Patents
US 9827299 B2: Selectively disrupted whole-cell vaccine
- Granted
- 2017-11-28
- Filed
- 2010-10-12 application 13500925
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention provides for immunogenic compositions and methods for producing an immunogenic composition with multiple immunity-inducing fractions of killed, whole-cell Streptococcus pneumoniae by selectively disrupting a whole cell bacterial preparation in such a manner that a soluble fraction that induces a primarily antibody response, and a cellular fraction that induces a primarily antibody-independent response, remain in the immunogenic composition.
Source: PVGPATDIS, file of 2026-04-10 (ipg171128.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Children's Medical Center Corporation 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| Path Vaccine Solutions 1 patents | US company or organization | Seattle, WA | PATH VACCINE SOLUTIONS Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| FUNDACÃO BUTANTAN 15 patents | Foreign company or organization | São Paulo, BR | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Richard Malley | Beverly, MA | 28 | PVGPATDIS, file of 2026-04-10 | |
| Porter W. Anderson | Key Largo, FL | 1 | PVGPATDIS, file of 2026-04-10 | |
| Yingjie Lu | Dedham, MA | 22 | PVGPATDIS, file of 2026-04-10 | |
| George A. Robertson | Fairfax Station, VA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Mark Alderson | Bainbridge Island, WA | 5 | PVGPATDIS, file of 2026-04-10 | |
| Jean-Francois L. Maisonneuve | Federal Way, WA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Andrea Maria Tate | Issaquah, WA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Waldely de Oliveira Dias | São Paulo, BR | 1 | PVGPATDIS, file of 2026-04-10 | |
| Viviane Maimoni Gonçalves | São Paulo, BR | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K39/092 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2012-05-18 | Assignment Assignment of assignor's interest | DE OLIVEIRA DIAS, WALDELY signed 2012-05-02 MAIMONI GONCALVES, VIVIANE signed 2012-05-02 | FUNDACAO BUTANTAN SAO PAULO | 28231/635 | ECORSEXC, file of 2026-09-25 |
| 2012-04-13 | Assignment Assignment of assignor's interest | PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH signed 2011-01-31 | PATH VACCINE SOLUTIONS SEATTLE, WA | 28039/404 | ECORSEXC, file of 2026-09-25 |
| 2012-04-13 | Assignment Assignment of assignor's interest | ANDERSON, PORTER signed 2010-11-01 LU, YINGJIE signed 2010-11-01 MALLEY, RICHARD signed 2010-11-01 | CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 28039/377 | ECORSEXC, file of 2026-09-25 |
| 2012-04-13 | Assignment Assignment of assignor's interest | ALDERSON, MARK signed 2010-12-13 TATE, ANDREA MARIA signed 2010-12-13 MAISONNEUVE, JEAN-FRANCOIS LUCIEN signed 2010-12-15 ROBERTSON, GEORGE A. signed 2010-12-15 | PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH SEATTLE, WA | 28039/365 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.