| MEMORIAL HEALTH SERVICES GROUP RETURN | $3,129,989,503 | E12 | published | abuse: substance | Fountain Vly, CA | 2024 |
| MEMORIAL SLOAN-KETTERING CANCER CENTER | $1,819,162,205 | E12 | published | domestic violence | New York, NY | 2024 |
| DIGNITY HEALTH MEDICAL FOUNDATION | $1,549,703,487 | E12 | published | | Phoenix, AZ | 2024 |
| PFIZER PATIENT ASSISTANCE FOUNDATION INC | $1,515,925,015 | E12 | published | | New York, NY | 2024 |
| YALE NEW HAVEN HEALTH SERVICES CORPORATION | $1,157,413,267 | E12 | published | survivor: cancer | New Haven, CT | 2024 |
| SISTERS OF CHARITY OF LEAVENWORTH HEALTH SYSTEM INC | $990,709,227 | E12 | published | | Broomfield, CO | 2024 |
| FACULTY PHYSICIANS AND SURGEONS OF LLUSM | $768,738,258 | E12 | published | | Loma Linda, CA | 2024 |
| JEFFERSON HEALTH CORPORATION | $739,565,671 | E12 | published | science: research education | Philadelphia, PA | 2011 |
| ALFRED I DUPONT CHARITABLE TRUST | $498,778,461 | E12 | published | science: research education | Jacksonville, FL | 2024 |
| MEMORIAL HEALTH SERVICES | $484,020,259 | E12 | published | | Fountain Vly, CA | 2024 |
| MEMORIAL HEALTH SERVICES | $377,304,332 | E12 | published | | Fountain Vly, CA | 2020 |
| FLORIDA ESSENTIAL HEALTHCARE PARTNERSHIPS FOUNDATION INC | $359,713,742 | E12 | published | | Austin, TX | 2024 |
| NEW YORK-PRESBYTERIAN FUND INC | $334,790,100 | E12 | published | science: research education | New York, NY | 2024 |
| VIDANT MEDICAL GROUP LLC | $322,274,004 | E12 | published | | Greenville, NC | 2024 |
| THE ASSOCIATION OF CHRMC AND UNIVERSITY PHYSICIANS | $315,189,862 | E12 | published | | Seattle, WA | 2024 |
| METHODIST HEALTHCARE MINISTRIES OF SOUTH TEXAS INC | $312,051,463 | E12 | published | abuse: child | San Antonio, TX | 2024 |
| DALLAS SAFETY NET SUPPORT CORPORATION | $305,639,809 | E12 | published | | Dallas, TX | 2024 |
| BEACON HEALTH SYSTEM INC | $302,384,065 | E12 | published | | South Bend, IN | 2024 |
| ASSOCIATED PHYSICIANS OF HARVARD FACULTY PHYSICIANS AT BETH ISREAL | $286,190,282 | E12 | published | launch: launch | Boston, MA | 2024 |
| SEATTLE CHILDRENS FOUNDATION | $232,072,474 | E12 | inferred 0.60 | violence: gun | Seattle, WA | 2024 |
| HEALTH QUALITY PARTNERS OF SOUTHERN CALIFORNIA | $205,707,381 | E12 | published | abuse: substance | San Diego, CA | 2024 |
| PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY | $180,131,815 | E12 | published | science: research education | San Francisco, CA | 2025 |
| WAKE FOREST UNIVERSITY BAPTIST MEDICAL CENTER | $172,627,029 | E12 | published | survivor: cancer | Winstonsalem, NC | 2024 |
| SPARROW HEALTH SYSTEM | $166,529,589 | E12 | published | women: issues | Lansing, MI | 2024 |
| HUDSON EAST RIVER SYSTEMS LLC | $156,888,599 | E12 | published | | New York, NY | 2024 |
| ATRIUM HEALTH FOUNDATION | $150,109,810 | E12 | published | science: research education | Charlotte, NC | 2024 |
| PENN HIGHLANDS HEALTHCARE | $148,502,978 | E12 | published | | Du Bois, PA | 2024 |
| EASTER SEALS UCP NORTH CAROLINA & VIRGINIA INC | $142,997,456 | E12 | published | abuse: substance | Raleigh, NC | 2024 |
| JEFFERSON HEALTH CORPORATION | $131,366,695 | E12 | published | | Philadelphia, PA | 2011 |
| NORTHWEST COMMUNITY HEALTHCARE | $131,361,763 | E12 | published | | Arlington Hts, IL | 2024 |
| NORTHWELL HEALTH FOUNDATION | $123,518,750 | E12 | published | | Westbury, NY | 2024 |
| CHILDRENS HOSPITAL FOUNDATION | $117,997,955 | E12 | published | | Washington, DC | 2024 |
| UNIVERSITY OF MARYLAND FACULTY PHYSICIANS INC | $108,819,240 | E12 | published | | Baltimore, MD | 2024 |
| BAYLOR HEALTH CARE SYSTEM FOUNDATION | $104,199,720 | E12 | published | women: issues | Dallas, TX | 2024 |
| BOSTON CHILDRENS HEART FOUNDATION | $101,358,161 | E12 | published | science: research education | Boston, MA | 2024 |
| HEARTHSTONE SENIOR COMMUNITIES INC | $100,712,066 | E12 | published | | Bala Cynwyd, PA | 2024 |
| ARKANSAS CHILDRENS FOUNDATION | $99,223,863 | E12 | published | science: research education | Little Rock, AR | 2024 |
| CHILDRENS ORTHOPAEDIC SURGERY FOUNDATION INC | $93,476,479 | E12 | published | science: research education | Boston, MA | 2024 |
| SEATTLE CHILDRENS HEALTHCARE SYSTEM | $90,680,689 | E12 | published | violence: gun | Seattle, WA | 2024 |
| INTERMOUNTAIN HEALTHCARE FOUNDATION INC | $88,811,140 | E12 | published | | Salt Lake Cty, UT | 2024 |
| BAPTIST HEALTH SOUTH FLORIDA FOUNDATION INC | $84,259,215 | E12 | published | | Coral Gables, FL | 2024 |
| ELIZABETH GAMBLE DEACONESS HOME ASSOCIATION | $83,186,497 | E12 | published | | Cincinnati, OH | 2024 |
| GOOD SHEPHERD REHABILITATION NETWORK | $82,603,715 | E12 | published | | Allentown, PA | 2024 |
| SWEDISH MEDICAL CENTER FOUNDATION | $77,149,780 | E12 | published | survivor: cancer | Seattle, WA | 2024 |
| GREAT RIVER HEALTH SYSTEM INC | $74,579,186 | E12 | published | | W Burlington, IA | 2024 |
| EDWARD-ELMHURST HEALTHCARE | $63,110,386 | E12 | published | science: research education | Arlington Hts, IL | 2024 |
| SAMS FOUNDATION | $61,395,982 | E12 | published | launch: religious | Washington, DC | 2024 |
| MOSAIC HEALTH SYSTEM | $59,455,072 | E12 | published | | Saint Joseph, MO | 2024 |
| CHMC SURGICAL FOUNDATION INC | $54,882,014 | E12 | published | science: research education | Boston, MA | 2024 |
| CANCER RESEARCH FUND OF THE DAMON RUNYON-WALTER WINCHELL FOUNDATION | $54,683,607 | E12 | published | science: research education | New York, NY | 2024 |
| LANCASTER GENERAL HEALTH | $50,258,924 | E12 | published | science: research education | Lancaster, PA | 2024 |
| SAINT JOHNS HEALTH CENTER FOUNDATION | $47,578,032 | E12 | published | men: issues | Santa Monica, CA | 2024 |
| ADVENTHEALTH FOUNDATION INC | $47,384,162 | E12 | published | women: issues | Altamonte Spg, FL | 2024 |
| ASPIRUS INC | $47,088,956 | E12 | published | | Wausau, WI | 2024 |
| SCOTT & WHITE HEALTHCARE FOUNDATION | $43,030,692 | E12 | published | abuse: child | Dallas, TX | 2024 |
| GUNDERSEN LUTHERAN MEDICAL FOUNDATION INC | $41,658,151 | E12 | published | domestic violence | La Crosse, WI | 2024 |
| FOUNDATION FOR MORRISTOWN MEDICAL CENTER INC | $41,654,876 | E12 | published | | Morristown, NJ | 2024 |
| ADVOCATE CHARITABLE FOUNDATION | $40,020,137 | E12 | published | | Downers Grove, IL | 2024 |
| ANDERSON HEALTHCARE | $38,913,514 | E12 | published | | Maryville, IL | 2024 |
| HONORHEALTH FOUNDATION | $38,132,939 | E12 | published | violence: sexual | Scottsdale, AZ | 2024 |
| ST LUKES HEALTH FOUNDATION LTD | $37,787,060 | E12 | published | | Boise, ID | 2024 |
| KOSAIR CHARITIES COMMITTEE INC | $37,719,505 | E12 | published | survivor: sexual | Louisville, KY | 2024 |
| VALLEY BAPTIST LEGACY FOUNDATION | $35,892,803 | E12 | published | | Harlingen, TX | 2024 |
| IEHP FOUNDATION | $35,711,114 | E12 | published | | Rancho Cucamonga, CA | 2024 |
| CLARKSON REGIONAL HEALTH SERVICES I NC | $35,159,250 | E12 | published | | Omaha, NE | 2024 |
| JEFFERSON HEALTH CORPORATION | $31,134,117 | E12 | published | | Philadelphia, PA | 2011 |
| CHILDRENS HEALTHCARE OF CALIFORNIA | $30,848,439 | E12 | published | | Orange, CA | 2024 |
| MARY FREE BED REHABILITATION HOSPITAL FOUNDATION | $30,792,914 | E12 | published | | Grand Rapids, MI | 2024 |
| INTERMOUNTAIN COMMUNITY CARE FOUNDATION INC | $28,292,130 | E12 | published | women: issues | Salt Lake Cty, UT | 2024 |
| GLOBAL HEALTH INVESTMENT CORPORATION | $27,759,830 | E12 | published | women: issues | New York, NY | 2024 |
| JEFFERSON HEALTH CORPORATION | $27,406,437 | E12 | published | science: research education | Philadelphia, PA | 2024 |
| CYBERSPACE INNOVATION CENTER INCOPORATED | $26,220,911 | E12 | published | science: research education | Bossier City, LA | 2024 |
| ALLIED SERVICES FOUNDATION | $25,763,705 | E12 | published | | Clarks Summit, PA | 2024 |
| CHILDRENS HEALTH CARE FOUNDATION | $25,529,747 | E12 | published | | Minneapolis, MN | 2024 |
| MID COAST HEALTH SYSTEM | $25,269,907 | E12 | published | | El Campo, TX | 2024 |
| HOPEWAY FOUNDATION | $24,747,517 | E12 | published | | Charlotte, NC | 2025 |
| IOWA HEALTH FOUNDATION | $24,555,903 | E12 | published | | Des Moines, IA | 2024 |
| COMMUNITY HEALTH NETWORK FOUNDATION INC | $24,411,462 | E12 | published | violence: sexual | Indianapolis, IN | 2024 |
| UNITED BREAST CANCER FOUNDATION INC | $24,061,440 | E12 | published | domestic: workers | Huntington, NY | 2024 |
| CHILDRENS HEALTH FOUNDATION INC | $23,465,847 | E12 | published | science: research education | Norfolk, VA | 2024 |
| PARKLAND FOUNDATION | $23,161,710 | E12 | published | | Dallas, TX | 2024 |
| VAIL HEALTH SERVICES FOUNDATION | $23,063,060 | E12 | published | survivor: cancer | Vail, CO | 2024 |
| TMC HEALTHCARE | $22,100,029 | E12 | published | | Tucson, AZ | 2024 |
| NEW YORK HOSPITAL CORNELL MEDICAL CENTER FUND INC | $21,781,537 | E12 | published | science: research education | New York, NY | 2024 |
| BROWN PHYSICIANS INC | $21,577,866 | E12 | published | | Providence, RI | 2024 |
| VALLEY CHILDRENS HEALTHCARE FOUNDATION | $21,395,032 | E12 | published | | Madera, CA | 2024 |
| SANFORD HEALTH FOUNDATION MARSHFIELD CLINIC INC | $19,386,245 | E12 | published | | Marshfield, WI | 2024 |
| POINT32HEALTH FOUNDATION INC | $19,273,925 | E12 | published | abuse: elder | Canton, MA | 2024 |
| MAINHEALTH SERVICES | $19,103,467 | E12 | published | science: research education | Portland, ME | 2024 |
| MULTICARE FOUNDATIONS | $17,824,340 | E12 | published | abuse: substance | Tacoma, WA | 2024 |
| FLOYD-POLK HEALTHCARE FOUNDATION INC | $17,345,626 | E12 | published | | Rome, GA | 2024 |
| JACKSON MEDICAL MALL FOUNDATION | $17,266,778 | E12 | published | | Jackson, MS | 2024 |
| METROHEALTH FOUNDATION INC | $17,077,737 | E12 | published | launch: aviation | Cleveland, OH | 2025 |
| MENTAL HEALTH INNOVATION FOUNDATION | $16,169,090 | E12 | published | | Omaha, NE | 2024 |
| JOE DIMAGGIO CHILDRENS HOSPITAL FOUNDATION INC | $15,963,540 | E12 | published | | Hollywood, FL | 2025 |
| FINGER LAKES HEALTH FOUNDATION INC | $15,908,700 | E12 | published | | Geneva, NY | 2024 |
| MAINE HEALTH ACCESS FOUNDATION INC | $15,777,926 | E12 | published | violence: gun | Augusta, ME | 2024 |
| JEFFERSON HEALTH CORPORATION | $15,208,391 | E12 | published | science: research education | Philadelphia, PA | 2011 |
| MEMORIAL FOUNDATION INC | $15,096,633 | E12 | inferred 0.85 | | Belleville, IL | 2024 |
| NEWCOURTLAND ELDER SERVICE | $14,939,065 | E12 | published | science: research education | Philadelphia, PA | 2024 |