Patents

US 12760336 B2: Methods and compositions for the production of acetyl-CoA derived products

Granted
2026-10-13
Filed
2021-07-23 application 18006506
Type
Utility · 17 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure is related to genetically engineered microbial strains and related bioprocesses for the production of products from acetyl-CoA. Specifically, the use of dynamically controlled synthetic metabolic valves to reduce the activity of certain enzymes, leads to increased product production in a two-stage process.

Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Duke University 1,375 patentsUS company or organizationDurham, NCDuke University College or university EXACT high confidence: identical full name and state
DUKE UNIVERSITY Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-10-13

Inventors

InventorPlacePatentsPerson pageSource
Michael David LynchDurham, NCPTBLXML, file of 2026-10-13
Shuai LiDurham, NCPTBLXML, file of 2026-10-13

CPC categories

SubclassCategoryFirst groupSource
C12PFermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixtureC12P7/44PTBLXML, file of 2026-10-13
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N9/0006PTBLXML, file of 2026-10-13
C12YEnzymesC12Y101/01049PTBLXML, file of 2026-10-13

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.