Patents
US 8444994 B2: Multivalent antihelminthic vaccine
- Granted
- 2013-05-21
- Filed
- 2009-06-30 application 12999132
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are Necator americanus antigens, although antigens from other hookworm species (e.g. Ancylostoma duodenale) may also be employed. The schistosome antigen is preferably a Schistosoma mansoni or a Schistosoma haematobium antigen although antigens from other schistosome species (e.g. Schistosoma japonicum) may also be employed. In some cases full or partial sequences of schistosome antigens may be fused with full or partial sequences of hookworm {Necator americanus) to produce recombinant chimeric antigens.
Source: PVGPATDIS, file of 2026-04-10 (ipg130521.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Albert B. Sabin Vaccine Institute 1 patents | US company or organization | Washington, DC | THE ALBERT B SABIN VACCINE INSTITUTE INC Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| THE GEORGE WASHINGTON UNIVERSITY 194 patents | US company or organization | Washington, DC | THE GEORGE WASHINGTON UNIVERSITY State business registration EXACT high confidence: identical full name and state THE GEORGE WASHINGTON UNIVERSITY Nonprofit EXACT high confidence: identical full name and state George Washington University College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| The Council of the Queensland Institute of Medical Research 19 patents | Foreign government | Forsayth, AU | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Peter Hotez | Bethesda, MD | 2 | PVGPATDIS, file of 2026-04-10 | |
| Alexander Loukas | Cairns, AU | 2 | PVGPATDIS, file of 2026-04-10 | |
| Mark Pearson | Maroochydore, AU | 1 | PVGPATDIS, file of 2026-04-10 | |
| Jeffrey Bethony | Felixlândia, BR | 2 | PVGPATDIS, file of 2026-04-10 | |
| Bin Zhan | North Potomac, MD | 2 | PVGPATDIS, file of 2026-04-10 | |
| Gaddam Goud | Boyds, MD | 2 | PVGPATDIS, file of 2026-04-10 | |
| Maria Elena Bottazzi | Washington, DC | 2 | PVGPATDIS, file of 2026-04-10 | |
| David Diemert | Washington, DC | 1 | Person page FUZZY high confidence | PVGPATDIS, file of 2026-04-10 |
| Ami Shah Brown | Arbutus, MD | 1 | Person page FUZZY high confidence | PVGPATDIS, file of 2026-04-10 |
| Peter Giacomautonio | Mansfield, AU | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K39/0003 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P33/00 | PVGPATDIS, file of 2026-04-10 |
| Y02A | Technologies for adaptation to climate change | Y02A50/30 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2018-11-01 | Assignment Assignment of assignor's interest | THE ALBERT B. SABIN VACCINE INSTITUTE, INC. signed 2017-04-24 | BAYLOR COLLEGE OF MEDICINE HOUSTON, TX | 47380/907 | ECORSEXC, file of 2026-09-25 |
| 2012-12-19 | Assignment Assignment of assignor's interest | GIACOMANTONIO, PETER signed 2012-11-22 LOUKAS, ALEXANDER signed 2012-11-22 PEARSON, MARK signed 2012-11-22 | THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH HERSTON, QUEENSLAND | 29501/370 | ECORSEXC, file of 2026-09-25 |
| 2012-11-09 | Assignment Assignment of assignor's interest | HOTEZ, PETER signed 2012-11-07 BOTTAZZI, MARIA ELENA signed 2012-11-08 ZHAN, BIN signed 2012-11-08 | THE GEORGE WASHINGTON UNIVERSITY WASHINGTON, DC | 29268/396 | ECORSEXC, file of 2026-09-25 |
| 2012-10-08 | Assignment Assignment of assignor's interest | DIEMERT, DAVID signed 2011-02-25 SHAH BROWN, AMI signed 2011-02-25 | THE ALBERT B. SABIN VACCINE INSTITUTE WASHINGTON, DC | 29088/470 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.