Patents
US 8697638 B2: Methods for preparing purified lipopeptides
- Granted
- 2014-04-15
- Filed
- 2008-08-26 application 12198666
- Type
- Utility · 11 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to crystalline and crystal-like forms of lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention relates to methods of purifying lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention also relates to pharmaceutical compositions comprising the purified form of the lipopeptide and methods of using these compositions.
Source: PVGPATDIS, file of 2026-04-10 (ipg140415.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Cubist Pharmaceuticals LLC 29 patents | Foreign company or organization | Lexington, MA | CUBIST PHARMACEUTICALS INC SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Dennis Keith | Montclair, NJ | 4 | PVGPATDIS, file of 2026-04-10 | |
| Jan-Ji Lai | Westborough, MA | 11 | PVGPATDIS, file of 2026-04-10 | |
| Chandrika Govardhan | Lexington, MA | 4 | PVGPATDIS, file of 2026-04-10 | |
| Nazer Khalaf | Milton, MA | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K7/66 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2016-09-14 | Name change Change of address | CUBIST PHARMACEUTICALS LLC signed 2016-07-14 | CUBIST PHARMACEUTICALS LLC 6000 LUCERNE 6 | 40026/743 | PASDL, file of 2026-10-15 |
| 2015-08-14 | Correction Corrective assignment to correct the nature of conveyance previously recorded at reel: 036308 frame: 0207. assignor(s) hereby confirms the release of security interest. | ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT signed 2015-07-07 | CUBIST PHARMACEUTICALS, INC. LEXINGTON, MA ADOLOR CORPORATION EXTON, PA CALIXA THERAPEUTICS, INC. LEXINGTON, MA | 36355/184 | PASDL, file of 2026-10-15 |
| 2015-08-12 | Security interest Security interest Security interest | ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT signed 2015-07-07 | CUBIST PHARMACEUTICALS, INC. LEXINGTON, MA ADOLOR CORPORATION EXTON, PA CALIXA THERAPEUTICS, INC. LEXINGTON, MA | 36308/207 | PASDL, file of 2026-10-15 |
| 2015-08-05 | Name change Change of name | CUBIST PHARMACEUTICALS, INC. signed 2015-06-29 | CUBIST PHARMACEUTICALS LLC KENILWORTH, NJ | 36283/189 | PASDL, file of 2026-10-15 |
| 2014-01-15 | Assignment Assignment of assignor's interest | KEITH, DENNIS signed 2005-07-26 LAI, JAN-JI signed 2005-07-21 GOVARDHAN, CHANDRIKA signed 2005-09-15 KHALAF, NAZER signed 2005-09-15 | CUBIST PHARMACEUTICALS, INC. LEXINGTON, MA | 31974/35 | PASDL, file of 2026-10-15 |
| 2012-11-20 | Security interest Security interest Security agreement | CUBIST PHARMACEUTICALS, INC. signed 2012-11-20 ADOLOR CORPORATION signed 2012-11-20 CALIXA THERAPEUTICS, INC. signed 2012-11-20 CUBIST PHARMACEUTICALS HOLDINGS, INC. signed 2012-11-20 CUBIST PHARMACEUTICALS U.S. signed 2012-11-20 | ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT TORONTO, ONTARIO | 29339/669 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.