Patents
US 8906866 B2: Antibiotic compositions for the treatment of gram negative infections
- Granted
- 2014-12-09
- Filed
- 2013-03-15 application 13835470
- Type
- Utility · 9 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.
Source: PVGPATDIS, file of 2026-04-10 (ipg141209.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| BioSource Pharm, Inc. 4 patents | US company or organization | Spring Valley, NY | PVGPATDIS, file of 2026-04-10 | |
| Cubist Pharmaceuticals LLC 29 patents | Foreign company or organization | Lexington, MA | CUBIST PHARMACEUTICALS INC SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| William V. Curran | Pearl River, NY | 2 | PVGPATDIS, file of 2026-04-10 | |
| Christopher Matthew Liu | Somerville, MA | 9 | PVGPATDIS, file of 2026-04-10 | |
| Amy C. D. Bombardier | Maynard, MA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Richard A. Leese | Suffern, NY | 4 | PVGPATDIS, file of 2026-04-10 | |
| You Seok Hwang | Concord, MA | 7 | PVGPATDIS, file of 2026-04-10 | |
| Blaise S. Lippa | Acton, MA | 22 | PVGPATDIS, file of 2026-04-10 | |
| Yanzhi Zhang | East Walpole, MA | 2 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K7/62 | PVGPATDIS, file of 2026-04-10 |
| A01N | Preservation of bodies of humans or animals or plants or parts thereof ; biocides, e.g. as disinfectants, as pesticides or as herbicides ; pest repellants or attractants; plant growth regulators | A01N43/713 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/12 | PVGPATDIS, file of 2026-04-10 |
| Y02A | Technologies for adaptation to climate change | Y02A50/30 | PVGPATDIS, file of 2026-04-10 |
| Y10S | Technical subjects covered by former uspc cross-reference art collections [xracs] and digests | Y10S930/19 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-08-08 | Merger Merger | MERCK SHARP & DOHME CORP. signed 2022-04-07 | MERCK SHARP & DOHME LLC RAHWAY, NJ | 61102/145 | PASDL, file of 2026-10-15 |
| 2015-07-09 | Name change Change of name | CUBIST PHARMACEUTICALS, INC. signed 2015-06-29 | CUBIST PHARMACEUTICALS LLC KENILWORTH, NJ | 36084/448 | ECORSEXC, file of 2026-09-25 |
| 2015-07-09 | Assignment Assignment of assignor's interest | CUBIST PHARMACEUTICALS LLC signed 2015-07-09 | MERCK SHARP & DOHME CORP. RAHWAY, NJ | 36046/602 | ECORSEXC, file of 2026-09-25 |
| 2014-01-06 | Assignment Assignment of assignor's interest | ZHANG, YANZHI signed 2011-08-17 BOMBARDIER, AMY C.D. signed 2011-08-19 HWANG, YOU SEOK signed 2011-08-19 LIPPA, BLAISE S. signed 2011-08-19 LIU, CHRISTOPHER M. signed 2011-08-19 | CUBIST PHARMACEUTICALS, INC. LEXINGTON, MA | 31896/452 | ECORSEXC, file of 2026-09-25 |
| 2014-01-06 | Assignment Assignment of assignor's interest | CURRAN, WILLIAM V. signed 2011-09-06 LEESE, RICHARD A. signed 2011-09-06 | BIOSOURCE PHARM, INC. SPRING VALLEY, NY | 31896/422 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.