Patents
US 9378407 B2: Automated fish reader using learning machines
- Granted
- 2016-06-28
- Filed
- 2013-09-11 application 14024474
- Type
- Utility · 22 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
An automated reader for reading fluorescence in-situ hybridization signals includes one or more computer processors for receiving a digitized FISH image and executing the steps of converting colors within the image to a hue value, separately for each color extracting quantitative values to detect the presence of signals corresponding to spots and applying a plurality of algorithms to extract features from the signals to determine cell shapes and segment cells within the FISH image. After recombining the signals, the extracted features for the colors learning machines are used to classify the spots according to the color and separate merged signals of classified spots that are in close proximity to each other within the image. The classified spots are counted to determine relative frequency of colors and a report is generated providing the number of classified spots of each color.
Source: PVGPATDIS, file of 2026-04-10 (ipg160628.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| NeoGenomics Laboratories, Inc. 6 patents | Foreign company or organization | Fort Myers, FL | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Hong-Jiang Zhang | Savannah, GA | 55 | PVGPATDIS, file of 2026-04-10 | |
| Maher Albitar | Valley Center, CA | 53 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G06V | Image or video recognition or understanding | G06V20/698 | PVGPATDIS, file of 2026-04-10 |
| G06T | Image data processing or generation, in general | G06T7/0012 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2020-05-11 | Release of security interest Release of security interest | PNC BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT signed 2020-05-04 | NEOGENOMICS LABORATORIES, INC. NAPLES, FL | 52625/295 | ECORSEXC, file of 2026-09-25 |
| 2019-06-28 | Release of security interest Termination and release of security interest in patents | REGIONS BANK, AS COLLATERAL AGENT signed 2019-06-27 | NEOGENOMICS LABORATORIES, INC. FORT MYERS, FL | 49629/235 | ECORSEXC, file of 2026-09-25 |
| 2019-06-28 | Security interest Security interest Notice of grant of security interest in patents | NEOGENOMICS LABORATORIES, INC. signed 2019-06-27 | PNC BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT PITTSBURGH, PA | 49624/512 | ECORSEXC, file of 2026-09-25 |
| 2016-12-23 | Security interest Security interest Notice of grant of security interest in patents | NEOGENOMICS LABORATORIES, INC. signed 2016-12-22 | REGIONS BANK, AS COLLATERAL AGENT ATLANTA, GA | 41182/717 | ECORSEXC, file of 2026-09-25 |
| 2016-12-23 | Release of security interest Release of security interest | WELLS FARGO BANK, NATIONAL ASSOCIATION signed 2016-12-22 | NEOGENOMICS LABORATORIES, INC. FORT MYERS, FL | 40759/963 | ECORSEXC, file of 2026-09-25 |
| 2016-12-22 | Release of security interest Release of security interest | AB PRIVATE CREDIT INVESTORS LLC, AS COLLATERAL AGENT signed 2016-12-22 | CLARIENT DIAGNOSTIC SERVICES, INC. FORT MYERS, FL CLARIENT, INC. FORT MYERS, FL NEOGENOMICS LABORATORIES, INC. FORT MYERS, FL NEOGENOMICS, INC. FORT MYERS, FL PATH LABS, LLC FORT MYERS, FL | 40754/293 | ECORSEXC, file of 2026-09-25 |
| 2016-02-08 | Correction Corrective assignment to correct the oath/declaration previously recorded at reel: 037386 frame: 0383. assignor(s) hereby confirms the security interest. | NEOGENOMICS LABORATORIES, INC. signed 2015-12-30 | WELLS FARGO BANK, NATIONAL ASSOCIATION SANTA MONICA, CA | 37737/199 | ECORSEXC, file of 2026-09-25 |
| 2016-01-05 | Security interest Security interest Security interest | CLARIENT DIAGNOSTIC SERVICES, INC. signed 2015-12-30 CLARIENT, INC. signed 2015-12-30 NEOGENOMICS LABORATORIES, INC. signed 2015-12-30 NEOGENOMICS, INC. signed 2015-12-30 PATH LABS, LLC signed 2015-12-30 | AB PRIVATE CREDIT INVESTORS LLC, AS COLLATERAL AGENT NEW YORK, NY | 37408/921 | ECORSEXC, file of 2026-09-25 |
| 2015-12-30 | Security interest Security interest Security interest | NEOGENOMICS LABORATORIES, INC. signed 2015-12-30 | WELLS FARGO BANK, NATIONAL ASSOCIATION SANTA MONICA, CA | 37386/383 | ECORSEXC, file of 2026-09-25 |
| 2015-03-12 | Assignment Assignment of assignor's interest | ZHANG, HONG signed 2014-12-31 ALBITAR, MAHER signed 2015-02-18 | NEOGENOMICS LABORATORIES FORT MYERS, FL | 35155/790 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.