEE INC | $21,197,188 | E50 | published | | Brentwood, TN | 2024 |
| THE FISTULA FOUNDATION | $21,118,320 | E50 | published | women: issues | San Jose, CA | 2024 |
| CAROLINA SENIORCARE | $20,867,038 | E50 | published | | Newton, NC | 2024 |
| EASTER SEALS SOUTH FLORIDA INC | $20,055,420 | E50 | published | | Miami, FL | 2024 |
| TRADEWINDS SERVICES INC | $20,052,252 | E50 | published | | Merrillville, IN | 2024 |
| EASTER SEALS OF SOUTHEASTERN PENNSYLVANIA | $19,882,429 | E50 | published | | Philadelphia, PA | 2024 |
| KATHERINE LUTHER RESIDENTIAL HEALTHCARE & REHABILITATION CENTER INC | $19,670,367 | E50 | published | | Clinton, NY | 2024 |
| EASTER SEALS MASSACHUSETTS INC | $19,414,434 | E50 | published | | Worcester, MA | 2024 |
| EASTER SEALS REHABILITATION CENTER INC | $19,275,207 | E50 | published | | Evansville, IN | 2024 |
| FREE WHEELCHAIR MISSION | $19,147,683 | E50 | published | | Irvine, CA | 2024 |
| EASTER SEAL REHABILITATION CENTER | $18,893,292 | E50 | inferred 0.60 | shelter: homeless | Waterbury, CT | 2024 |
| THE BLEEDING AND CLOTTING DISORDERS INSTITUTE | $18,328,117 | E50 | published | | Peoria, IL | 2024 |
| EASTER SEALS GOODWILL ND INC | $17,825,257 | E50 | published | | Mandan, ND | 2024 |
| VERSITI BLOOD RESEARCH INSTITUTE FOUNDATION INC | $17,317,531 | E50 | published | science: research education | Milwaukee, WI | 2024 |
| SUBURBAN-NRH MEDICAL REHABILITATION INC | $17,011,890 | E50 | published | | Washington, DC | 2024 |
| EASTER SEALS SOUTHERN GEORGIA INC | $16,955,800 | E50 | published | | Albany, GA | 2024 |
| EASTER SEALS HAWAII | $16,738,076 | E50 | published | shelter: disaster | Honolulu, HI | 2025 |
| PYRAMID INC | $16,528,975 | E50 | published | | Pensacola, FL | 2025 |
| EASTER SEAL REHABILITATION CENTER INC | $16,276,344 | E50 | published | | San Antonio, TX | 2024 |
| WILLOWOOD OF GREAT BARRINGTON INC | $15,989,740 | E50 | published | | Pittsfield, MA | 2024 |
| EASTER SEALS RIO GRANDE VALLEY | $15,793,366 | E50 | published | | Mcallen, TX | 2024 |
| CURATIVE CARE NETWORK INC | $15,572,464 | E50 | published | | Milwaukee, WI | 2024 |
| HARMONY SERVICES INC | $15,425,548 | E50 | published | | Brooklyn, NY | 2024 |
| MACON RESOURCES INC | $15,091,101 | E50 | published | | Decatur, IL | 2024 |
| INSTITUTE FOR REHABILITATION & RESEARCH FOUNDATION | $14,545,995 | E50 | published | abuse: substance | Houston, TX | 2025 |
| COMMUNITY REHABILITATION SERVICES INC | $14,488,797 | E50 | published | | Macon, GA | 2024 |
| CHILDRENS THERAPY CENTER | $14,156,803 | E50 | published | | Kent, WA | 2024 |
| POSITIVE ASSISTANCE | $14,077,828 | E50 | published | | Orlando, FL | 2024 |
| JHA GERIATRIC SERVICES INC | $13,748,526 | E50 | published | | Reseda, CA | 2024 |
| LIFE-SKILLS HOME TRAINING TUTORIAL PROGRAM FOR PRE-SCHOOLERS INC | $13,288,804 | E50 | published | | Flushing, NY | 2024 |
| HMS SCHOOL FOR CHILDREN WITH CEREBRAL PALSY | $13,048,625 | E50 | published | | Philadelphia, PA | 2024 |
| KENTUCKY EASTER SEAL SOCIETY INC | $12,906,582 | E50 | published | | Lexington, KY | 2024 |
| CHOICE IN AGING | $12,750,533 | E50 | published | | Pleasant Hill, CA | 2024 |
| SAM SCHMIDT FOUNDATION | $12,657,600 | E50 | published | | Indianapolis, IN | 2024 |
| ABILITY HOUSING INC | $12,137,595 | E50 | published | | Jacksonville, FL | 2025 |
| PASO DEL NORTE CHILDRENS DEVELOPMENT CENTER | $12,118,048 | E50 | published | | El Paso, TX | 2024 |
| DORA ROBERTS REHABILITATION CENTER | $12,094,539 | E50 | published | | Big Spring, TX | 2024 |
| PHYSICAL MEDICINE SPECIALISTS INC | $11,788,964 | E50 | published | | Jacksonville, FL | 2024 |
| BLUE RIDGE PRESERVATION INC | $11,685,404 | E50 | published | | Nashua, NH | 2024 |
| MOMENTUM WHEELS FOR HUMANITY | $11,511,827 | E50 | published | | Chatsworth, CA | 2024 |
| ARIA HEALTH ORTHOPAEDICS | $11,326,359 | E50 | published | | Langhorne, PA | 2024 |
| ATTLEBORO ENTERPRISES INCORPORATED | $10,925,080 | E50 | published | girls boys: boy scouts | North Attleboro, MA | 2024 |
| EASTER SEALS-CENTRAL TEXAS INC | $10,785,669 | E50 | published | | Austin, TX | 2024 |
| BIRTH TO THREE DEVELOPMENTAL CENTER | $10,637,036 | E50 | published | | Federal Way, WA | 2025 |
| RONALD MCDONALD HOUSE CHARITIES OF SOUTH FLORIDA INC | $10,618,621 | E50 | published | girls boys: boys girls clubs | Miami, FL | 2025 |
| REDWOOD SCHOOL & REHABILITATION CENTER INC | $10,460,753 | E50 | published | | Ft Mitchell, KY | 2024 |
| OZARK INDEPENDENT LIVING | $10,366,963 | E50 | published | | West Plains, MO | 2024 |
| SACRED HEART REHABILITATION INSTITUTE INC | $10,283,738 | E50 | published | | Saint Louis, MO | 2024 |
| POTOMAC CASE MANAGEMENT SERVICES INC | $9,997,255 | E50 | published | | Hagerstown, MD | 2023 |
| PENFIELD CHILDRENS CENTER | $9,956,763 | E50 | published | | Milwaukee, WI | 2024 |
| EASTER SEALS DUPAGE AND THE FOX VALLEY REGION | $9,955,633 | E50 | published | | Villa Park, IL | 2024 |
| WARRIORS & QUIET WATERS FOUNDATION | $9,828,674 | E50 | published | | Bozeman, MT | 2025 |
| EASTER SEAL SOCIETY OF SUPERIOR CALIFORNIA | $9,767,045 | E50 | published | | Sacramento, CA | 2024 |
| EVERETT TRANSITIONAL CARE SERVICES | $9,664,085 | E50 | published | | Mill Creek, WA | 2024 |
| BROWARD CHILDRENS CENTER INC | $9,623,978 | E50 | published | | Pompano Beach, FL | 2023 |
| CRYSTAL LAKE SUPPORTIVE ENVIRONMENTS INC | $9,475,101 | E50 | published | science: research education | Orlando, FL | 2025 |
| POTOMAC COMPREHENSIVE DIAGNOSTIC AND GUIDANCE CENTER INC | $9,467,358 | E50 | published | | Romney, WV | 2024 |
| REIMAGINE NETWORK | $9,415,922 | E50 | published | | Santa Ana, CA | 2024 |
| SCHREIBER CENTER FOR PEDIATRIC DEVELOPMENT | $9,364,549 | E50 | published | | Lancaster, PA | 2024 |
| CHILDRENS REHABILITATION CENTER INC | $9,019,106 | E50 | inferred 0.70 | | Yonkers, NY | 2024 |
| TWO-6 RESOURCES INC | $8,926,032 | E50 | published | | Orlando, FL | 2025 |
| HPS HELPING PEOPLE SUCCEED INC | $8,748,497 | E50 | published | | Jensen Beach, FL | 2024 |
| CENTRO DE AYUDA Y TERAPIA AL NINO CON IMPEDIMENTO INC | $8,516,008 | E50 | published | | Moca, PR | 2025 |
| TURNSTONE CENTER FOR CHILDREN AND ADULTS WITH DISABILITIES INC | $8,511,558 | E50 | published | | Fort Wayne, IN | 2024 |
| SOCIEDAD DE EDUCACION Y REHABILITACION SER DE P R | $8,290,617 | E50 | published | | San Juan, PR | 2024 |
| 1ST CEREBRAL PALSY OF NEW JERSEY INC | $7,798,396 | E50 | inferred 0.70 | | Belleville, NJ | 2024 |
| OCCUPATIONAL CENTER OF UNION COUNTY INC | $7,737,692 | E50 | published | | Roselle, NJ | 2024 |