Patents

US 8722884 B2: Pyrimidine derivatives for the treatment of abnormal cell growth

Granted
2014-05-13
Filed
2006-11-20 application 12095716
Type
Utility · 5 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention relates to salts, solvates and substoichiometric solvates of N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide. The invention also provides pharmaceutical compositions comprising such complexes, as well as methods of treating abnormal cell growth by administering the complexes of the invention.

Source: PVGPATDIS, file of 2026-04-10 (ipg140513.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Verastem, Inc. 13 patentsUS company or organizationCambridge, MAVerastem, Inc. Form D issuer EXACT high confidence: identical full name and state
VERASTEM, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally
PVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
John Charles KathLemon Grove, CA10PVGPATDIS, file of 2026-04-10
Michael Joseph LuzzioNoank, CT32PVGPATDIS, file of 2026-04-10
Susan D. La GrecaOld Lyme, CT3PVGPATDIS, file of 2026-04-10
Nandini Chaturbhai PatelProvidence, RI16PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
C07DHeterocyclic compoundsC07D401/14PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P1/02PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2019-05-16Assignment
Assignment of assignor's interest
PATEL, NANDINI C. signed 2006-08-27
KATH, JOHN CHARLES signed 2006-08-28
LAGRECA, SUSAN D. signed 2006-08-29
LUZZIO, MICHAEL JOSEPH signed 2006-09-14
PFIZER INC. NEW YORK, NY49201/110ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.