Patents

US 12758895 B2: Methods for the purification of L-glufosinate

Granted
2026-10-13
Filed
2024-04-05 application 18628116
Type
Utility · 2 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Compositions and methods for isolating L-glufosinate from a composition comprising L-glufosinate and glutamate are provided. The method comprises converting the glutamate to pyroglutamate followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The composition comprising L-glufosinate and glutamate is subjected to an elevated temperature for a sufficient time to allow for the conversion of glutamate to pyroglutamate, followed by the isolation of L-glufosinate from the pyroglutamate and other components of the composition to obtain substantially purified L-glufosinate. The glutamate alternatively may be converted to pyroglutamate by enzymatic conversion. The purified L-glufosinate is present in a final composition at a concentration of 90% or greater of the sum of L-glufosinate, glutamate, and pyroglutamate. In some embodiments, a portion of the glutamate in the starting composition may be separated from the L-glufosinate using a crystallization step. Solid forms of L-glufosinate materials, including crystalline L-glufosinate ammonium, are also described.

Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
BASF SE 6,481 patentsForeign company or organizationLudwigshafen, DEPTBLXML, file of 2026-10-13

Inventors

InventorPlacePatentsPerson pageSource
Stephen Craig FieldsBaltimore, MD5PTBLXML, file of 2026-10-13
Matthew Richard OberholzerWilmington, DE14PTBLXML, file of 2026-10-13
Brian Michael GreenLutherville, MD20PTBLXML, file of 2026-10-13
Samir KulkarniEast Lyme, CT7PTBLXML, file of 2026-10-13
Jennifer NelsonKokomo, IN20PTBLXML, file of 2026-10-13
Patricia AndresWest Lafayette, IN50PTBLXML, file of 2026-10-13

CPC categories

SubclassCategoryFirst groupSource
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or telluriumC07F9/535PTBLXML, file of 2026-10-13

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

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