Patents

US 12758582 B2: Anti-CD33 antibodies and uses thereof

Granted
2026-10-13
Filed
2021-03-31 application 17995089
Type
Utility · 18 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

A suite of novel anti-CD33 antibodies is described. The provided antibodies are pan-binders, binding the C2-set Ig-like domain in the presence or absence of the V-set Ig-like domain of CD33; are C2-set specific binders, binding the C2-set Ig-like domain only in the absence of the V-set Ig-like domain of CD33; or are V-set binders, binding the V-set Ig-like domain of CD33. The antibodies provide novel therapeutic and diagnostic tools against CD33-related disorders, such as acute myeloid leukemia (AML).

Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Fred Hutchinson Cancer Center 81 patentsUS company or organizationSeattle, WAFRED HUTCHINSON CANCER CENTER Nonprofit EXACT high confidence: identical full name and statePTBLXML, file of 2026-10-13

Inventors

InventorPlacePatentsPerson pageSource
Roland B. WalterSeattle, WAPTBLXML, file of 2026-10-13
George S. LaszloSeattle, WA4PTBLXML, file of 2026-10-13

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K35/17PTBLXML, file of 2026-10-13
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P35/02PTBLXML, file of 2026-10-13
C07KPeptidesC07K16/2803PTBLXML, file of 2026-10-13

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.