Patents
US 9868947 B2: Compositions and methods for the construction of a random allelic series
- Granted
- 2018-01-16
- Filed
- 2016-05-04 application 15146621
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure provides a method of making a systematic single point mutation in a target nucleic acid and a method of generating a mutational library comprising target nucleic acids with single point mutations. The mutational library comprises target nucleic acids with single point mutations distributed evenly throughout the target nucleic acid.
Source: PVGPATDIS, file of 2026-04-10 (ipg180116.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Washington University 798 patents | US company or organization | Chesterfield, MO | Washington University in St Louis College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state) WASHINGTON UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| Shriners Hospitals For Children 32 patents | US company or organization | Tampa, FL | SHRINERS HOSPITALS FOR CHILDREN Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Christine Gurnett | Chesterfield, MO | 1 | PVGPATDIS, file of 2026-04-10 | |
| Gabriel Haller | Chesterfield, MO | 1 | PVGPATDIS, file of 2026-04-10 | |
| Matthew Dobbs | Chesterfield, MO | 1 | PVGPATDIS, file of 2026-04-10 | |
| David Alvarado | Chesterfield, MO | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/1031 | PVGPATDIS, file of 2026-04-10 |
| C12P | Fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture | C12P19/40 | PVGPATDIS, file of 2026-04-10 |
| C40B | Combinatorial chemistry; libraries, e.g. chemical libraries | C40B10/00 | PVGPATDIS, file of 2026-04-10 |
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q2525/186 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2018-04-20 | Government interest Confirmatory license | WASHINGTON UNIVERSITY signed 2018-04-19 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 45994/703 | ECORSEXC, file of 2026-09-25 |
| 2017-04-17 | Assignment Assignment of assignor's interest | WASHINGTON UNIVERSITY signed 2017-02-03 | SHRINERS HOSPITALS FOR CHILDREN TAMPA, FL | 42029/431 | ECORSEXC, file of 2026-09-25 |
| 2016-08-30 | Assignment Assignment of assignor's interest | ALVARADO, DAVID signed 2016-08-04 DOBBS, MATTHEW BARRETT signed 2016-08-04 GURNETT, CHRISTINA A. signed 2016-08-04 HALLER, GABRIEL signed 2016-08-04 | WASHINGTON UNIVERSITY ST. LOUIS, MO | 39588/368 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.