Patents
US 9370608 B2: Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith
- Granted
- 2016-06-21
- Filed
- 2014-12-12 application 14568339
- Type
- Utility · 26 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the continuous matrix. The composition can be provided in a dehydrated form. The disclosure further provides methods of preparing the composition in a clinically useful form, methods of using the composition in regenerating bone, and kits including the composition.
Source: PVGPATDIS, file of 2026-04-10 (ipg160621.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| RTI Surgical, Inc. 21 patents | US company or organization | Marquette, MI | RTI SURGICAL, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Francis Vincent Lamberti | Cary, NC | 13 | PVGPATDIS, file of 2026-04-10 | |
| Ronald Stewart Hill | Greenville, NC | 11 | PVGPATDIS, file of 2026-04-10 | |
| Adam MacMillan | Quincy, MA | 10 | PVGPATDIS, file of 2026-04-10 | |
| Edward S. Ahn | Dover, MA | 33 | PVGPATDIS, file of 2026-04-10 | |
| Brian M. Schlossberg | Sharon, MA | 10 | PVGPATDIS, file of 2026-04-10 | |
| Stephen Capistron | Melrose, MA | 4 | PVGPATDIS, file of 2026-04-10 | |
| William H. Lloyd | Winterville, NC | 2 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61L | Methods or apparatus for sterilising materials or objects in general; disinfection, sterilisation or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads or surgical articles; materials for bandages, dressings, absorbent pads or surgical articles | A61L27/46 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/0024 | PVGPATDIS, file of 2026-04-10 |
| C08L | Compositions of macromolecular compounds | C08L89/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-08-11 | Security interest Security interest Security interest | XTANT MEDICAL, INC. signed 2024-03-07 BACTERIN INTERNATIONAL, INC. signed 2024-03-07 X-SPINE SYSTEMS, INC. signed 2024-03-07 SURGALIGN SPV, INC. signed 2024-03-07 XTANT MEDICAL HOLDINGS, INC. signed 2024-03-07 | MIDCAP FINANCIAL TRUST BETHESDA, MD | 68539/665 | PASDL, file of 2026-10-15 |
| 2024-08-11 | Security interest Security interest Security interest | XTANT MEDICAL, INC. signed 2024-03-07 BACTERIN INTERNATIONAL, INC. signed 2024-03-07 X-SPINE SYSTEMS, INC. signed 2024-03-07 SURGALIGN SPV, INC. signed 2024-03-07 XTANT MEDICAL HOLDINGS, INC. signed 2024-03-07 | MIDCAP FUNDING IV TRUST BETHESDA, MD | 68539/492 | PASDL, file of 2026-10-15 |
| 2023-12-22 | Correction Security agreement supplement (revolving) | XTANT MEDICAL HOLDINGS, INC. signed 2023-12-18 XTANT MEDICAL, INC. signed 2023-12-18 BACTERIN INTERNATIONAL, INC. signed 2023-12-18 X-SPINE SYSTEMS, INC. signed 2023-12-18 | MIDCAP FUNDING IV TRUST BETHESDA, MD | 66095/652 | PASDL, file of 2026-10-15 |
| 2023-12-22 | Correction Security agreement supplement (term) | XTANT MEDICAL HOLDINGS, INC. signed 2023-12-18 XTANT MEDICAL, INC. signed 2023-12-18 BACTERIN INTERNATIONAL, INC. signed 2023-12-18 X-SPINE SYSTEMS, INC. signed 2023-12-18 | MIDCAP FINANCIAL TRUST BETHESDA, MD | 66095/635 | PASDL, file of 2026-10-15 |
| 2023-10-19 | Merger Merger | PIONEER SURGICAL TECHNOLOGY, INC. signed 2023-06-14 | PIONEER SURGICAL TECHNOLOGY NEWCO, INC. THE WOODLANDS, TX | 65287/641 | PASDL, file of 2026-10-05 |
| 2023-10-11 | Assignment Assignment of assignor's interest | PIONEER SURGICAL TECHNOLOGY NEWCO, INC. signed 2023-08-10 | XTANT MEDICAL HOLDINGS, INC. BELGRADE, MT | 65218/590 | PASDL, file of 2026-10-05 |
| 2021-02-04 | Assignment Assignment of assignor's interest | HILL, RONALD STEWART signed 2012-01-23 LLOYD, WILLIAM H. signed 2012-01-30 CAPISTRON, STEPHEN signed 2012-02-24 MACMILLAN, ADAM signed 2012-02-24 SCHLOSSBERG, BRIAN signed 2012-02-24 LAMBERTI, FRANCIS VINCENT signed 2012-03-02 | PIONEER SURGICAL TECHNOLOGY, INC. MARQUETTE, MI | 55153/194 | ECORSEXC, file of 2026-09-25 |
| 2020-07-21 | Release of security interest Release of security interest | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL | 53260/398 | PASDL, file of 2026-10-15 |
| 2020-07-20 | Release of security interest Release of security interest | ARES CAPITAL CORPORATION, AS AGENT signed 2020-07-20 | RTI SURGICAL, INC. ALACHUA, FL PIONEER SURGICAL TECHNOLOGY, INC. ALACHUA, FL TUTOGEN MEDICAL, INC. ALACHUA, FL PARADIGM SPINE, LLC NEW YORK, NY FOURTH DIMENSION SPINE, LLC NEW YORK, NY | 53257/652 | PASDL, file of 2026-10-15 |
| 2019-03-08 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2019-03-08 PIONEER SURGICAL TECHNOLOGY, INC. signed 2019-03-08 TUTOGEN MEDICAL, INC. signed 2019-03-08 PARADIGM SPINE, LLC signed 2019-03-08 FOURTH DIMENSION SPINE, LLC signed 2019-03-08 | ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT NEW YORK, NY | 48543/505 | PASDL, file of 2026-10-15 |
| 2018-06-06 | Security interest Security interest Security interest | RTI SURGICAL, INC. signed 2018-06-05 PIONEER SURGICAL TECHNOLOGY, INC. signed 2018-06-05 TUTOGEN MEDICAL, INC. signed 2018-06-05 | JPMORGAN CHASE BANK, N.A., AS THE ADMINISTRATIVE AGENT CHICAGO, IL | 46303/926 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.