Patents
US 8148413 B2: N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes
- Granted
- 2012-04-03
- Filed
- 2010-09-30 application 12895761
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I)wherein A and B are further defined in the application.
Source: PVGPATDIS, file of 2026-04-10 (ipg120403.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| TransTech Pharma, LLC 28 patents | US company or organization | High Point, NC | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jesper Lau | Farum, DK | 49 | PVGPATDIS, file of 2026-04-10 | |
| Per Vedsø | Not reported | 7 | PVGPATDIS, file of 2026-04-10 | |
| Janos Tibor Kodra | Copenhagen, DK | 23 | PVGPATDIS, file of 2026-04-10 | |
| Anthony Murray | Hellerup, DK | 20 | PVGPATDIS, file of 2026-04-10 | |
| Lone Jeppesen | Avenue Madeleine, DK | 10 | PVGPATDIS, file of 2026-04-10 | |
| Michael Ankersen | Randers, DK | 8 | PVGPATDIS, file of 2026-04-10 | |
| Govindan Subramanian | High Point, NC | 20 | PVGPATDIS, file of 2026-04-10 | |
| Adnan M. M. Mjalli | Jamestown, NC | 53 | PVGPATDIS, file of 2026-04-10 | |
| Robert Carl Andrews | Jamestown, NC | 39 | PVGPATDIS, file of 2026-04-10 | |
| Dharma Rao Polisetti | High Point, NC | 49 | PVGPATDIS, file of 2026-04-10 | |
| Daniel P. Christen | High Point, NC | 10 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D401/12 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P3/04 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2015-09-24 | Correction Corrective assignment to correct the receiving party data previously recorded at reel: 036254 frame: 0780. assignor(s) hereby confirms the assignment. | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29 | VTVX HOLDINGS I LLC HIGH POINT, NC | 36675/407 | ECORSEXC, file of 2026-09-25 |
| 2015-08-03 | Release of security interest Release of security interest | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT signed 2015-07-29 | VTVX HOLDINGS II LLC HIGH POINT, NC | 36254/780 | ECORSEXC, file of 2026-09-25 |
| 2015-07-31 | Assignment Assignment of assignor's interest | VTVX HOLDINGS I LLC signed 2015-07-29 | VTV THERAPEUTICS LLC HIGH POINT, NC | 36242/354 | ECORSEXC, file of 2026-09-25 |
| 2015-07-30 | Name change Change of name | VTV THERAPEUTICS LLC signed 2015-07-29 | VTVX HOLDINGS I LLC HIGH POINT, NC | 36236/165 | ECORSEXC, file of 2026-09-25 |
| 2015-06-25 | Name change Change of name | TRANSTECH PHARMA, LLC signed 2015-05-18 | VTV THERAPEUTICS LLC HIGH POINT, NC | 36026/219 | ECORSEXC, file of 2026-09-25 |
| 2015-02-26 | Security interest Security interest Security interest | TRANSTECH PHARMA, LLC signed 2015-02-25 | M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT NEW YORK, NY | 35103/356 | ECORSEXC, file of 2026-09-25 |
| 2014-04-07 | Release of security interest Notice of release of security interest in patents for reel/frame 030982/0803 | M&F TTP HOLDINGS LLC signed 2014-03-28 | TRANSTECH PHARMA, LLC HIGH POINT, NC | 32621/860 | ECORSEXC, file of 2026-09-25 |
| 2013-11-25 | Assignment Assignment of assignor's interest | NOVO NORDISK A/S signed 2009-07-29 | TRANSTECH PHARMA, INC. HIGH POINT, NC | 31672/21 | ECORSEXC, file of 2026-09-25 |
| 2013-11-25 | Assignment Assignment of assignor's interest | SUBRAMANIAN, GOVINDAN signed 2006-09-05 CHRISTEN, DANIEL PETER signed 2006-09-12 POLISETTI, DHARMA RAO signed 2006-09-12 MJALLI, ADNAN M.M. signed 2006-09-14 ANDREWS, ROBERT CARL signed 2006-09-15 LAU, JESPER F. signed 2006-09-20 MURRAY, ANTHONY signed 2006-09-20 JEPPESEN, LONE signed 2006-09-22 VEDSO, PER signed 2006-09-22 KODRA, JANOS TIBOR signed 2006-09-25 ANKERSEN, MICHAEL signed 2006-09-26 | NOVO NORDISK A/S BAGSVAERD | 31671/983 | ECORSEXC, file of 2026-09-25 |
| 2013-11-22 | Assignment Assignment of assignor's interest | TRANSTECH PHARMA, INC. signed 2013-11-14 | TRANSTECH PHARMA, LLC HIGH POINT, NC | 31654/878 | ECORSEXC, file of 2026-09-25 |
| 2013-08-09 | Security interest Security interest Security agreement | TRANSTECH PHARMA, INC. signed 2013-08-09 | M&F TTP HOLDINGS LLC C/O MACANDREWS & FORBES HOLDINGS INC. NEW YORK, NY | 30982/803 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.