Patents
US 8207221 B2: Crystalline polymorphs of a CXC-chemokine receptor ligand
- Granted
- 2012-06-26
- Filed
- 2008-07-16 application 12174470
- Type
- Utility · 5 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure:These four polymorphic forms, herein referred to as Forms I, II, III and IV are active as a CXC-chemokine receptor ligands. The invention is further directed to formulations, methods of treatment, and processes of synthesis of these polymorphic forms.
Source: PVGPATDIS, file of 2026-04-10 (ipg120626.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| SCHERING CORPORATION 216 patents | US company or organization | Kenilworth, NJ | SCHERING CORPORATION State business registration EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Mengwei Hu | Hackettstown, NJ | 4 | PVGPATDIS, file of 2026-04-10 | |
| Younong Yu | East Brunswick Township, NJ | 33 | PVGPATDIS, file of 2026-04-10 | |
| Michael P. Dwyer | Scotch Plains, NJ | 19 | PVGPATDIS, file of 2026-04-10 | |
| Arthur G. Taveras | Southborough, MA | 30 | PVGPATDIS, file of 2026-04-10 | |
| Agnes S. Kim-Meade | Fanwood, NJ | 3 | PVGPATDIS, file of 2026-04-10 | |
| Jianguo Yin | Plainsboro, NJ | 15 | PVGPATDIS, file of 2026-04-10 | |
| Xiaoyong Fu | Edison, NJ | 16 | PVGPATDIS, file of 2026-04-10 | |
| Timothy L. McAllister | Westfield, NJ | 5 | PVGPATDIS, file of 2026-04-10 | |
| Shuyi Zhang | Parsippany-Troy Hills, NJ | 6 | PVGPATDIS, file of 2026-04-10 | |
| Kevin J. Klopfer | Flemington, NJ | 16 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D307/52 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P1/02 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-08-08 | Merger Merger | MERCK SHARP & DOHME CORP. signed 2022-04-07 | MERCK SHARP & DOHME LLC RAHWAY, NJ | 61102/145 | PASDL, file of 2026-10-15 |
| 2012-08-30 | Name change Change of name | SCHERING CORPORATION signed 2012-05-02 | MERCK SHARP & DOHME CORP. RAHWAY, NJ | 28884/151 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.