Patents
US 8222259 B2: 1,2,4-triazolo[4,3-c]pyrimidin-3-one and pyrazolo[4,3-e]-1,2,4-triazolo[4,3-c]pyrimidin-3-one compounds for use as adenosine A2a receptor antagonists
- Granted
- 2012-07-17
- Filed
- 2009-03-03 application 12920924
- Type
- Utility · 21 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Compounds of the Formula I wherein R1 and R2 together with the carbon atoms to which they are bonded optionally form a further heteroaromatic ring of the formula (II) as well as pharmaceutically acceptable salts, solvates, esters and prodrugs thereof are adenosine A2a receptor antagonists and, therefore, are useful in the treatment of central nervous system diseases, in particular Parkinson's disease.
Source: PVGPATDIS, file of 2026-04-10 (ipg120717.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| SCHERING CORPORATION 216 patents | US company or organization | Rahway, NJ | SCHERING CORPORATION State business registration EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Joel M. Harris | Kenilworth, NJ | 33 | PVGPATDIS, file of 2026-04-10 | |
| Bernard R. Neustadt | Kenilworth, NJ | 11 | PVGPATDIS, file of 2026-04-10 | |
| Jinsong Hao | Kenilworth, NJ | 8 | PVGPATDIS, file of 2026-04-10 | |
| Andrew Stamford | Kenilworth, NJ | 92 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D487/14 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-08-08 | Merger Merger | MERCK SHARP & DOHME CORP. signed 2022-04-07 | MERCK SHARP & DOHME LLC RAHWAY, NJ | 61102/145 | PASDL, file of 2026-10-15 |
| 2012-08-30 | Name change Change of name | SCHERING CORPORATION signed 2012-05-02 | MERCK SHARP & DOHME CORP. RAHWAY, NJ | 28884/151 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.