Patents
US 12758557 B2: Small molecule regulators of alveolar type 2 cell proliferation for the treatment of pulmonary diseases
- Granted
- 2026-10-13
- Filed
- 2022-01-14 application 18261467
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure relates to compounds. and to their pharmaceutical compositions. that inhibit dipeptidyl peptidase IV (DPP4). Hie compounds selectively promote the proliferation of alveolar type 2 cells (AEC2s) and are useful in therapeutic methods of treating diseases whose etiology, for example, derives from epithelial degeneration and maladaptive remodeling, such as pulmonary' diseases like idiopathic pulmonary fibrosis (IFF), acute respiratory' distress syndrome (ARDS), and infant respiratory' distress syndromes (IRDS).
Source: PTBLXML, file of 2026-10-13 (ipgb20261013.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE SCRIPPS RESEARCH INSTITUTE 569 patents | US company or organization | La Jolla, CA | The Scripps Research Institute State business registration EXACT high confidence: identical full name and state SCRIPPS RESEARCH INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-10-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Michael J. Bollong | San Diego, CA | 6 | PTBLXML, file of 2026-10-13 | |
| Peter G. Schultz | La Jolla, CA | 112 | Person page FUZZY high confidence | PTBLXML, file of 2026-10-13 |
| Sida Shao | San Diego, CA | PTBLXML, file of 2026-10-13 | ||
| Arnab Chatterjee | San Diego, CA | PTBLXML, file of 2026-10-13 | ||
| Jian Jeffrey Chen | San Diego, CA | 36 | PTBLXML, file of 2026-10-13 | |
| Zhang | San Diego, CA | PTBLXML, file of 2026-10-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/522 | PTBLXML, file of 2026-10-13 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P11/00 | PTBLXML, file of 2026-10-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.