Patents
US 12760097 B2: Chimeric antigen receptor modified T-cells (CAR-T) for the treatment of hematological and solid tumor cancers
- Granted
- 2026-10-13
- Filed
- 2020-03-26 application 17598200
- Type
- Utility · 21 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein is a chimeric antigen receptor (CAR) and CAR-expressing immune cells that target human RORI expressed aberrantly on a tumor cancers. Described herein are chimeric antigen receptors that target human ROR-1, cell compositions expressing the chimeric antigen receptors, and methods and uses of the chimeric antigen receptors and/or the cell compositions. The chimeric antigen receptors described herein can be expressed by the T lymphocytes isolated from an individual afflicted with cancer and re-administered to the individual.
Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Regents of the University of California 8,781 patents | US company or organization | Oakland, CA | REGENTS OF THE UNIVERSITY OF CALIFORNIA State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-10-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Charles E. Prussak | Oakland, CA | 8 | PTBLXML, file of 2026-10-13 | |
| Thomas J. Kipps | Oakland, CA | 32 | PTBLXML, file of 2026-10-13 | |
| George F. Widhopf, II | Oakland, CA | 13 | PTBLXML, file of 2026-10-13 | |
| Christopher S. Oh | Oakland, CA | PTBLXML, file of 2026-10-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K16/2803 | PTBLXML, file of 2026-10-13 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K40/11 | PTBLXML, file of 2026-10-13 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/02 | PTBLXML, file of 2026-10-13 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0636 | PTBLXML, file of 2026-10-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.