Patents
US 12759995 B2: Inhibitors of RNA-binding proteins, compositions thereof, and therapeutic uses therof
- Granted
- 2026-10-13
- Filed
- 2020-05-01 application 17607003
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present technology is directed to compounds that inhibit of the interaction of RNA-binding proteins with RNA, intermediates thereof, compositions thereof, and methods of treatment utilizing such compounds, where the compounds are of Formula I, where Z1 is aryl, heteroaryl, cycloalkyl; L′ is absent, —CH2—, —CH2—CH2—, or —CH≡CH—; X1 is O, NH, or S; and X2 is OH, NH2, NH—OH, NH—NH2, or O—(C1-C6 alkyl).
Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The University of North Carolina 15 patents | US company or organization | Chapel Hill, NC | UNIVERSITY OF NORTH CAROLINA Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-13 |
| University of Kansas 437 patents | US company or organization | Lawrence, KS | University of Kansas College or university EXACT high confidence: identical full name and state UNIVERSITY OF KANSAS Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jeff Aube | Chapel Hill, NC | PTBLXML, file of 2026-10-13 | ||
| Sudeshna Roy | Lawrence, KS | 2 | PTBLXML, file of 2026-10-13 | |
| Liang Xu | Lawrence, KS | 8 | PTBLXML, file of 2026-10-13 | |
| Xiaoqing Wu | Lawrence, KS | PTBLXML, file of 2026-10-13 | ||
| Lan Lan | Lawrence, KS | PTBLXML, file of 2026-10-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D333/60 | PTBLXML, file of 2026-10-13 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-10-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.