Patents
US 12760268 B2: Compositions and methods related to transferrin receptor-binding aptamers
- Granted
- 2026-10-13
- Filed
- 2022-07-15 application 17813021
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Described herein are aptamers that bind to the transferrin receptor (e.g., CD71) and can be used, in part, for depleting transferrin receptor-expressing cells from a population of therapeutic cells. These aptamer compositions can be used in methods for isolating and/or enriching cells expressing CD71 or depleting cell populations of cells expressing CD71, including for example, tumor cells. Further provided are methods of using the aptamers or cell populations generated using them in the methods disclosed herein for therapies and/or drug delivery.
Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Washington 1,041 patents | US company or organization | Seattle, WA | UNIVERSITY OF WASHINGTON State business registration EXACT high confidence: identical full name and state UNIVERSITY OF WASHINGTON Federal lobbying client EXACT high confidence: identical full name and state UNIVERSITY OF WASHINGTON Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-13 |
| Seattle Children's Hospital 103 patents | US company or organization | Seattle, WA | SEATTLE CHILDREN'S HOSPITAL State business registration EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Suzie Hwang Pun | Seattle, WA | 12 | PTBLXML, file of 2026-10-13 | |
| Nataly Kacherovsky | Seattle, WA | 4 | PTBLXML, file of 2026-10-13 | |
| Emmeline Cheng | Seattle, WA | 2 | PTBLXML, file of 2026-10-13 | |
| Ian Cardle | Seattle, WA | 3 | PTBLXML, file of 2026-10-13 | |
| Michael Jensen | Seattle, WA | PTBLXML, file of 2026-10-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0093 | PTBLXML, file of 2026-10-13 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K40/11 | PTBLXML, file of 2026-10-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.