Patents
US 8299258 B2: Method of making piperidine derivatives
- Granted
- 2012-10-30
- Filed
- 2009-11-04 application 12612089
- Type
- Utility · 7 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to a process for the preparation of piperidine derivatives including sufentanil, and their pharmaceutically acceptable salts, such as the citrate salt in which a quaternary ammonium (nosylate) salt of an appropriate piperidine is reacted with a corresponding 4-NO2 sulfonate ester to produce the desired piperidine derivative at a high purity.
Source: PVGPATDIS, file of 2026-04-10 (ipg121030.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| CAMBREX CHARLES CITY, INC. 9 patents | US company or organization | Charles City, IA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Greg S. Buenger | Charles City, IA | 2 | PVGPATDIS, file of 2026-04-10 | |
| Paul Jass | Charles City, IA | 4 | PVGPATDIS, file of 2026-04-10 | |
| Kezia Peixoto Schutz | Charles City, IA | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D409/06 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-03-06 | Release of security interest Release of first lien security interest in patents | ROYAL BANK OF CANADA signed 2025-03-06 | AVISTA PHARMA SOLUTIONS, INC. EAST RUTHERFORD, NJ CAMBREX CHARLES CITY, INC. EAST RUTHERFORD, NJ SNAPDRAGON CHEMISTRY, INC. EAST RUTHERFORD, NJ | 70438/333 | ECORSEXC, file of 2026-09-25 |
| 2020-12-07 | Release of security interest Release of second lien security interest in patents | ROYAL BANK OF CANADA, AS COLLATERAL AGENT signed 2020-12-07 | AVISTA PHARMA SOLUTIONS, INC. DURHAM, NC | 54630/307 | ECORSEXC, file of 2026-09-25 |
| 2019-12-04 | Release of security interest Notice of release of security interest in patents | WELLS FARGO BANK, NATIONAL ASSOCIATION signed 2019-12-04 | CAMBREX CHARLES CITY, INC. CHARLES CITY, IA | 51283/903 | ECORSEXC, file of 2026-09-25 |
| 2019-12-04 | Security interest Security interest First lien patent security agreement | AVISTA PHARMA SOLUTIONS, INC. signed 2019-12-04 CAMBREX CHARLES CITY, INC. signed 2019-12-04 | ROYAL BANK OF CANADA, AS COLLATERAL AGENT TORONTO | 51283/877 | ECORSEXC, file of 2026-09-25 |
| 2019-12-04 | Security interest Security interest Second lien patent security agreement | AVISTA PHARMA SOLUTIONS, INC. signed 2019-12-04 CAMBREX CHARLES CITY, INC. signed 2019-12-04 | ROYAL BANK OF CANADA, AS COLLATERAL AGENT TORONTO | 51196/80 | ECORSEXC, file of 2026-09-25 |
| 2019-01-03 | Security interest Security interest Security interest | CAMBREX CHARLES CITY, INC. signed 2019-01-02 | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT CHARLOTTE, NC | 47895/53 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.