Patents

US 8718994 B2: Ligands for the GLP-1 receptor and methods for discovery thereof

Granted
2014-05-06
Filed
2009-04-08 application 12936434
Type
Utility · 6 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Disclosed is the three-dimensional (3-D) structure of the GLP-1 receptor (GLP-1R) and methods by which the structure may be used to develop compounds that bind to, and/or modulate the GLP-1R. The technology described herein may be applied to the development of compounds that target the GLP-1R, or may be used to develop target compound that may bind to, and/or modulate the activity of the GLP-1R.

Source: PVGPATDIS, file of 2026-04-10 (ipg140506.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
TransTech Pharma, LLC 28 patentsUS company or organizationHigh Point, NCPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Mohan RaoGreensboro, NC9PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N5/0602PVGPATDIS, file of 2026-04-10
G16BBioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or protein-related data processing in computational molecular biologyG16B15/20PVGPATDIS, file of 2026-04-10
G16CComputational chemistry; chemoinformatics; computational materials scienceG16C20/50PVGPATDIS, file of 2026-04-10
G01NInvestigating or analysing materials by determining their chemical or physical propertiesG01N2333/605PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2021-01-27Release of security interest
Release of security interest
HORIZON TECHNOLOGY FINANCE CORPORATION, AS COLLATERAL AGENT signed 2021-01-21VTV THERAPEUTICS LLC HIGH POINT, NC55133/214PASDL, file of 2026-10-15
2018-04-18Security interest Security interest
Security interest
VTV THERAPEUTICS LLC signed 2018-04-09HORIZON TECHNOLOGY FINANCE CORPORATION, AS COLLATERAL AGENT FARMINGTON, CT45969/774PASDL, file of 2026-10-15
2015-09-24Correction
Corrective assignment to correct the receiving party data previously recorded at reel: 036254 frame: 0780. assignor(s) hereby confirms the assignment.
M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29VTVX HOLDINGS I LLC HIGH POINT, NC36675/407ECORSEXC, file of 2026-09-25
2015-08-03Release of security interest
Release of security interest
M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29VTVX HOLDINGS II LLC HIGH POINT, NC36254/780ECORSEXC, file of 2026-09-25
2015-07-31Assignment
Assignment of assignor's interest
VTVX HOLDINGS I LLC signed 2015-07-29VTV THERAPEUTICS LLC HIGH POINT, NC36242/354ECORSEXC, file of 2026-09-25
2015-07-30Name change
Change of name
VTV THERAPEUTICS LLC signed 2015-07-29VTVX HOLDINGS I LLC HIGH POINT, NC36236/165ECORSEXC, file of 2026-09-25
2015-06-25Name change
Change of name
TRANSTECH PHARMA, LLC signed 2015-05-18VTV THERAPEUTICS LLC HIGH POINT, NC36026/219ECORSEXC, file of 2026-09-25
2015-02-26Security interest Security interest
Security interest
TRANSTECH PHARMA, LLC signed 2015-02-25M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT NEW YORK, NY35103/356ECORSEXC, file of 2026-09-25
2014-04-07Release of security interest
Notice of release of security interest in patents for reel/frame 030982/0803
M&F TTP HOLDINGS LLC signed 2014-03-28TRANSTECH PHARMA, LLC HIGH POINT, NC32621/860ECORSEXC, file of 2026-09-25
2013-11-26Assignment
Assignment of assignor's interest
TRANSTECH PHARMA, INC. signed 2013-11-14TRANSTECH PHARMA, LLC HIGH POINT, NC31678/682ECORSEXC, file of 2026-09-25
2013-08-09Security interest Security interest
Security agreement
TRANSTECH PHARMA, INC. signed 2013-08-09M&F TTP HOLDINGS LLC C/O MACANDREWS & FORBES HOLDINGS INC. NEW YORK, NY30982/803ECORSEXC, file of 2026-09-25
2010-10-05Assignment
Assignment of assignor's interest
RAO, MOHAN signed 2009-05-11TRANSTECH PHARMA, INC. HIGH POINT, NC25091/337ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.