Patents
US 12751929 B2: Engineered cells and uses thereof
- Granted
- 2026-10-06
- Filed
- 2020-09-11 application 17642320
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure relates to antigen presenting cells and uses thereof for treating sepsis. In some aspects, disclosed herein is an antigen presenting cell, comprising: a lipid-based nanoparticle, comprising: a recombinant polynucleotide, comprising: a first nucleic acid encoding an antimicrobial peptide; a second nucleic acid encoding cathepsin B; and a third nucleic acid encoding a linker; and a vitamin-lipid.
Source: PTBLXML, file of 2026-10-06 (ipgb20261006.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| OHIO STATE INNOVATION FOUNDATION 733 patents | US company or organization | Columbus, OH | OHIO STATE INNOVATION FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-10-06 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Yizhou Dong | Dublin, OH | 26 | PTBLXML, file of 2026-10-06 | |
| Xucheng Hou | Columbus, OH | PTBLXML, file of 2026-10-06 | ||
| Xinfu Zhang | Dalian, CN | 8 | PTBLXML, file of 2026-10-06 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/5123 | PTBLXML, file of 2026-10-06 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/04 | PTBLXML, file of 2026-10-06 |
| C07K | Peptides | C07K7/08 | PTBLXML, file of 2026-10-06 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0645 | PTBLXML, file of 2026-10-06 |
| C12Y | Enzymes | C12Y304/22001 | PTBLXML, file of 2026-10-06 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.