Patents
US 9610382 B2: Immobilized bioactive hydrogel matrices as surface coatings
- Granted
- 2017-04-04
- Filed
- 2013-11-07 application 14074296
- Type
- Utility · 9 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component, the first and second high molecular weight components each being selected from the group consisting of polyglycans and polypeptides, wherein at least one of the first and second high molecular weight components is immobilized (e.g., by covalent cross-linking) to the surface of the substrate.
Source: PVGPATDIS, file of 2026-04-10 (ipg170404.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| RTI Surgical, Inc. 21 patents | US company or organization | Marquette, MI | RTI SURGICAL, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Francis Vincent Lamberti | Cary, NC | 13 | PVGPATDIS, file of 2026-04-10 | |
| Richard Chris Klann | Washington, NC | 9 | PVGPATDIS, file of 2026-04-10 | |
| Ronald Stewart Hill | Greenville, NC | 11 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61L | Methods or apparatus for sterilising materials or objects in general; disinfection, sterilisation or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads or surgical articles; materials for bandages, dressings, absorbent pads or surgical articles | A61L27/222 | PVGPATDIS, file of 2026-04-10 |
| A61F | Filters implantable into blood vessels; prostheses; devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents; orthopaedic, nursing or contraceptive devices; fomentation; treatment or protection of eyes or ears; bandages, dressings or absorbent pads; first-aid kits | A61F2/0063 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K47/42 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P7/00 | PVGPATDIS, file of 2026-04-10 |
| B29C | Shaping or joining of plastics; shaping of material in a plastic state, not otherwise provided for; after-treatment of the shaped products, e.g. repairing | B29C39/003 | PVGPATDIS, file of 2026-04-10 |
| B29L | Indexing scheme associated with subclass b29c, relating to particular articles | B29L2031/7532 | PVGPATDIS, file of 2026-04-10 |
| Y10T | Technical subjects covered by former us classification | Y10T428/29 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2020-07-21 | Release of security interest Release of security interest | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL | 53260/398 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Release of security interest Release of security interest | ARES CAPITAL CORPORATION, AS AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL PARADIGM SPINE, LLC NEW YORK, NY FOURTH DIMENSION SPINE, LLC NEW YORK, NY | 53257/652 | PASDL, file of 2026-10-15 |
| 2019-03-08 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2019-03-08 PIONEER SURGICAL TECHNOLOGY, INC. signed 2019-03-08 TUTOGEN MEDICAL, INC. signed 2019-03-08 PARADIGM SPINE, LLC signed 2019-03-08 FOURTH DIMENSION SPINE, LLC signed 2019-03-08 | ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT NEW YORK, NY | 48543/505 | PASDL, file of 2026-10-15 |
| 2018-06-06 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2018-06-05 PIONEER SURGICAL TECHNOLOGY, INC. signed 2018-06-05 TUTOGEN MEDICAL, INC. signed 2018-06-05 | JPMORGAN CHASE BANK, N.A., AS THE ADMINISTRATIVE AGENT CHICAGO, IL | 46303/926 | PASDL, file of 2026-10-15 |
| 2013-12-05 | Assignment Assignment of assignor's interest | PIONEER SURGICAL ORTHOBIOLOGICS, INC. signed 2013-09-25 | PIONEER SURGICAL TECHNOLOGY, INC. MARQUETTE, MI | 31721/467 | ECORSEXC, file of 2026-09-25 |
| 2013-12-05 | Merger Merger | ENCELLE, INC. signed 2007-05-31 | PIONEER SURGICAL ORTHOBIOLOGICS, INC. MARQUETTE, MI | 31721/354 | ECORSEXC, file of 2026-09-25 |
| 2013-12-05 | Assignment Assignment of assignor's interest | HILL, RONALD STEWART signed 2003-06-23 LAMBERTI, FRANCIS V. signed 2003-06-23 KLANN, RICHARD CHRIS signed 2003-06-25 | ENCELLE, INC. GREENVILLE, NC | 31721/272 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.