Patents

US 9260488 B2: Replacement therapy for dental caries

Granted
2016-02-16
Filed
2013-02-22 application 14381524
Type
Utility · 10 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.

Source: PVGPATDIS, file of 2026-04-10 (ipg160216.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Oragenics, Inc 3 patentsUS company or organizationAlachua, FLORAGENICS, INC. State business registration EXACT high confidence: identical full name and state
ORAGENICS INC Form D issuer EXACT high confidence: identical full name and state
ORAGENICS INC SEC filer EXACT medium confidence: identical full name, one of each nationally
PVGPATDIS, file of 2026-04-10
Texas A&M University 14 patentsUS company or organizationCollege Station, TXTEXAS A & M UNIVERSITY Nonprofit EXACT high confidence: identical full name and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Jeffrey Daniel HillmanGainesville, FL14PVGPATDIS, file of 2026-04-10
James L. SmithCollege Station, TX10PVGPATDIS, file of 2026-04-10
Shawanda R. Wilson-StanfordCollege Station, TX2PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A01NPreservation of bodies of humans or animals or plants or parts thereof ; biocides, e.g. as disinfectants, as pesticides or as herbicides ; pest repellants or attractants; plant growth regulatorsA01N63/20PVGPATDIS, file of 2026-04-10
A23GCocoa; cocoa products, e.g. chocolate; substitutes for cocoa or cocoa products; confectionery; chewing gum; ice-cream; preparation thereofA23G4/123PVGPATDIS, file of 2026-04-10
A23LFoods, foodstuffs or non-alcoholic beverages, not otherwise provided for; preparation or treatment thereofA23L2/52PVGPATDIS, file of 2026-04-10
A61KPreparations for medical, dental or toiletry purposesA61K8/64PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P1/02PVGPATDIS, file of 2026-04-10
A61QSpecific use of cosmetics or similar toiletry preparationsA61Q11/00PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K14/195PVGPATDIS, file of 2026-04-10
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N9/0006PVGPATDIS, file of 2026-04-10
A23VIndexing scheme relating to foods, foodstuffs or non-alcoholic beverages and lactic or propionic acid bacteria used in foodstuffs or food preparationA23V2002/00PVGPATDIS, file of 2026-04-10
C12YEnzymesC12Y101/01001PVGPATDIS, file of 2026-04-10
Y02ATechnologies for adaptation to climate changeY02A50/30PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2014-08-29Assignment
Assignment of assignor's interest
HILLMAN, JEFFREY D. signed 2013-03-21ORAGENICS, INC. ALACHUA, FL33639/504ECORSEXC, file of 2026-09-25
2014-08-29Assignment
Assignment of assignor's interest
WILSON-STANFORD, SHAWANDA R. signed 2013-03-25
SMITH, JAMES LEIF signed 2013-04-01
TEXAS A&M UNIVERSITY SYSTEM COLLEGE STATION, TX33639/184ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.