Patents
US 9486484 B2: Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
- Granted
- 2016-11-08
- Filed
- 2014-07-21 application 14336755
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.
Source: PVGPATDIS, file of 2026-04-10 (ipg161108.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| CYTORI THERAPEUTICS, INC. 21 patents | US company or organization | San Diego, CA | CYTORI THERAPEUTICS, INC. State business registration EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Zeni Alfonso | Temecula, CA | 2 | PVGPATDIS, file of 2026-04-10 | |
| John K. Fraser | San Diego, CA | 21 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0651 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/28 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/06 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-08-01 | Correction Corrective assignment to correct the correct assignee's address previously recorded at reel: 049313 frame: 0434. assignor(s) hereby confirms the assignment. | CYTORI THERAPEUTICS, INC. signed 2019-04-24 | LOREM VASCULAR PTE. LTD. SINGAPORE | 49942/204 | ECORSEXC, file of 2026-09-25 |
| 2019-05-17 | Assignment Assignment of assignor's interest | CYTORI THERAPEUTICS, INC. signed 2019-04-24 | LOREM VASCULAR PTE. LTD. MELBOURNE VIC | 49313/434 | ECORSEXC, file of 2026-09-25 |
| 2019-04-25 | Assignment Assignment of assignor's interest | CYTORI THERAPEUTICS, INC. signed 2019-04-24 | LOREM VASCULAR PTE. LTD. SAN DIEGO, CA | 49651/1 | ECORSEXC, file of 2026-09-25 |
| 2019-04-25 | Release of security interest Release of security interest | OXFORD FINANCE LLC signed 2019-04-23 | CYTORI THERAPEUTICS, INC. SAN DIEGO, CA | 49011/347 | ECORSEXC, file of 2026-09-25 |
| 2017-09-22 | Security interest Security interest Security interest | CYTORI THERAPEUTICS, INC. signed 2017-09-20 | OXFORD FINANCE LLC, AS COLLATERAL AGENT ALEXANDRIA, VA | 43952/150 | ECORSEXC, file of 2026-09-25 |
| 2014-09-03 | Assignment Assignment of assignor's interest | ALFONSO, ZENI signed 2014-08-12 FRASER, JOHN K. signed 2014-08-12 | CYTORI THERAPEUTICS, INC. SAN DIEGO, CA | 33660/917 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.