Patents
US 9993495 B2: Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung
- Granted
- 2018-06-12
- Filed
- 2016-05-23 application 15162535
- Type
- Utility · 35 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of the present disclosure are suitable for treating primary cancer of the lung, as well as metastatic cancer to the lung and extra pulmonary cancers thereof. Additionally, the present disclosure provides polynucleotide Toll-like receptor 9 agonists with immune stimulatory and toxicity profiles suitable for intrapulmonary administration.
Source: PVGPATDIS, file of 2026-04-10 (ipg180612.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| DYNAVAX TECHNOLOGIES CORPORATION 50 patents | US company or organization | Berkeley, CA | DYNAVAX TECHNOLOGIES CORP SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Cristiana Guiducci | Albany, CA | 14 | PVGPATDIS, file of 2026-04-10 | |
| Robert L. Coffman | Portola Valley, CA | 23 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/713 | PVGPATDIS, file of 2026-04-10 |
| A61N | Electrotherapy; magnetotherapy; radiation therapy; ultrasound therapy | A61N5/00 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/435 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-05-14 | Release of security interest Release of security interest | CRG SERVICING LLC, AS ADMINISTRATIVE AGENT signed 2021-05-13 | DYNAVAX TECHNOLOGIES CORPORATION BERKELEY, CA | 56252/515 | PASDL, file of 2026-10-15 |
| 2018-02-22 | Security interest Security interest Security interest | DYNAVAX TECHNOLOGIES CORPORATION signed 2018-02-20 | CRG SERVICING LLC, AS ADMINISTRATIVE AGENT HOUSTON, TX | 45441/469 | PASDL, file of 2026-10-15 |
| 2016-07-13 | Assignment Assignment of assignor's interest | COFFMAN, ROBERT L. signed 2016-07-07 GUIDUCCI, CRISTIANA signed 2016-07-07 | DYNAVAX TECHNOLOGIES CORPORATION BERKELEY, CA | 39151/182 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.