| SHELBY COUNTY HEALTH CARE CORPORATION | $809,133,452 | E05 | published | science: research education | Memphis, TN | 2024 |
| CITY OF HOPE | $369,822,441 | E05 | published | survivor: cancer | Duarte, CA | 2024 |
| UNITED STATES PHARMACOPEIAL CONVENTION INC | $357,720,644 | E05 | published | science: research education | Rockville, MD | 2024 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE | $252,324,428 | E05 | published | science: research education | Kansas City, KS | 2024 |
| HEALTHEAST MEDICAL RESEARCH INSTITUTE | $171,265,869 | E05 | published | shelter: homeless | Minneapolis, MN | 2024 |
| GATES MEDICAL RESEARCH INSTITUTE | $132,834,027 | E05 | published | | Cambridge, MA | 2024 |
| ROGOSIN INSTITUTE INC | $122,755,452 | E05 | published | science: research education | New York, NY | 2024 |
| OTTAWA HOSPITAL RESEARCH INSTITUTE | $113,187,858 | E05 | published | | Canada | 2025 |
| NEW YORK EHEALTH COLLABORATIVE INC | $93,358,760 | E05 | published | | Albany, NY | 2024 |
| THE AURUM INSTITUTE NPC | $75,953,507 | E05 | published | men: issues | South Africa | 2025 |
| TMF HEALTH QUALITY INSTITUTE | $53,160,586 | E05 | published | science: research education | Austin, TX | 2024 |
| INATAI FOUNDATION | $42,472,731 | E05 | published | | Seattle, WA | 2024 |
| ALL CHILDRENS RESEARCH INSTITUTE INC | $19,819,115 | E05 | published | science: research education | St Petersburg, FL | 2024 |
| HEKTOEN INSTITUTE FOR MEDICAL RESEARCH | $18,868,833 | E05 | published | abuse: substance | Chicago, IL | 2024 |
| MOUNTAIN PACIFIC QUALITY HEALTH | $18,427,690 | E05 | published | abuse: substance | Helena, MT | 2024 |
| EMPIRE HEALTH FOUNDATION | $14,721,923 | E05 | published | launch: launch | Spokane, WA | 2024 |
| HEALTHEWAY INC | $11,802,034 | E05 | published | | Vienna, VA | 2024 |
| CENTER FOR HEALTH CARE STRATEGIES INC | $11,574,666 | E05 | published | | Hamilton, NJ | 2024 |
| GARY AND MARY WEST HEALTH POLICY CENTER INC | $11,337,675 | E05 | published | | La Jolla, CA | 2024 |
| CENTER FOR HEALTH POLICY DEVELOPMENT | $10,917,630 | E05 | inferred 0.60 | abuse: substance | Washington, DC | 2024 |
| NEW YORK ACADEMY OF MEDICINE | $10,636,391 | E05 | published | abuse: substance | New York, NY | 2024 |
| PURCHASER BUSINESS GROUP ON HEALTH | $9,776,826 | E05 | published | | Concord, CA | 2025 |
| HEALTHINSIGHT OF NEVADA | $9,606,181 | E05 | inferred 0.50 | | Salt Lake City, UT | 2012 |
| CLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM INC | $8,901,903 | E05 | published | science: research education | Austin, TX | 2025 |
| REAGAN-UDALL FOUNDATION FOR THE FOOD AND DRUG ADMINISTRATION | $8,703,093 | E05 | inferred 0.50 | science: research education | Washington, DC | 2025 |
| PUBLIC HEALTH ADVOCATES | $8,276,428 | E05 | published | | Davis, CA | 2024 |
| NATIONAL QUALITY FORUM | $8,240,139 | E05 | published | launch: launch | Oakbrook Ter, IL | 2024 |
| GREATER LOS ANGELES VETERANS RESEARCH & EDUCATION FOUNDATION | $7,731,724 | E05 | published | | Los Angeles, CA | 2024 |
| UNITED HOSPITAL FUND OF NEW YORK | $7,502,116 | E05 | published | violence: gun | New York, NY | 2024 |
| WHITMAN-WALKER INSTITUTE INC | $7,484,533 | E05 | published | | Washington, DC | 2024 |
| VALLEYWISE HEALTH FOUNDATION | $7,152,380 | E05 | published | women: issues | Phoenix, AZ | 2025 |
| SURGICAL REVIEW CORPORATION | $6,928,623 | E05 | published | | Raleigh, NC | 2025 |
| SEQUOIA PROJECT | $6,776,108 | E05 | published | | Vienna, VA | 2024 |
| DARTNET INSTITUTE | $6,709,923 | E05 | published | | Aurora, CO | 2024 |
| DRUGS FOR NEGLECTED DISEASESINITIATIVE NORTH AMERICA INC | $6,221,917 | E05 | published | science: research education | New York, NY | 2024 |
| NATIONAL MINORITY QUALITY FORUM INC | $6,042,834 | E05 | inferred 0.60 | science: research education | Washington, DC | 2024 |
| LOUISIANA HEALTH CARE QUALITY FORUM | $5,462,294 | E05 | published | science: research education | Baton Rouge, LA | 2024 |
| MEDICARE RIGHTS CENTER INC | $5,279,102 | E05 | published | | New York, NY | 2024 |
| UNITED STATES OF CARE CAMPAIGN | $5,205,410 | E05 | published | women: issues | Arlington, VA | 2025 |
| HEALTHHIV | $4,507,469 | E05 | published | men: issues | Washington, DC | 2024 |
| ALLIANCE FOR PATIENT ACCESS | $4,387,163 | E05 | published | | Washington, DC | 2024 |
| ST LUKES INSTITUTE FOR HEALTH SCIENCE | $4,307,102 | E05 | published | science: research education | New York, NY | 2024 |
| CALIFORNIAHEALTH PLUS ADVOCATES | $4,268,892 | E05 | published | | Sacramento, CA | 2024 |
| FORWARD TOGETHER | $4,201,662 | E05 | published | women: issues | Oakland, CA | 2024 |
| ICAHN MEDICAL RESEARCH FOUNDATION | $4,027,792 | E05 | published | | Sunny Isles Beach, FL | 2024 |
| CARESTAR FOUNDATION | $3,851,612 | E05 | published | violence: gun | Berkeley, CA | 2024 |
| NATIONAL ALLIANCE OF HEALTHCARE PURCHASER COALITIONS INC | $3,824,925 | E05 | inferred 0.60 | | Washington, DC | 2024 |
| SCL HEALTH RESEARCH INSTITUTE INC | $3,736,826 | E05 | published | | Broomfield, CO | 2024 |
| INSTITUTE FOR COMMUNITY HEALTH INC | $3,628,718 | E05 | published | women: issues | Malden, MA | 2024 |
| ROBARTS RESEARCH INSTITUTE | $3,626,842 | E05 | inferred 0.60 | | London, Ontario | 2011 |
| PARAGON HEALTH INSTITUTE | $3,081,742 | E05 | published | | Arlington, VA | 2025 |
| DRI RESEARCH FOUNDATION | $3,070,169 | E05 | published | | Reno, NV | 2024 |
| CIVITAS NETWORKS FOR HEALTH | $3,053,581 | E05 | published | launch: launch | Sanford, NC | 2025 |
| WISCONSIN HEALTH INFORMATION ORGANIZATION INC | $2,860,974 | E05 | published | | Monona, WI | 2025 |
| MONTANA PUBLIC HEALTH INSTITUTE | $2,828,814 | E05 | published | women: issues | Bozeman, MT | 2025 |
| INSTITUTE FOR MEDICAID INNOVATION INC | $2,780,293 | E05 | published | women: issues | Washington, DC | 2024 |
| FORWARD MT FOUNDATION | $2,615,787 | E05 | published | girls boys: girl scouts | Missoula, MT | 2024 |
| FORCES4QUALITY NORTHEAST OHIO | $2,581,127 | E05 | published | | Brooklyn Hts, OH | 2024 |
| INDEPENDENT HEALTH FOUNDATION | $2,570,804 | E05 | published | abuse: substance | Buffalo, NY | 2024 |
| ONE UTAH HEALTH COLLABORATIVE INC | $2,504,362 | E05 | published | | Salt Lake City, UT | 2024 |
| NATIONAL INSTITUTE FOR HEALTH CARE MANAGEMENT RESEARCH EDUC FDN | $2,490,325 | E05 | published | | Washington, DC | 2025 |
| AMERICAN RHINOLOGIC SOCIETY INC | $2,351,617 | E05 | inferred 0.60 | science: research education | Casa Grande, AZ | 2024 |
| UTAH HEALTH POLICY PROJECT | $2,283,355 | E05 | published | abuse: substance | W Valley City, UT | 2024 |
| BLACK HILLS CENTER FOR AMERICAN INDIAN HEALTH | $2,247,266 | E05 | published | | Rapid City, SD | 2024 |
| EAST TENNESSEE HEALTH INFORMATION NETWORK | $2,187,492 | E05 | inferred 0.50 | | Maryville, TN | 2025 |
| LAKE NONA INSTITUTE INC | $2,118,000 | E05 | published | science: research education | Orlando, FL | 2025 |
| RURAL EMERGENCY TRAUMA INSTITUTE INC | $2,089,014 | E05 | published | | Wheeling, WV | 2024 |
| RURAL BEHAVIORAL HEALTH INSTITUTE | $2,026,784 | E05 | published | | Bozeman, MT | 2024 |
| TRAUMA RESEARCH FOUNDATION INC | $2,024,777 | E05 | published | science: research education | Needham, MA | 2024 |
| NATIONAL CENTER FOR HEALTHCARE LEADERSHIP | $2,012,114 | E05 | published | | Chicago, IL | 2024 |
| HEALTH CARE COST INSTITUTE INC | $2,001,247 | E05 | inferred 0.60 | | Washington, DC | 2012 |
| CATALYST FOR PAYMENT REFORM INC | $1,994,825 | E05 | published | | Long Beach, CA | 2024 |
| MCA TECH PARK INC | $1,985,337 | E05 | published | science: research education | El Paso, TX | 2025 |
| INTERNATIONAL SOCIETY FOR SEXUAL AND INPOTENCE RESEARCH | $1,847,335 | E05 | published | men: issues | Burnsville, MN | 2025 |
| HEALTHCARE INITIATIVES INC | $1,813,826 | E05 | published | science: research education | Indianapolis, IN | 2024 |
| INSTITUTE FOR ADVANCED CONSCIOUSNESS STUDIES INC | $1,805,696 | E05 | published | | Santa Monica, CA | 2024 |
| WILLIAM & ELLA OWENS MEDICAL RESEARCH FOUNDATION | $1,748,680 | E05 | published | science: research education | San Antonio, TX | 2024 |
| VIRGINIA CENTER FOR HEALTH INNOVATION | $1,714,759 | E05 | published | | Midlothian, VA | 2025 |
| THE AMD3 FOUNDATION | $1,712,388 | E05 | published | | Pittsburgh, PA | 2025 |
| PACIFIC VISION FOUNDATION | $1,700,850 | E05 | published | | San Francisco, CA | 2024 |
| NATIONAL INSTITUTE FOR HEALTH CARE REFORM | $1,690,280 | E05 | published | | Auburn Hills, MI | 2024 |
| COLLABORTIVE ALLIANCE FOR NURSING | $1,655,950 | E05 | inferred 0.50 | | San Ramon, CA | 2016 |
| URBAN HEALTH PARTNERSHIPS INCORPORATED | $1,633,420 | E05 | published | | Miami, FL | 2024 |
| NUCLEAR MEDICINE TECHNOLOGY CERTIFICATION BOARD INC | $1,602,273 | E05 | inferred 0.80 | | Tucker, GA | 2024 |
| HEALTHIMPACT | $1,434,249 | E05 | published | | Oakland, CA | 2024 |
| HAYWARD INSTITUTE INC | $1,429,484 | E05 | published | | Winston Salem, NC | 2025 |
| AMERICAN SURGICAL ASSOCIATION | $1,415,803 | E05 | inferred 0.60 | | Beverly, MA | 2024 |
| CENTER FOR POPULATION HEALTH | $1,409,680 | E05 | published | | Johnstown, PA | 2024 |
| The Joint Commission Center for Transforming Healthcare | $1,401,435 | E05 | inferred 0.60 | | Oakbrook Terrace, IL | 2022 |
| NEHI INC | $1,352,527 | E05 | inferred 0.50 | launch: launch | Boston, MA | 2024 |
| KENTUCKY VOICES FOR HEALTH INC | $1,352,350 | E05 | published | | Louisville, KY | 2024 |
| TEACHING KITCHEN COLLABORATIVE INC | $1,335,223 | E05 | published | | Burlington, MA | 2025 |
| INSTITUTE FOR HEALTH POLICY | $1,300,000 | E05 | inferred 0.60 | | Washington, DC | 2024 |
| HIV AND HEPATITIS POLICY INSTITUTE | $1,275,492 | E05 | published | | Washington, DC | 2024 |
| UNITY CONSORTIUM | $1,262,160 | E05 | published | science: research education | Ventnor City, NJ | 2025 |
| MICHIGAN CENTER FOR CLINICAL SYSTEMS IMPROVEMENT | $1,233,838 | E05 | published | | Grand Rapids, MI | 2024 |
| HARC INC | $1,199,989 | E05 | published | violence: gun | Palm Desert, CA | 2024 |
| UTAH ASSOCIATION OF LOCAL HEALTH DEPARTMENTS INC | $1,192,964 | E05 | published | | Brigham City, UT | 2025 |
| MUELLER HEALTH FOUNDATION INC | $1,110,310 | E05 | published | | Woodbridge Townshi, NJ | 2025 |
| PALMETTO PROMISE INSTITUTE | $1,105,360 | E05 | published | | Columbia, SC | 2025 |