Patents

US 9693978 B2: Solvent system for enhancing the solubility of pharmaceutical agents

Granted
2017-07-04
Filed
2015-12-22 application 14977808
Type
Utility · 38 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Liquid and semi-solid pharmaceutical compositions, which can be administered in liquid form or can be used for preparing capsules, are described herein. The composition comprises the salt of one ore more active agents, polyethylene glycol, 0.2-1.0 mole equivalents of a de-ionizing agent per mole of active agent, and water. The pH of the composition is adjusted within the range of 2.5-7.5. The de-ionizing agent causes partial de-ionization (neutralization) of the salt of the active agent resulting in enhanced bioavailability of salts of weakly acidic, basic or amphoteric active agents as well as lesser amounts of polyethylene glycol (PEG) esters.

Source: PVGPATDIS, file of 2026-04-10 (ipg170704.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
BANNER LIFE SCIENCES LLC 38 patentsUS company or organizationHigh Point, NCPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Nachiappan ChidambaramSalt Lake City, UT67PVGPATDIS, file of 2026-04-10
Aqeel A. FatmiGreensboro, NC47PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K31/192PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2017-06-29Assignment
Nunc pro tunc assignment
BANNER LIFE SCIENCES LLC signed 2017-06-22PATHEON SOFTGELS INC HIGH POINT, NC43032/619ECORSEXC, file of 2026-09-25
2016-01-04Assignment
Assignment of assignor's interest
FATMI, AQEEL A. signed 2006-03-27
CHIDAMBARAM, NACHIAPPAN signed 2006-04-03
BANNER PHARMACAPS INC. HIGH POINT, NC37399/553ECORSEXC, file of 2026-09-25
2015-12-22Assignment
Assignment of assignor's interest
BANNER PHARMACAPS INC. signed 2014-11-21BANNER LIFE SCIENCES LLC HIGH POINT, NC37347/567ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.