Patents
US 8377983 B2: Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
- Granted
- 2013-02-19
- Filed
- 2010-02-10 application 12703604
- Type
- Utility · 16 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to compounds and methods from the treatment of cancer. The invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods for the treatment of cancer using the compounds of the presentation invention or pharmaceutical compositions comprising compounds of the present invention.
Source: PVGPATDIS, file of 2026-04-10 (ipg130219.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| TransTech Pharma, LLC 28 patents | US company or organization | High Point, NC | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Adnan M. M. Mjalli | Oak Ridge, NC | 53 | PVGPATDIS, file of 2026-04-10 | |
| Brian S. Grella | High Point, NC | 3 | PVGPATDIS, file of 2026-04-10 | |
| Govindan Subramanian | Fort Lee, NJ | 20 | PVGPATDIS, file of 2026-04-10 | |
| Murty N. Arimilli | Oak Ridge, NC | 3 | PVGPATDIS, file of 2026-04-10 | |
| Ramesh Gopalaswamy | Jamestown, NC | 10 | PVGPATDIS, file of 2026-04-10 | |
| Robert Carl Andrews | Jamestown, NC | 39 | PVGPATDIS, file of 2026-04-10 | |
| Stephen Thomas Davis | Durham, NC | 17 | PVGPATDIS, file of 2026-04-10 | |
| Xiaochuan Guo | High Point, NC | 3 | PVGPATDIS, file of 2026-04-10 | |
| Jeff Zhu | High Point, NC | 14 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D417/14 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2015-09-24 | Correction Corrective assignment to correct the receiving party data previously recorded at reel: 036254 frame: 0780. assignor(s) hereby confirms the assignment. | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29 | VTVX HOLDINGS I LLC HIGH POINT, NC | 36675/407 | ECORSEXC, file of 2026-09-25 |
| 2015-08-03 | Release of security interest Release of security interest | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29 | VTVX HOLDINGS II LLC HIGH POINT, NC | 36254/780 | ECORSEXC, file of 2026-09-25 |
| 2015-02-26 | Security interest Security interest Security interest | TRANSTECH PHARMA, LLC signed 2015-02-25 | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT NEW YORK, NY | 35103/356 | ECORSEXC, file of 2026-09-25 |
| 2014-04-07 | Release of security interest Notice of release of security interest in patents for reel/frame 030982/0803 | M&F TTP HOLDINGS LLC signed 2014-03-28 | TRANSTECH PHARMA, LLC HIGH POINT, NC | 32621/860 | ECORSEXC, file of 2026-09-25 |
| 2013-11-22 | Assignment Assignment of assignor's interest | TRANSTECH PHARMA, INC. signed 2013-11-14 | TRANSTECH PHARMA, LLC HIGH POINT, NC | 31654/878 | ECORSEXC, file of 2026-09-25 |
| 2013-08-09 | Security interest Security interest Security agreement | TRANSTECH PHARMA, INC. signed 2013-08-09 | M&F TTP HOLDINGS LLC C/O MACANDREWS & FORBES HOLDINGS INC. NEW YORK, NY | 30982/803 | ECORSEXC, file of 2026-09-25 |
| 2010-11-23 | Assignment Assignment of assignor's interest | GUO, XIAOCHUAN signed 2007-04-24 GOPALASWAMY, RAMESH signed 2007-04-25 GRELLA, BRIAN S. signed 2007-04-26 SUBRAMANIAN, GOVINDAN signed 2007-04-26 ZHU, JEFF signed 2007-04-26 DAVIS, STEPHEN signed 2007-05-03 ANDREWS, ROBERT C. signed 2007-05-04 MJALLI, ADNAN M.M. signed 2007-05-04 ARIMILLI, MURTY N. signed 2007-05-10 | TRANSTECH PHARMA, INC. HIGH POINT, NC | 25399/876 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.