Patents
US 8722884 B2: Pyrimidine derivatives for the treatment of abnormal cell growth
- Granted
- 2014-05-13
- Filed
- 2006-11-20 application 12095716
- Type
- Utility · 5 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to salts, solvates and substoichiometric solvates of N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide. The invention also provides pharmaceutical compositions comprising such complexes, as well as methods of treating abnormal cell growth by administering the complexes of the invention.
Source: PVGPATDIS, file of 2026-04-10 (ipg140513.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Verastem, Inc. 13 patents | US company or organization | Cambridge, MA | Verastem, Inc. Form D issuer EXACT high confidence: identical full name and state VERASTEM, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| John Charles Kath | Lemon Grove, CA | 10 | PVGPATDIS, file of 2026-04-10 | |
| Michael Joseph Luzzio | Noank, CT | 32 | PVGPATDIS, file of 2026-04-10 | |
| Susan D. La Greca | Old Lyme, CT | 3 | PVGPATDIS, file of 2026-04-10 | |
| Nandini Chaturbhai Patel | Providence, RI | 16 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D401/14 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P1/02 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-05-16 | Assignment Assignment of assignor's interest | PATEL, NANDINI C. signed 2006-08-27 KATH, JOHN CHARLES signed 2006-08-28 LAGRECA, SUSAN D. signed 2006-08-29 LUZZIO, MICHAEL JOSEPH signed 2006-09-14 | PFIZER INC. NEW YORK, NY | 49201/110 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.