Patents
US 8415384 B2: Reducing myocardial reperfusion injury by the combination therapy of protein kinase A activation and B1-adrenergic receptor blockade
- Granted
- 2013-04-09
- Filed
- 2009-06-12 application 12997485
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Embodiments of the invention are directed to methods of treating reperfusion or resuscitation injury in an individual in need of such treatment, comprising the step of administering to the individual who has had, having, or is at immediate risk of having an ischemic event an amount of a composition comprising a protein kinase A (PKA) activator and a β1-adrenergic receptor antagonist sufficient to reduce reperfusion injury to an ischemic tissue.
Source: PVGPATDIS, file of 2026-04-10 (ipg130409.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 3,356 patents | US company or organization | Austin, TX | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ming-He Huang | League City, TX | 3 | PVGPATDIS, file of 2026-04-10 | |
| Kenichi Fujise | Galveston, TX | 1 | PVGPATDIS, file of 2026-04-10 | |
| Barry F. Uretsky | Barling, AR | 4 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K45/06 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P9/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2011-02-28 | Assignment Assignment of assignor's interest | FUJISE, KENICHI signed 2011-02-10 HUANG, MING-HE signed 2011-02-14 URETSKY, BARRY F. signed 2011-02-25 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM AUSTIN, TX | 25871/957 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.