Patents
US 12758973 B2: Micro-fluidic system using micro-apertures for high throughput detection of cells
- Granted
- 2026-10-13
- Filed
- 2021-07-30 application 17390404
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber.
Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Purdue Research Foundation 2,151 patents | US company or organization | West Lafayette, IN | PURDUE RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Cagri A. Savran | West Lafayette, IN | 18 | PTBLXML, file of 2026-10-13 | |
| Philip S. Low | West Lafayette, IN | PTBLXML, file of 2026-10-13 | ||
| Chun-Li Chang | West Lafayette, IN | 13 | PTBLXML, file of 2026-10-13 | |
| Wanfeng Huang | San Jose, CA | 8 | PTBLXML, file of 2026-10-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| B01L | Chemical or physical laboratory apparatus for general use | B01L3/502761 | PTBLXML, file of 2026-10-13 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N27/745 | PTBLXML, file of 2026-10-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.