Patents
US 12767721 B2: CD40 antagonist antibody variants with improved pharmacokinetic properties
- Granted
- 2026-10-20
- Filed
- 2021-05-17 application 17999271
- Type
- Utility · 13 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The disclosure provides variants of an antibody wherein the variant antibodies have modified net charge properties relative to the corresponding unmodified antibody. Certain variants have improved pharmacokinetic properties relative to the corresponding unmodified antibody. Certain antibody variants bind CD40. Compositions and methods of use of the same are also provided.
Source: PTBLXML, file of 2026-10-20 (ipgb20261020.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Bristol-Myers Squibb Company 1,812 patents | US company or organization | Princeton, NJ | BRISTOL MYERS SQUIBB CO SEC filer FUZZY low confidence: same name (legal endings aside), one of each nationally | PTBLXML, file of 2026-10-20 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Aaron Yamniuk | Vancouver, CA | PTBLXML, file of 2026-10-20 | ||
| Mary Struthers | Princeton, NJ | 13 | PTBLXML, file of 2026-10-20 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K16/2878 | PTBLXML, file of 2026-10-20 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K39/3955 | PTBLXML, file of 2026-10-20 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P37/06 | PTBLXML, file of 2026-10-20 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.